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Normalization of lactulose breath testing correlates with symptom improvement in irritable bowel syndrome. a double-blind, randomized, placebo-controlled study.
Pimentel M, Chow EJ, Lin HC. Pimentel M, et al. Among authors: lin hc. Am J Gastroenterol. 2003 Feb;98(2):412-9. doi: 10.1111/j.1572-0241.2003.07234.x. Am J Gastroenterol. 2003. PMID: 12591062 Clinical Trial.
Chronic abdominal pain in children is associated with high prevalence of abnormal microbial fermentation.
Collins BS, Lin HC. Collins BS, et al. Among authors: lin hc. Dig Dis Sci. 2010 Jan;55(1):124-30. doi: 10.1007/s10620-009-1026-7. Dig Dis Sci. 2010. PMID: 19888655
Methane, a gas produced by enteric bacteria, slows intestinal transit and augments small intestinal contractile activity.
Pimentel M, Lin HC, Enayati P, van den Burg B, Lee HR, Chen JH, Park S, Kong Y, Conklin J. Pimentel M, et al. Among authors: lin hc. Am J Physiol Gastrointest Liver Physiol. 2006 Jun;290(6):G1089-95. doi: 10.1152/ajpgi.00574.2004. Epub 2005 Nov 17. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16293652 Clinical Trial.
Increased prevalence of irritable bowel syndrome in patients with gastroesophageal reflux.
Pimentel M, Rossi F, Chow EJ, Ofman J, Fullerton S, Hassard P, Lin HC. Pimentel M, et al. Among authors: lin hc. J Clin Gastroenterol. 2002 Mar;34(3):221-4. doi: 10.1097/00004836-200203000-00004. J Clin Gastroenterol. 2002. PMID: 11873099
Lower frequency of MMC is found in IBS subjects with abnormal lactulose breath test, suggesting bacterial overgrowth.
Pimentel M, Soffer EE, Chow EJ, Kong Y, Lin HC. Pimentel M, et al. Among authors: lin hc. Dig Dis Sci. 2002 Dec;47(12):2639-43. doi: 10.1023/a:1021039032413. Dig Dis Sci. 2002. PMID: 12498278
Bacterial concepts in irritable bowel syndrome.
Lin HC, Pimentel M. Lin HC, et al. Rev Gastroenterol Disord. 2005;5 Suppl 3:S3-9. Rev Gastroenterol Disord. 2005. PMID: 17713456 Review.
Management of small intestinal bacterial overgrowth.
Van Citters GW, Lin HC. Van Citters GW, et al. Among authors: lin hc. Curr Gastroenterol Rep. 2005 Aug;7(4):317-20. doi: 10.1007/s11894-005-0025-x. Curr Gastroenterol Rep. 2005. PMID: 16042917 Review.
Double-blind, placebo-controlled antibiotic treatment study of small intestinal bacterial overgrowth in children with chronic abdominal pain.
Collins BS, Lin HC. Collins BS, et al. Among authors: lin hc. J Pediatr Gastroenterol Nutr. 2011 Apr;52(4):382-6. doi: 10.1097/MPG.0b013e3181effa3b. J Pediatr Gastroenterol Nutr. 2011. PMID: 21240023 Clinical Trial.
Small intestinal bacterial overgrowth: a framework for understanding irritable bowel syndrome.
Lin HC. Lin HC. JAMA. 2004 Aug 18;292(7):852-8. doi: 10.1001/jama.292.7.852. JAMA. 2004. PMID: 15316000 Review.
Eradication of small intestinal bacterial overgrowth reduces symptoms of irritable bowel syndrome.
Pimentel M, Chow EJ, Lin HC. Pimentel M, et al. Among authors: lin hc. Am J Gastroenterol. 2000 Dec;95(12):3503-6. doi: 10.1111/j.1572-0241.2000.03368.x. Am J Gastroenterol. 2000. PMID: 11151884
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