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2016 4
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38 results

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Page 1
Polypharmacology of S-1117, an Fc-fused IgG-selective degrading enzyme, for chronic treatment of autoantibody-mediated diseases.
Sanmarco LM, Pellerin A, Green T, Plasencia A, Anderson JM, Le N, Newton A, Chen J, Ramello MC, Peckner R, Manasson J, Xing Y, Vital H, Higginson-Scott N, Sundy JS, Otipoby KL, Mascanfroni ID. Sanmarco LM, et al. Proc Natl Acad Sci U S A. 2026 Mar 31;123(13):e2518366123. doi: 10.1073/pnas.2518366123. Epub 2026 Mar 25. Proc Natl Acad Sci U S A. 2026. PMID: 41880580 Free PMC article.
Therapeutic IgG- and IgM-specific proteases disarm the acetylcholine receptor autoantibodies that drive myasthenia gravis pathology.
Bayer AC, Sanmarco LM, Pellerin A, Masi G, Plasencia A, Anderson JM, Nowak RJ, Damato V, Massacesi L, Pham MC, Khani-Habibabadi F, Vital H, Higginson-Scott N, Otipoby KL, Xing Y, Mascanfroni ID, O'Connor KC. Bayer AC, et al. Among authors: sanmarco lm. Proc Natl Acad Sci U S A. 2025 Oct 28;122(43):e2505984122. doi: 10.1073/pnas.2505984122. Epub 2025 Oct 21. Proc Natl Acad Sci U S A. 2025. PMID: 41118207 Free PMC article.
Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: sanmarco lm. Nature. 2025 Sep;645(8081):E5. doi: 10.1038/s41586-025-09546-2. Nature. 2025. PMID: 40858938 No abstract available.
Barcoded viral tracing identifies immunosuppressive astrocyte-glioma interactions.
Andersen BM, Faust Akl C, Wheeler MA, Li Z, Diebold M, Kilian M, Rone JM, Misra A, Kenison JE, Lee JH, Lee HG, Polonio CM, Merrell D, Weiss JH, Godinez L, Piester G, Illouz T, Ye JJ, Ghia A, Martinez J, Chung EN, Srun L, Farrenkopf D, Flausino LE, Schüle AM, Sanmarco LM, Giovannoni F, Fehrenbacher L, Charabati M, Gutiérrez-Vázquez C, Cusick MM, Prabhakar PS, Bossi CC, Lapinskas E, Nowarski R, Getz G, Ligon KL, Prinz M, Chiocca EA, Reardon DA, Quintana FJ. Andersen BM, et al. Among authors: sanmarco lm. Nature. 2025 Aug;644(8078):1097-1106. doi: 10.1038/s41586-025-09191-9. Epub 2025 Jun 25. Nature. 2025. PMID: 40562937 Free PMC article.
Glioblastoma-instructed astrocytes suppress tumour-specific T cell immunity.
Faust Akl C, Andersen BM, Li Z, Giovannoni F, Diebold M, Sanmarco LM, Kilian M, Fehrenbacher L, Pernin F, Rone JM, Lee HG, Piester G, Kenison JE, Lee JH, Illouz T, Polonio CM, Srun L, Martinez J, Chung EN, Schüle A, Plasencia A, Li L, Ferrara K, Lewandrowski M, Strathdee CA, Lerner L, Quéva C, Clark IC, Deneen B, Lieberman J, Sherr DH, Antel JP, Wheeler MA, Ligon KL, Chiocca EA, Prinz M, Reardon DA, Quintana FJ. Faust Akl C, et al. Among authors: sanmarco lm. Nature. 2025 Jul;643(8070):219-229. doi: 10.1038/s41586-025-08997-x. Epub 2025 May 21. Nature. 2025. PMID: 40399681 Free PMC article.
Author Correction: Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: sanmarco lm. Nature. 2024 Jul;631(8020):E8. doi: 10.1038/s41586-024-07734-0. Nature. 2024. PMID: 38907058 No abstract available.
Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: sanmarco lm. Nature. 2024 Mar;627(8005):865-872. doi: 10.1038/s41586-024-07187-5. Epub 2024 Mar 20. Nature. 2024. PMID: 38509377 Free PMC article.
Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel J, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: sanmarco lm. bioRxiv [Preprint]. 2024 Jan 5:2024.01.04.574196. doi: 10.1101/2024.01.04.574196. bioRxiv. 2024. Update in: Nature. 2024 Mar;627(8005):865-872. doi: 10.1038/s41586-024-07187-5. PMID: 38260616 Free PMC article. Updated. Preprint.
Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Stevens NA, Piester G, Chung EN, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Sanmarco LM, et al. Nature. 2023 Aug;620(7975):881-889. doi: 10.1038/s41586-023-06409-6. Epub 2023 Aug 9. Nature. 2023. PMID: 37558878 Free PMC article.
Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
Sanmarco LM, Rone JM, Polonio CM, Giovannoni F, Lahore GF, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Akl CF, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Piester G, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Sanmarco LM, et al. bioRxiv [Preprint]. 2023 Mar 21:2023.03.17.532101. doi: 10.1101/2023.03.17.532101. bioRxiv. 2023. Update in: Nature. 2023 Aug;620(7975):881-889. doi: 10.1038/s41586-023-06409-6. PMID: 36993446 Free PMC article. Updated. Preprint.
38 results