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A novel serine/threonine kinase binding the Ras-related RhoA GTPase which translocates the kinase to peripheral membranes.
Leung T, Manser E, Tan L, Lim L. Leung T, et al. Among authors: lim l. J Biol Chem. 1995 Dec 8;270(49):29051-4. doi: 10.1074/jbc.270.49.29051. J Biol Chem. 1995. PMID: 7493923 Free article.
We previously reported the cloning of a serine/threonine kinase, PAK (for p21 (Cdc42/Rac)-activated kinase), which binds to the Ras-related GTPases Cdc42Hs and Rac1 (Manser, E., Leung, T., Salihuddin, H., Zhao, Z-s., and Lim, L. (1994) Nature 367, 40-46). These p21 …
We previously reported the cloning of a serine/threonine kinase, PAK (for p21 (Cdc42/Rac)-activated kinase), which binds to the Ras-related …
Molecular cloning of a new member of the p21-Cdc42/Rac-activated kinase (PAK) family.
Manser E, Chong C, Zhao ZS, Leung T, Michael G, Hall C, Lim L. Manser E, et al. Among authors: lim l. J Biol Chem. 1995 Oct 20;270(42):25070-8. doi: 10.1074/jbc.270.42.25070. J Biol Chem. 1995. PMID: 7559638 Free article.
A number of "target" proteins for the Rho family of small GTP-binding proteins have now been identified, including the protein kinases ACK and p65PAK (Manser, E., Leung, T., Salihuddin, H., Zhao, Z.-S., and Lim, L. (1994) Nature 367, 40-46). The purified serine/thre …
A number of "target" proteins for the Rho family of small GTP-binding proteins have now been identified, including the protein kinases ACK a …
Identification and molecular cloning of a p21cdc42/rac1-activated serine/threonine kinase that is rapidly activated by thrombin in platelets.
Teo M, Manser E, Lim L. Teo M, et al. Among authors: lim l. J Biol Chem. 1995 Nov 3;270(44):26690-7. doi: 10.1074/jbc.270.44.26690. J Biol Chem. 1995. PMID: 7592896 Free article.
The brain-enriched p21cdc42/rac1-activated serine/threonine kinase, p65PAK, was identified and purified on the basis of overlays with [gamma-32P]GTP-Cdc42 onto SDS-fractionated proteins (Manser, E., Leung, T., Salihuddin, H., Zhao, Z.-S., and Lim, L. (1994) Nature 3 …
The brain-enriched p21cdc42/rac1-activated serine/threonine kinase, p65PAK, was identified and purified on the basis of overlays with [gamma …
The p160 RhoA-binding kinase ROK alpha is a member of a kinase family and is involved in the reorganization of the cytoskeleton.
Leung T, Chen XQ, Manser E, Lim L. Leung T, et al. Among authors: lim l. Mol Cell Biol. 1996 Oct;16(10):5313-27. doi: 10.1128/MCB.16.10.5313. Mol Cell Biol. 1996. PMID: 8816443 Free PMC article.
We recently reported on a p150 serine/threonine kinase (termed ROK alpha) binding RhoA only in its active GTP-bound state and on its cDNA; introduction of RhoA into HeLa cells resulted in translocation of the cytoplasmic kinase to plasma membranes, consistent with ROK alpha being …
We recently reported on a p150 serine/threonine kinase (termed ROK alpha) binding RhoA only in its active GTP-bound state and on its cDNA; i …
3,082 results