Lim CU - Search Results

1

CDK8 Selectively Promotes the Growth of Colon Cancer Metastases in the Liver by Regulating Gene Expression of TIMP3 and Matrix Metalloproteinases.

Liang J, Chen M, Hughes D, Chumanevich AA, Altilia S, Kaza V, Lim CU, Kiaris H, Mythreye K, Pena MM, Broude EV, Roninson IB. Liang J, et al. Among authors: lim cu. Cancer Res. 2018 Dec 1;78(23):6594-6606. doi: 10.1158/0008-5472.CAN-18-1583. Epub 2018 Sep 5. Cancer Res. 2018. PMID: 30185549 Free PMC article.

2

Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1.

Shtutman M, Baig M, Levina E, Hurteau G, Lim CU, Broude E, Nikiforov M, Harkins TT, Carmack CS, Ding Y, Wieland F, Buttyan R, Roninson IB. Shtutman M, et al. Among authors: lim cu. Proc Natl Acad Sci U S A. 2011 Jul 26;108(30):12449-54. doi: 10.1073/pnas.1103842108. Epub 2011 Jul 11. Proc Natl Acad Sci U S A. 2011. PMID: 21746916 Free PMC article.

3

Effects of conditional depletion of topoisomerase II on cell cycle progression in mammalian cells.

Gonzalez RE, Lim CU, Cole K, Bianchini CH, Schools GP, Davis BE, Wada I, Roninson IB, Broude EV. Gonzalez RE, et al. Among authors: lim cu. Cell Cycle. 2011 Oct 15;10(20):3505-14. doi: 10.4161/cc.10.20.17778. Cell Cycle. 2011. PMID: 22067657 Free PMC article.

4

Cyclin-dependent kinase 8 mediates chemotherapy-induced tumor-promoting paracrine activities.

Porter DC, Farmaki E, Altilia S, Schools GP, West DK, Chen M, Chang BD, Puzyrev AT, Lim CU, Rokow-Kittell R, Friedhoff LT, Papavassiliou AG, Kalurupalle S, Hurteau G, Shi J, Baran PS, Gyorffy B, Wentland MP, Broude EV, Kiaris H, Roninson IB. Porter DC, et al. Among authors: lim cu. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13799-804. doi: 10.1073/pnas.1206906109. Epub 2012 Aug 6. Proc Natl Acad Sci U S A. 2012. PMID: 22869755 Free PMC article.

5

Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.

Levina E, Ji H, Chen M, Baig M, Oliver D, Ohouo P, Lim CU, Schools G, Carmack S, Ding Y, Broude EV, Roninson IB, Buttyan R, Shtutman M. Levina E, et al. Among authors: lim cu. Oncotarget. 2015 May 30;6(15):13088-104. doi: 10.18632/oncotarget.3743. Oncotarget. 2015. PMID: 26036626 Free PMC article.

6

Inhibition of CDK8 mediator kinase suppresses estrogen dependent transcription and the growth of estrogen receptor positive breast cancer.

McDermott MS, Chumanevich AA, Lim CU, Liang J, Chen M, Altilia S, Oliver D, Rae JM, Shtutman M, Kiaris H, Győrffy B, Roninson IB, Broude EV. McDermott MS, et al. Among authors: lim cu. Oncotarget. 2017 Feb 21;8(8):12558-12575. doi: 10.18632/oncotarget.14894. Oncotarget. 2017. PMID: 28147342 Free PMC article.

7

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.

Chen M, Liang J, Ji H, Yang Z, Altilia S, Hu B, Schronce A, McDermott MSJ, Schools GP, Lim CU, Oliver D, Shtutman MS, Lu T, Stark GR, Porter DC, Broude EV, Roninson IB. Chen M, et al. Among authors: lim cu. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10208-10213. doi: 10.1073/pnas.1710467114. Epub 2017 Aug 30. Proc Natl Acad Sci U S A. 2017. PMID: 28855340 Free PMC article.

8

CDK7 Inhibition is Effective in all the Subtypes of Breast Cancer: Determinants of Response and Synergy with EGFR Inhibition.

McDermott MSJ, Sharko AC, Munie J, Kassler S, Melendez T, Lim CU, Broude EV. McDermott MSJ, et al. Among authors: lim cu. Cells. 2020 Mar 6;9(3):638. doi: 10.3390/cells9030638. Cells. 2020. PMID: 32155786 Free PMC article.

9

The Inhibition of CDK8/19 Mediator Kinases Prevents the Development of Resistance to EGFR-Targeting Drugs.

Sharko AC, Lim CU, McDermott MSJ, Hennes C, Philavong KP, Aiken T, Tatarskiy VV, Roninson IB, Broude EV. Sharko AC, et al. Among authors: lim cu. Cells. 2021 Jan 12;10(1):144. doi: 10.3390/cells10010144. Cells. 2021. PMID: 33445730 Free PMC article.

10

Propensity to endoplasmic reticulum stress in deer mouse fibroblasts predicts skin inflammation and body weight gain.

Zhang Y, Lim CU, Sikirzhytski V, Naderi A, Chatzistamou I, Kiaris H. Zhang Y, et al. Among authors: lim cu. Dis Model Mech. 2021 Oct 1;14(10):dmm049113. doi: 10.1242/dmm.049113. Epub 2021 Oct 18. Dis Model Mech. 2021. PMID: 34661243 Free PMC article.

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