Selective escape from CD8+ T-cell responses represents a major driving force of human immunodeficiency virus type 1 (HIV-1) sequence diversity and reveals constraints on HIV-1 evolution.
Allen TM, Altfeld M, Geer SC, Kalife ET, Moore C, O'sullivan KM, Desouza I, Feeney ME, Eldridge RL, Maier EL, Kaufmann DE, Lahaie MP, Reyor L, Tanzi G, Johnston MN, Brander C, Draenert R, Rockstroh JK, Jessen H, Rosenberg ES, Mallal SA, Walker BD.
Allen TM, et al.
J Virol. 2005 Nov;79(21):13239-49. doi: 10.1128/JVI.79.21.13239-13249.2005.
J Virol. 2005.
PMID: 16227247
Free PMC article.
To address this issue we assessed the relationship between genome-wide viral evolution and adaptive CD8+ T-cell responses in four clade B virus-infected patients studied longitudinally for as long as 5 years after acute infection. …
To address this issue we assessed the relationship between genome-wide viral evolution and adaptive CD8+ T-cell respons …