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The molecular mechanisms of oxygen-sensing in human ductus arteriosus smooth muscle cells: A comprehensive transcriptome profile reveals a central role for mitochondria.
Bentley RET, Hindmarch CCT, Dunham-Snary KJ, Snetsinger B, Mewburn JD, Thébaud A, Lima PDA, Thébaud B, Archer SL. Bentley RET, et al. Among authors: lima pda. Genomics. 2021 Sep;113(5):3128-3140. doi: 10.1016/j.ygeno.2021.07.006. Epub 2021 Jul 8. Genomics. 2021. PMID: 34245829 Free PMC article.
Identification of novel dynamin-related protein 1 (Drp1) GTPase inhibitors: Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia-reperfusion injury.
Wu D, Dasgupta A, Chen KH, Neuber-Hess M, Patel J, Hurst TE, Mewburn JD, Lima PDA, Alizadeh E, Martin A, Wells M, Snieckus V, Archer SL. Wu D, et al. Among authors: lima pda. FASEB J. 2020 Jan;34(1):1447-1464. doi: 10.1096/fj.201901467R. Epub 2019 Dec 2. FASEB J. 2020. PMID: 31914641
An epigenetic increase in mitochondrial fission by MiD49 and MiD51 regulates the cell cycle in cancer: Diagnostic and therapeutic implications.
Dasgupta A, Chen KH, Wu D, Hoskin V, Mewburn J, Lima PDA, Parlow LRG, Hindmarch CCT, Martin A, Sykes EA, Tayade C, Lightbody ED, Madarnas Y, SenGupta SK, Elliott BE, Nicol CJB, Archer SL. Dasgupta A, et al. Among authors: lima pda. FASEB J. 2020 Apr;34(4):5106-5127. doi: 10.1096/fj.201903117R. Epub 2020 Feb 18. FASEB J. 2020. PMID: 32068312
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension: A Pyruvate Dehydrogenase Kinase-Dependent Shift in Mitochondrial Metabolism Promotes Right Ventricular Fibrosis.
Tian L, Wu D, Dasgupta A, Chen KH, Mewburn J, Potus F, Lima PDA, Hong Z, Zhao YY, Hindmarch CCT, Kutty S, Provencher S, Bonnet S, Sutendra G, Archer SL. Tian L, et al. Among authors: lima pda. Circ Res. 2020 Jun 5;126(12):1723-1745. doi: 10.1161/CIRCRESAHA.120.316443. Epub 2020 Mar 27. Circ Res. 2020. PMID: 32216531 Free PMC article.
Macrophage-NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension.
Al-Qazazi R, Lima PDA, Prisco SZ, Potus F, Dasgupta A, Chen KH, Tian L, Bentley RET, Mewburn J, Martin AY, Wu D, Jones O, Maurice DH, Bonnet S, Provencher S, Prins KW, Archer SL. Al-Qazazi R, et al. Among authors: lima pda. Am J Respir Crit Care Med. 2022 Sep 1;206(5):608-624. doi: 10.1164/rccm.202110-2274OC. Am J Respir Crit Care Med. 2022. PMID: 35699679 Free PMC article.
SARS-CoV-2 mitochondriopathy in COVID-19 pneumonia exacerbates hypoxemia.
Archer SL, Dasgupta A, Chen KH, Wu D, Baid K, Mamatis JE, Gonzalez V, Read A, Bentley RE, Martin AY, Mewburn JD, Dunham-Snary KJ, Evans GA, Levy G, Jones O, Al-Qazazi R, Ring B, Alizadeh E, Hindmarch CC, Rossi J, Lima PD, Falzarano D, Banerjee A, Colpitts CC. Archer SL, et al. Redox Biol. 2022 Dec;58:102508. doi: 10.1016/j.redox.2022.102508. Epub 2022 Oct 13. Redox Biol. 2022. PMID: 36334378 Free PMC article.
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