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The lack of estrogen and excess luteinizing hormone are responsible for the female ArKO mouse phenotype.
Liew SH, Drummond AE, Jones ME, Findlay JK. Liew SH, et al. Mol Cell Endocrinol. 2010 Oct 7;327(1-2):56-64. doi: 10.1016/j.mce.2010.05.003. Epub 2010 May 28. Mol Cell Endocrinol. 2010. PMID: 20546829
Estrogen signaling in the regulation of female reproductive functions.
Findlay JK, Liew SH, Simpson ER, Korach KS. Findlay JK, et al. Among authors: liew sh. Handb Exp Pharmacol. 2010;(198):29-35. doi: 10.1007/978-3-642-02062-9_2. Handb Exp Pharmacol. 2010. PMID: 20839084 Free PMC article. Review.
Estrogen-dependent gene expression in the mouse ovary.
Liew SH, Sarraj MA, Drummond AE, Findlay JK. Liew SH, et al. PLoS One. 2011 Feb 9;6(2):e14672. doi: 10.1371/journal.pone.0014672. PLoS One. 2011. PMID: 21347412 Free PMC article.
DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa.
Kerr JB, Hutt KJ, Michalak EM, Cook M, Vandenberg CJ, Liew SH, Bouillet P, Mills A, Scott CL, Findlay JK, Strasser A. Kerr JB, et al. Among authors: liew sh. Mol Cell. 2012 Nov 9;48(3):343-52. doi: 10.1016/j.molcel.2012.08.017. Epub 2012 Sep 20. Mol Cell. 2012. PMID: 23000175 Free PMC article.
Loss of the proapoptotic BH3-only protein BCL-2 modifying factor prolongs the fertile life span in female mice.
Liew SH, Vaithiyanathan K, Cook M, Bouillet P, Scott CL, Kerr JB, Strasser A, Findlay JK, Hutt KJ. Liew SH, et al. Biol Reprod. 2014 Apr 10;90(4):77. doi: 10.1095/biolreprod.113.116947. Print 2014 Apr. Biol Reprod. 2014. PMID: 24571986
PUMA regulates germ cell loss and primordial follicle endowment in mice.
Myers M, Morgan FH, Liew SH, Zerafa N, Gamage TU, Sarraj M, Cook M, Kapic I, Sutherland A, Scott CL, Strasser A, Findlay JK, Kerr JB, Hutt KJ. Myers M, et al. Among authors: liew sh. Reproduction. 2014 Aug;148(2):211-9. doi: 10.1530/REP-13-0666. Epub 2014 May 23. Reproduction. 2014. PMID: 24859845
Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary.
Best SA, Hutt KJ, Fu NY, Vaillant F, Liew SH, Hartley L, Scott CL, Lindeman GJ, Visvader JE. Best SA, et al. Among authors: liew sh. Development. 2014 Aug;141(16):3159-64. doi: 10.1242/dev.108498. Epub 2014 Jul 18. Development. 2014. PMID: 25038044
Taking control of the female fertile lifespan: a key role for Bcl-2 family proteins.
Liew SH, Vaithiyanathan K, Hutt KJ. Liew SH, et al. Reprod Fertil Dev. 2016 Jun;28(7):864-871. doi: 10.1071/RD14326. Reprod Fertil Dev. 2016. PMID: 25423414 Review.
Nicotinamide mononucleotide does not protect the ovarian reserve from cancer treatments.
Stringer J, Groenewegen E, Liew SH, Hutt KJ. Stringer J, et al. Among authors: liew sh. Reproduction. 2019 Nov 1:REP-19-0337.R2. doi: 10.1530/REP-19-0337. Online ahead of print. Reproduction. 2019. PMID: 31751296
BCL2-modifying factor promotes germ cell loss during murine oogenesis.
Vaithiyanathan K, Liew SH, Zerafa N, Gamage T, Cook M, O'Reilly LA, Bouillet P, Scott CL, Strasser A, Findlay JK, Hutt KJ. Vaithiyanathan K, et al. Among authors: liew sh. Reproduction. 2016 May;151(5):553-62. doi: 10.1530/REP-15-0561. Epub 2016 Feb 25. Reproduction. 2016. PMID: 26917450
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