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5,454 results
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Do age-associated DNA methylation changes increase the risk of malignant transformation?
Wagner W, Weidner CI, Lin Q. Wagner W, et al. Among authors: lin q. Bioessays. 2015 Jan;37(1):20-4. doi: 10.1002/bies.201400063. Epub 2014 Oct 9. Bioessays. 2015. PMID: 25303747 Review.
DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy.
Lin Q, Weidner CI, Costa IG, Marioni RE, Ferreira MR, Deary IJ, Wagner W. Lin Q, et al. Aging (Albany NY). 2016 Feb;8(2):394-401. doi: 10.18632/aging.100908. Aging (Albany NY). 2016. PMID: 26928272 Free PMC article.
Epigenetic Aging Signatures Are Coherently Modified in Cancer.
Lin Q, Wagner W. Lin Q, et al. PLoS Genet. 2015 Jun 25;11(6):e1005334. doi: 10.1371/journal.pgen.1005334. eCollection 2015 Jun. PLoS Genet. 2015. PMID: 26110659 Free PMC article.
Aging of blood can be tracked by DNA methylation changes at just three CpG sites.
Weidner CI, Lin Q, Koch CM, Eisele L, Beier F, Ziegler P, Bauerschlag DO, Jöckel KH, Erbel R, Mühleisen TW, Zenke M, Brümmendorf TH, Wagner W. Weidner CI, et al. Among authors: lin q. Genome Biol. 2014 Feb 3;15(2):R24. doi: 10.1186/gb-2014-15-2-r24. Genome Biol. 2014. PMID: 24490752 Free PMC article.
Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation.
Reinisch A, Etchart N, Thomas D, Hofmann NA, Fruehwirth M, Sinha S, Chan CK, Senarath-Yapa K, Seo EY, Wearda T, Hartwig UF, Beham-Schmid C, Trajanoski S, Lin Q, Wagner W, Dullin C, Alves F, Andreeff M, Weissman IL, Longaker MT, Schallmoser K, Majeti R, Strunk D. Reinisch A, et al. Among authors: lin q. Blood. 2015 Jan 8;125(2):249-60. doi: 10.1182/blood-2014-04-572255. Epub 2014 Nov 18. Blood. 2015. PMID: 25406351 Free PMC article.
Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles.
Shao K, Koch C, Gupta MK, Lin Q, Lenz M, Laufs S, Denecke B, Schmidt M, Linke M, Hennies HC, Hescheler J, Zenke M, Zechner U, Šarić T, Wagner W. Shao K, et al. Among authors: lin q. Mol Ther. 2013 Jan;21(1):240-50. doi: 10.1038/mt.2012.207. Epub 2012 Oct 2. Mol Ther. 2013. PMID: 23032973 Free PMC article.
Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks.
Schellenberg A, Lin Q, Schüler H, Koch CM, Joussen S, Denecke B, Walenda G, Pallua N, Suschek CV, Zenke M, Wagner W. Schellenberg A, et al. Among authors: lin q. Aging (Albany NY). 2011 Sep;3(9):873-88. doi: 10.18632/aging.100391. Aging (Albany NY). 2011. PMID: 22025769 Free PMC article.
ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage.
Perkhofer L, Schmitt A, Romero Carrasco MC, Ihle M, Hampp S, Ruess DA, Hessmann E, Russell R, Lechel A, Azoitei N, Lin Q, Liebau S, Hohwieler M, Bohnenberger H, Lesina M, Algül H, Gieldon L, Schröck E, Gaedcke J, Wagner M, Wiesmüller L, Sipos B, Seufferlein T, Reinhardt HC, Frappart PO, Kleger A. Perkhofer L, et al. Among authors: lin q. Cancer Res. 2017 Oct 15;77(20):5576-5590. doi: 10.1158/0008-5472.CAN-17-0634. Epub 2017 Aug 8. Cancer Res. 2017. PMID: 28790064
Tbx3 fosters pancreatic cancer growth by increased angiogenesis and activin/nodal-dependent induction of stemness.
Perkhofer L, Walter K, Costa IG, Carrasco MC, Eiseler T, Hafner S, Genze F, Zenke M, Bergmann W, Illing A, Hohwieler M, Köhntop R, Lin Q, Holzmann KH, Seufferlein T, Wagner M, Liebau S, Hermann PC, Kleger A, Müller M. Perkhofer L, et al. Among authors: lin q. Stem Cell Res. 2016 Sep;17(2):367-378. doi: 10.1016/j.scr.2016.08.007. Epub 2016 Aug 10. Stem Cell Res. 2016. PMID: 27632063
The polycomb protein Ezh2 impacts on induced pluripotent stem cell generation.
Ding X, Wang X, Sontag S, Qin J, Wanek P, Lin Q, Zenke M. Ding X, et al. Among authors: lin q. Stem Cells Dev. 2014 May 1;23(9):931-40. doi: 10.1089/scd.2013.0267. Epub 2014 Jan 21. Stem Cells Dev. 2014. PMID: 24325319 Free PMC article.
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