Lin JH - Search Results

1

Inhibition and induction of cytochrome P450 and the clinical implications.

Lin JH, Lu AY. Lin JH, et al. Clin Pharmacokinet. 1998 Nov;35(5):361-90. doi: 10.2165/00003088-199835050-00003. Clin Pharmacokinet. 1998. PMID: 9839089 Review.

2

A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase.

Hazuda DJ, Anthony NJ, Gomez RP, Jolly SM, Wai JS, Zhuang L, Fisher TE, Embrey M, Guare JP Jr, Egbertson MS, Vacca JP, Huff JR, Felock PJ, Witmer MV, Stillmock KA, Danovich R, Grobler J, Miller MD, Espeseth AS, Jin L, Chen IW, Lin JH, Kassahun K, Ellis JD, Wong BK, Xu W, Pearson PG, Schleif WA, Cortese R, Emini E, Summa V, Holloway MK, Young SD. Hazuda DJ, et al. Among authors: lin jh. Proc Natl Acad Sci U S A. 2004 Aug 3;101(31):11233-8. doi: 10.1073/pnas.0402357101. Epub 2004 Jul 26. Proc Natl Acad Sci U S A. 2004. PMID: 15277684 Free PMC article.

3

Evaluation of drug interactions with P-glycoprotein in drug discovery: in vitro assessment of the potential for drug-drug interactions with P-glycoprotein.

Hochman JH, Yamazaki M, Ohe T, Lin JH. Hochman JH, et al. Among authors: lin jh. Curr Drug Metab. 2002 Jun;3(3):257-73. doi: 10.2174/1389200023337559. Curr Drug Metab. 2002. PMID: 12083320 Review.

4

A combinatorial library of indinavir analogues and its in vitro and in vivo studies.

Cheng Y, Rano TA, Huening TT, Zhang F, Lu Z, Schleif WA, Gabryelski L, Olsen DB, Stahlhut M, Kuo LC, Lin JH, Xu X, Jin L, Olah TV, McLoughlin DA, King RC, Chapman KT, Tata JR. Cheng Y, et al. Among authors: lin jh. Bioorg Med Chem Lett. 2002 Feb 25;12(4):529-32. doi: 10.1016/s0960-894x(01)00824-1. Bioorg Med Chem Lett. 2002. PMID: 11844665

5

Mechanistic studies on metabolic interactions between gemfibrozil and statins.

Prueksaritanont T, Zhao JJ, Ma B, Roadcap BA, Tang C, Qiu Y, Liu L, Lin JH, Pearson PG, Baillie TA. Prueksaritanont T, et al. Among authors: lin jh. J Pharmacol Exp Ther. 2002 Jun;301(3):1042-51. doi: 10.1124/jpet.301.3.1042. J Pharmacol Exp Ther. 2002. PMID: 12023536

6

HIV-1 protease inhibitors with picomolar potency against PI-resistant HIV-1 by modification of the P1' substituent.

Duffy JL, Kirk BA, Kevin NJ, Chapman KT, Schleif WA, Olsen DB, Stahlhut M, Rutkowski CA, Kuo LC, Jin L, Lin JH, Emini EA, Tata JR. Duffy JL, et al. Among authors: lin jh. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3323-6. doi: 10.1016/s0960-894x(03)00680-2. Bioorg Med Chem Lett. 2003. PMID: 12951118

7

The design, synthesis and evaluation of novel HIV-1 protease inhibitors with high potency against PI-resistant viral strains.

Zhang F, Chapman KT, Schleif WA, Olsen DB, Stahlhut M, Rutkowski CA, Kuo LC, Jin L, Lin JH, Emini EA, Tata JR. Zhang F, et al. Among authors: lin jh. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2573-6. doi: 10.1016/s0960-894x(03)00474-8. Bioorg Med Chem Lett. 2003. PMID: 12852969

8

HIV protease inhibitors with picomolar potency against PI-Resistant HIV-1 by extension of the P3 substituent.

Duffy JL, Rano TA, Kevin NJ, Chapman KT, Schleif WA, Olsen DB, Stahlhut M, Rutkowski CA, Kuo LC, Jin L, Lin JH, Emini EA, Tata JR. Duffy JL, et al. Among authors: lin jh. Bioorg Med Chem Lett. 2003 Aug 4;13(15):2569-72. doi: 10.1016/s0960-894x(03)00475-x. Bioorg Med Chem Lett. 2003. PMID: 12852968

9

Pharmacokinetic and pharmacodynamic variability: a daunting challenge in drug therapy.

Lin JH. Lin JH. Curr Drug Metab. 2007 Feb;8(2):109-36. doi: 10.2174/138920007779816002. Curr Drug Metab. 2007. PMID: 17305491 Review.

10

Transporter-mediated drug interactions: clinical implications and in vitro assessment.

Lin JH. Lin JH. Expert Opin Drug Metab Toxicol. 2007 Feb;3(1):81-92. doi: 10.1517/17425255.3.1.81. Expert Opin Drug Metab Toxicol. 2007. PMID: 17269896 Review.

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