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4,774 results
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Conformational change upon product binding to Klebsiella pneumoniae UDP-glucose dehydrogenase: a possible inhibition mechanism for the key enzyme in polymyxin resistance.
Chen YY, Ko TP, Lin CH, Chen WH, Wang AH. Chen YY, et al. Among authors: lin ch. J Struct Biol. 2011 Sep;175(3):300-10. doi: 10.1016/j.jsb.2011.04.010. Epub 2011 Apr 23. J Struct Biol. 2011. PMID: 21536136
Discovery of picomolar slow tight-binding inhibitors of alpha-fucosidase.
Chang CF, Ho CW, Wu CY, Chao TA, Wong CH, Lin CH. Chang CF, et al. Among authors: lin ch. Chem Biol. 2004 Sep;11(9):1301-6. doi: 10.1016/j.chembiol.2004.07.009. Chem Biol. 2004. PMID: 15380190
Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease.
Shie JJ, Fang JM, Kuo CJ, Kuo TH, Liang PH, Huang HJ, Yang WB, Lin CH, Chen JL, Wu YT, Wong CH. Shie JJ, et al. Among authors: lin ch. J Med Chem. 2005 Jun 30;48(13):4469-73. doi: 10.1021/jm050184y. J Med Chem. 2005. PMID: 15974598
Modular organization of SARS coronavirus nucleocapsid protein.
Chang CK, Sue SC, Yu TH, Hsieh CM, Tsai CK, Chiang YC, Lee SJ, Hsiao HH, Wu WJ, Chang WL, Lin CH, Huang TH. Chang CK, et al. Among authors: lin ch. J Biomed Sci. 2006 Jan;13(1):59-72. doi: 10.1007/s11373-005-9035-9. Epub 2005 Oct 14. J Biomed Sci. 2006. PMID: 16228284 Free PMC article.
Crystal structure of a bifunctional deaminase and reductase from Bacillus subtilis involved in riboflavin biosynthesis.
Chen SC, Chang YC, Lin CH, Lin CH, Liaw SH. Chen SC, et al. Among authors: lin ch, lin ch. J Biol Chem. 2006 Mar 17;281(11):7605-13. doi: 10.1074/jbc.M510254200. Epub 2005 Nov 24. J Biol Chem. 2006. PMID: 16308316
Discovery of different types of inhibition between the human and thermotoga maritima alpha-fucosidases by fuconojirimycin-based derivatives.
Ho CW, Lin YN, Chang CF, Li ST, Wu YT, Wu CY, Chang CF, Liu SW, Li YK, Lin CH. Ho CW, et al. Among authors: lin yn, lin ch. Biochemistry. 2006 May 9;45(18):5695-702. doi: 10.1021/bi052559n. Biochemistry. 2006. PMID: 16669613
Dual binding sites for translocation catalysis by Escherichia coli glutathionylspermidine synthetase.
Pai CH, Chiang BY, Ko TP, Chou CC, Chong CM, Yen FJ, Chen S, Coward JK, Wang AH, Lin CH. Pai CH, et al. Among authors: lin ch. EMBO J. 2006 Dec 13;25(24):5970-82. doi: 10.1038/sj.emboj.7601440. Epub 2006 Nov 23. EMBO J. 2006. PMID: 17124497 Free PMC article.
Structure and mechanism of Helicobacter pylori fucosyltransferase. A basis for lipopolysaccharide variation and inhibitor design.
Sun HY, Lin SW, Ko TP, Pan JF, Liu CL, Lin CN, Wang AH, Lin CH. Sun HY, et al. Among authors: lin sw, lin cn, lin ch. J Biol Chem. 2007 Mar 30;282(13):9973-82. doi: 10.1074/jbc.M610285200. Epub 2007 Jan 24. J Biol Chem. 2007. PMID: 17251184
Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors.
Shao YM, Yang WB, Peng HP, Hsu MF, Tsai KC, Kuo TH, Wang AH, Liang PH, Lin CH, Yang AS, Wong CH. Shao YM, et al. Among authors: lin ch. Chembiochem. 2007 Sep 24;8(14):1654-7. doi: 10.1002/cbic.200700254. Chembiochem. 2007. PMID: 17722121 Free PMC article.
Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease.
Shao YM, Yang WB, Kuo TH, Tsai KC, Lin CH, Yang AS, Liang PH, Wong CH. Shao YM, et al. Among authors: lin ch. Bioorg Med Chem. 2008 Apr 15;16(8):4652-60. doi: 10.1016/j.bmc.2008.02.040. Epub 2008 Feb 15. Bioorg Med Chem. 2008. PMID: 18329272 Free PMC article.
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