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The Ste5 scaffold allosterically modulates signaling output of the yeast mating pathway.
Bhattacharyya RP, Reményi A, Good MC, Bashor CJ, Falick AM, Lim WA. Bhattacharyya RP, et al. Among authors: lim wa. Science. 2006 Feb 10;311(5762):822-6. doi: 10.1126/science.1120941. Epub 2006 Jan 19. Science. 2006. PMID: 16424299
Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors.
Nguyen JT, Turck CW, Cohen FE, Zuckermann RN, Lim WA. Nguyen JT, et al. Among authors: lim wa. Science. 1998 Dec 11;282(5396):2088-92. doi: 10.1126/science.282.5396.2088. Science. 1998. PMID: 9851931
Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex.
Hillier BJ, Christopherson KS, Prehoda KE, Bredt DS, Lim WA. Hillier BJ, et al. Among authors: lim wa. Science. 1999 Apr 30;284(5415):812-5. Science. 1999. PMID: 10221915
Structure of the enabled/VASP homology 1 domain-peptide complex: a key component in the spatial control of actin assembly.
Prehoda KE, Lee DJ, Lim WA. Prehoda KE, et al. Among authors: lim wa. Cell. 1999 May 14;97(4):471-80. doi: 10.1016/s0092-8674(00)80757-6. Cell. 1999. PMID: 10338211
Improving SH3 domain ligand selectivity using a non-natural scaffold.
Nguyen JT, Porter M, Amoui M, Miller WT, Zuckermann RN, Lim WA. Nguyen JT, et al. Among authors: lim wa. Chem Biol. 2000 Jul;7(7):463-73. doi: 10.1016/s1074-5521(00)00130-7. Chem Biol. 2000. PMID: 10903934
Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex.
Prehoda KE, Scott JA, Mullins RD, Lim WA. Prehoda KE, et al. Among authors: lim wa. Science. 2000 Oct 27;290(5492):801-6. doi: 10.1126/science.290.5492.801. Science. 2000. PMID: 11052943
Energetic determinants of internal motif recognition by PDZ domains.
Harris BZ, Hillier BJ, Lim WA. Harris BZ, et al. Among authors: lim wa. Biochemistry. 2001 May 22;40(20):5921-30. doi: 10.1021/bi010142l. Biochemistry. 2001. PMID: 11352727
An analysis of the interactions between the Sem-5 SH3 domain and its ligands using molecular dynamics, free energy calculations, and sequence analysis.
Wang W, Lim WA, Jakalian A, Wang J, Wang J, Luo R, Bayly CI, Kollman PA. Wang W, et al. Among authors: lim wa. J Am Chem Soc. 2001 May 2;123(17):3986-94. doi: 10.1021/ja003164o. J Am Chem Soc. 2001. PMID: 11457149
Mechanism and role of PDZ domains in signaling complex assembly.
Harris BZ, Lim WA. Harris BZ, et al. Among authors: lim wa. J Cell Sci. 2001 Sep;114(Pt 18):3219-31. J Cell Sci. 2001. PMID: 11591811 Review.
Structure of the SH3-guanylate kinase module from PSD-95 suggests a mechanism for regulated assembly of MAGUK scaffolding proteins.
McGee AW, Dakoji SR, Olsen O, Bredt DS, Lim WA, Prehoda KE. McGee AW, et al. Among authors: lim wa. Mol Cell. 2001 Dec;8(6):1291-301. doi: 10.1016/s1097-2765(01)00411-7. Mol Cell. 2001. PMID: 11779504
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