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The nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse model of childhood acute lymphoblastic leukemia reveals intrinsic differences in biologic characteristics at diagnosis and relapse.
Lock RB, Liem N, Farnsworth ML, Milross CG, Xue C, Tajbakhsh M, Haber M, Norris MD, Marshall GM, Rice AM. Lock RB, et al. Among authors: Liem N. Blood. 2002 Jun 1;99(11):4100-8. doi: 10.1182/blood.v99.11.4100. Blood. 2002. PMID: 12010813
Variegated clonality and rapid emergence of new molecular lesions in xenografts of acute lymphoblastic leukemia are associated with drug resistance.
Nowak D, Liem NL, Mossner M, Klaumünzer M, Papa RA, Nowak V, Jann JC, Akagi T, Kawamata N, Okamoto R, Thoennissen NH, Kato M, Sanada M, Hofmann WK, Ogawa S, Marshall GM, Lock RB, Koeffler HP. Nowak D, et al. Among authors: Liem NL. Exp Hematol. 2015 Jan;43(1):32-43.e1-35. doi: 10.1016/j.exphem.2014.09.007. Epub 2014 Oct 29. Exp Hematol. 2015. PMID: 25450514 Free PMC article.
Pharmacokinetic modeling of an induction regimen for in vivo combined testing of novel drugs against pediatric acute lymphoblastic leukemia xenografts.
Szymanska B, Wilczynska-Kalak U, Kang MH, Liem NL, Carol H, Boehm I, Groepper D, Reynolds CP, Stewart CF, Lock RB. Szymanska B, et al. Among authors: Liem NL. PLoS One. 2012;7(3):e33894. doi: 10.1371/journal.pone.0033894. Epub 2012 Mar 29. PLoS One. 2012. PMID: 22479469 Free PMC article.
Methylation subtypes and large-scale epigenetic alterations in gastric cancer.
Zouridis H, Deng N, Ivanova T, Zhu Y, Wong B, Huang D, Wu YH, Wu Y, Tan IB, Liem N, Gopalakrishnan V, Luo Q, Wu J, Lee M, Yong WP, Goh LK, Teh BT, Rozen S, Tan P. Zouridis H, et al. Among authors: Liem N. Sci Transl Med. 2012 Oct 17;4(156):156ra140. doi: 10.1126/scitranslmed.3004504. Sci Transl Med. 2012. PMID: 23076357