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Lack of elevated MAP kinase (Erk) activity in pancreatic carcinomas despite oncogenic K-ras expression.
Yip-Schneider MT, Lin A, Barnard D, Sweeney CJ, Marshall MS. Yip-Schneider MT, et al. Among authors: lin a. Int J Oncol. 1999 Aug;15(2):271-9. doi: 10.3892/ijo.15.2.271. Int J Oncol. 1999. PMID: 10402237
To explore the biological effects of mutated K-ras, we analyzed the Ras signaling pathway in a panel of cell lines derived from human pancreatic carcinomas. ...
To explore the biological effects of mutated K-ras, we analyzed the Ras signaling pathway in a panel of cell lines derived from human …
Genetic etiology of lung cancer.
Otterson G, Lin A, Kay F. Otterson G, et al. Among authors: lin a. Oncology (Williston Park). 1992 Sep;6(9):97-104, 107; discussion 108, 111-2. Oncology (Williston Park). 1992. PMID: 1449981 Review.
These findings support the hypothesis that lung cancer, as well as other common adult tumors, arise as a result of somatic mutations to a specific group of cellular genes referred to as oncogenes and tumor suppressor genes. New strategies for the prevention and trea …
These findings support the hypothesis that lung cancer, as well as other common adult tumors, arise as a result of somatic mutations …
Gain-of-function mutant p53 activates small GTPase Rac1 through SUMOylation to promote tumor progression.
Yue X, Zhang C, Zhao Y, Liu J, Lin AW, Tan VM, Drake JM, Liu L, Boateng MN, Li J, Feng Z, Hu W. Yue X, et al. Among authors: lin aw. Genes Dev. 2017 Aug 15;31(16):1641-1654. doi: 10.1101/gad.301564.117. Genes Dev. 2017. PMID: 28947497 Free PMC article.
In this study, we found that mutant p53 activates small GTPase Rac1 as a critical mechanism for mutant p53 GOF to promote tumor progression. ...These results uncover a new mechanism for Rac1 activation in tumors and, most importantly, reveal that activation of Rac1 …
In this study, we found that mutant p53 activates small GTPase Rac1 as a critical mechanism for mutant p53 GOF to promote tumor progr …
Origins and genetic legacy of prehistoric dogs.
Bergström A, Frantz L, Schmidt R, Ersmark E, Lebrasseur O, Girdland-Flink L, Lin AT, Storå J, Sjögren KG, Anthony D, Antipina E, Amiri S, Bar-Oz G, Bazaliiskii VI, Bulatović J, Brown D, Carmagnini A, Davy T, Fedorov S, Fiore I, Fulton D, Germonpré M, Haile J, Irving-Pease EK, Jamieson A, Janssens L, Kirillova I, Horwitz LK, Kuzmanovic-Cvetković J, Kuzmin Y, Losey RJ, Dizdar DL, Mashkour M, Novak M, Onar V, Orton D, Pasarić M, Radivojević M, Rajković D, Roberts B, Ryan H, Sablin M, Shidlovskiy F, Stojanović I, Tagliacozzo A, Trantalidou K, Ullén I, Villaluenga A, Wapnish P, Dobney K, Götherström A, Linderholm A, Dalén L, Pinhasi R, Larson G, Skoglund P. Bergström A, et al. Among authors: lin at. Science. 2020 Oct 30;370(6516):557-564. doi: 10.1126/science.aba9572. Epub 2020 Oct 29. Science. 2020. PMID: 33122379
Strategies for Catheter Ablation of Left Ventricular Papillary Muscle Arrhythmias: An Institutional Experience.
Lin AN, Shirai Y, Liang JJ, Chen S, Kochar A, Hyman MC, Santangeli P, Schaller RD, Frankel DS, Arkles JS, Kumareswaran R, Garcia FC, Riley MP, Nazarian S, Lin D, Zado EC, Callans DJ, Marchlinski FE, Supple GE, Dixit S. Lin AN, et al. JACC Clin Electrophysiol. 2020 Oct 26;6(11):1381-1392. doi: 10.1016/j.jacep.2020.06.026. Epub 2020 Sep 16. JACC Clin Electrophysiol. 2020. PMID: 33121667
Oncologic Outcomes Following Transoral Robotic Surgery for Human Papillomavirus-Associated Oropharyngeal Carcinoma in Older Patients.
Parhar HS, Shimunov D, Newman JG, Cannady SB, Rajasekaran K, O' Malley BW Jr, Chalian AA, Rassekh CH, Cohen RB, Lin A, Lukens J, Swisher-McClure S, Bauml J, Aggarwal C, Weinstein GS, Brody RM. Parhar HS, et al. Among authors: lin a. JAMA Otolaryngol Head Neck Surg. 2020 Oct 29. doi: 10.1001/jamaoto.2020.3787. Online ahead of print. JAMA Otolaryngol Head Neck Surg. 2020. PMID: 33119091
Best practice when working with suicidal behaviour and self-harm in primary care: a qualitative exploration of young people's perspectives.
Bellairs-Walsh I, Perry Y, Krysinska K, Byrne SJ, Boland A, Michail M, Lamblin M, Gibson KL, Lin A, Li TY, Hetrick S, Robinson J. Bellairs-Walsh I, et al. Among authors: lin a. BMJ Open. 2020 Oct 28;10(10):e038855. doi: 10.1136/bmjopen-2020-038855. BMJ Open. 2020. PMID: 33115897
Chemical Imaging of Retinal Pigment Epithelium in Frozen Sections of Zebrafish Larvae Using ToF-SIMS.
Van Nuffel S, Ang KC, Lin AY, Cheng KC. Van Nuffel S, et al. Among authors: lin ay. J Am Soc Mass Spectrom. 2020 Oct 28. doi: 10.1021/jasms.0c00300. Online ahead of print. J Am Soc Mass Spectrom. 2020. PMID: 33112610
Cancer occurrence in Turner syndrome and the effect of sex hormone substitution therapy.
Viuff MH, Stochholm K, Lin A, Berglund A, Juul S, Gravholt CH. Viuff MH, et al. Among authors: lin a. Eur J Endocrinol. 2020 Oct 1:EJE-20-0702.R2. doi: 10.1530/EJE-20-0702. Online ahead of print. Eur J Endocrinol. 2020. PMID: 33112259
Pericoronary adipose tissue computed tomography attenuation distinguishes different stages of coronary artery disease: a cross-sectional study.
Lin A, Nerlekar N, Yuvaraj J, Fernandes K, Jiang C, Nicholls SJ, Dey D, Wong DTL. Lin A, et al. Eur Heart J Cardiovasc Imaging. 2020 Oct 27:jeaa224. doi: 10.1093/ehjci/jeaa224. Online ahead of print. Eur Heart J Cardiovasc Imaging. 2020. PMID: 33106867
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