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Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice.
Yang W, Li T, An S, Chen R, Zhao Y, Cui J, Zhang M, Lu J, Tian Y, Bao L, Zhao P. Yang W, et al. Microbiol Spectr. 2025 Feb 4;13(2):e0186124. doi: 10.1128/spectrum.01861-24. Epub 2025 Jan 10. Microbiol Spectr. 2025. PMID: 39792005 Free PMC article.
The levels of autophagy and apoptosis proteins, tight junction proteins, and inflammatory factors were detected by western blotting, immunofluorescence assay, and enzyme-linked immunosorbent assay. High-throughput sequencing of gut 16S rRNA was performed to analyze the abu …
The levels of autophagy and apoptosis proteins, tight junction proteins, and inflammatory factors were detected by western blotting, immunof …
The Role of Probiotics Limosilactobacillus reuteri, Ligilactobacillus salivarius, and Lactobacillus johnsonii in Inhibziting Pathogens, Maintaining Gut Health, and Improving Disease Outcomes.
Li L, Qiu X, Lu S, Yu H, Lu P, Zeng S, Deng A, Zhu M, Xu E, Niu J. Li L, et al. Int J Mol Sci. 2026 Feb 4;27(3):1545. doi: 10.3390/ijms27031545. Int J Mol Sci. 2026. PMID: 41683964 Free PMC article. Review.
As the critical component of the gastrointestinal tract, which lives in trillions of gut microorganisms, in a healthy state, the host interacts with the gut microbiota and is symbiotic. The species Limosilactobacillus reuteri, Ligilactobacillus sali …
As the critical component of the gastrointestinal tract, which lives in trillions of gut microorganisms, in a healthy state, t …
Effects of phototherapy combined with Lactobacillus salivarius AP-32 or Bifidobacterium animalis subsp. lactis CP-9 on improving neonatal jaundice and gut microbiome health: a randomized double-blind clinical study.
Tsai ML, Shen SP, Chen YT, Chiu HY, Lin HY, Cheng HW, Kuo YW, Lin JH, Wang HS, Huang YY, Li CM, Chin YH, Ho HH, Lin HC. Tsai ML, et al. Nutr J. 2025 May 9;24(1):73. doi: 10.1186/s12937-025-01126-4. Nutr J. 2025. PMID: 40346590 Free PMC article. Clinical Trial.
The AP-32 group showed a significant increase in the abundance of L. salivarius, while the CP-9 group demonstrated a notable enhancement in the abundance of B. animalis. These findings suggest that integrating phototherapy with probiotic supplementation may enhance jaundic …
The AP-32 group showed a significant increase in the abundance of L. salivarius, while the CP-9 group demonstrated a notable enhancem …
Assessment of the safety and gut microbiota modulation ability of an infant formula containing Bifidobacterium animalis ssp. lactis CP-9 or Lactobacillus salivarius AP-32 and the effects of the formula on infant growth outcomes: insights from a four-month clinical study in infants under two months old.
Shen SP, Lin HC, Chen JF, Wang HS, Huang YY, Hsia KC, Lin JH, Kuo YW, Li CM, Hsu YC, Tsai SY, Ho HH. Shen SP, et al. BMC Pediatr. 2024 Dec 27;24(1):840. doi: 10.1186/s12887-024-05289-7. BMC Pediatr. 2024. PMID: 39731060 Free PMC article. Clinical Trial.
The safety of these strains in terms of antibiotic resistance and their ability to modulate the gut microbiota were also evaluated. METHODS: One hundred eighty healthy infants were included in this study and separated into three groups: the control group, the L. salivar …
The safety of these strains in terms of antibiotic resistance and their ability to modulate the gut microbiota were also evaluated. M …
Lactobacillus salivarius extracellular vesicles enhance gut and liver function in MAFLD.
Zhu L, Huang J, Luo Z, Yan H, Wu X, Liao R. Zhu L, et al. Front Immunol. 2025 Aug 28;16:1660131. doi: 10.3389/fimmu.2025.1660131. eCollection 2025. Front Immunol. 2025. PMID: 40948779 Free PMC article.
BACKGROUND: Metabolic dysfunction-associated fatty liver disease (MAFLD) is associated with an accumulation of fat in the liver, disruptions in lipid metabolism, and imbalances in the gut microbiome. Extracellular vesicles (EVs) derived from probiotics have emerged …
BACKGROUND: Metabolic dysfunction-associated fatty liver disease (MAFLD) is associated with an accumulation of fat in the liver, disruptions …
Assessment of beneficial effects and identification of host adaptation-associated genes of Ligilactobacillus salivarius isolated from badgers.
Wang Y, Xu X, Chen H, Yang F, Xu B, Wang K, Liu Q, Liang G, Zhang R, Jiao X, Zhang Y. Wang Y, et al. BMC Genomics. 2023 Sep 7;24(1):530. doi: 10.1186/s12864-023-09623-8. BMC Genomics. 2023. PMID: 37679681 Free PMC article.
BACKGROUND: Ligilactobacillus salivarius has been frequently isolated from the gut microbiota of humans and domesticated animals and has been studied as a candidate probiotic. ...CONCLUSIONS: A candidate probiotic and nine L. salivarius complete genome …
BACKGROUND: Ligilactobacillus salivarius has been frequently isolated from the gut microbiota of humans and domesticate …
Investigating the Metabolism of Estrogens in Ligilactobacillus salivarius Strains Isolated from Human Milk and Vaginal Microbiota.
Aragón A, Jurado R, Jara J, Rodríguez JM, Orgaz B. Aragón A, et al. Nutrients. 2024 Mar 16;16(6):861. doi: 10.3390/nu16060861. Nutrients. 2024. PMID: 38542771 Free PMC article.
The interplay between enterohepatic circulation and the gut microbiota is the main driver determining systemic levels of estrogens and their metabolites. ...In this work, we have explored the ability of six Ligilactobacillus salivarius strains isolated from h …
The interplay between enterohepatic circulation and the gut microbiota is the main driver determining systemic levels of estrogens an …
A Two Bacteriocinogenic Ligilactobacillus Strain Association Inhibits Growth, Adhesion, and Invasion of Salmonella in a Simulated Chicken Gut Environment.
Miri S, Hassan H, Esmail GA, Njoku EN, Chiba M, Yousuf B, Ahmed TAE, Hincke M, Mottawea W, Hammami R. Miri S, et al. Probiotics Antimicrob Proteins. 2024 Dec;16(6):2021-2038. doi: 10.1007/s12602-023-10148-5. Epub 2023 Aug 30. Probiotics Antimicrob Proteins. 2024. PMID: 37646968
A biocompatibility coculture test was performed, which identified two biocompatible strains, Ligilactobacillus salivarius UO.C109 and Ligilactobacillus saerimneri UO.C121 with high inhibitory activity against Salmonella. ...It also modulated microbiome …
A biocompatibility coculture test was performed, which identified two biocompatible strains, Ligilactobacillus salivarius UO.C …
Probiotics suppress LL37 generated rosacea-like skin inflammation by modulating the TLR2/MyD88/NF-κB signaling pathway.
Qi X, Xiao Y, Zhang X, Zhu Z, Zhang H, Wei J, Zhao Z, Li J, Chen T. Qi X, et al. Food Funct. 2024 Aug 27;15(17):8916-8934. doi: 10.1039/d4fo03083d. Food Funct. 2024. PMID: 39143863
In this study, we screened and isolated strains Ligilactobacillus salivarius 23-006 and Lacticaseibacillus paracasei 23-008 from the feces of healthy volunteers and evaluated the intervention effects of probiotics on rosacea by constructing an LL37 induced rosacea-l …
In this study, we screened and isolated strains Ligilactobacillus salivarius 23-006 and Lacticaseibacillus paracasei 23-008 fr …
UCC118 supplementation reduces exercise-induced gastrointestinal permeability and remodels the gut microbiome in healthy humans.
Axelrod CL, Brennan CJ, Cresci G, Paul D, Hull M, Fealy CE, Kirwan JP. Axelrod CL, et al. Physiol Rep. 2019 Nov;7(22):e14276. doi: 10.14814/phy2.14276. Physiol Rep. 2019. PMID: 31758610 Free PMC article. Clinical Trial.
Dysregulation of gut microbiota and intestinal barrier function has emerged as potential mechanisms underlying digestive diseases, yet targeted therapies are lacking The purpose of this investigation was to assess the efficacy of UCC118, a characterized probiotic strain, o …
Dysregulation of gut microbiota and intestinal barrier function has emerged as potential mechanisms underlying digestive diseases, ye …
25 results