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7-Deazaxanthine, a novel prototype inhibitor of thymidine phosphorylase.
Balzarini J, Gamboa AE, Esnouf R, Liekens S, Neyts J, De Clercq E, Camarasa MJ, Pérez-Pérez MJ. Balzarini J, et al. Among authors: liekens s. FEBS Lett. 1998 Oct 30;438(1-2):91-5. doi: 10.1016/s0014-5793(98)01271-x. FEBS Lett. 1998. PMID: 9821965 Free article.
The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2'-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes.
Vande Voorde J, Liekens S, McGuigan C, Murziani PG, Slusarczyk M, Balzarini J. Vande Voorde J, et al. Among authors: liekens s. Biochem Pharmacol. 2011 Sep 1;82(5):441-52. doi: 10.1016/j.bcp.2011.05.024. Epub 2011 May 31. Biochem Pharmacol. 2011. PMID: 21658373 Free article.
142 results