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Synthesis and structure-analgesic activity relationships of a novel series of monospirocyclopiperazinium salts (MSPZ).
Lin SW, Sun Q, Ge ZM, Wang X, Ye J, Li RT. Lin SW, et al. Bioorg Med Chem Lett. 2011 Feb 1;21(3):940-3. doi: 10.1016/j.bmcl.2010.12.052. Epub 2010 Dec 21. Bioorg Med Chem Lett. 2011. PMID: 21216141
Discovery of new thieno[2,3-d]pyrimidine and thiazolo[5,4-d]pyrimidine derivatives as orally active phosphoinositide 3-kinase inhibitors.
Sun Y, Fu R, Lin S, Zhang J, Ji M, Zhang Y, Wu D, Zhang K, Tian H, Zhang M, Sheng L, Li Y, Jin J, Chen X, Xu H. Sun Y, et al. Bioorg Med Chem. 2020 Nov 25;29:115890. doi: 10.1016/j.bmc.2020.115890. Online ahead of print. Bioorg Med Chem. 2020. PMID: 33285407
A novel orally active microtubule destabilizing agent S-40 targets the colchicine-binding site and shows potent antitumor activity.
Du T, Lin S, Ji M, Xue N, Liu Y, Zhang Z, Zhang K, Zhang J, Zhang Y, Wang Q, Sheng L, Li Y, Lu D, Chen X, Xu H. Du T, et al. Cancer Lett. 2020 Dec 28;495:22-32. doi: 10.1016/j.canlet.2020.08.040. Epub 2020 Sep 12. Cancer Lett. 2020. PMID: 32931884
Identification of Novel Thiazolo[5,4-b]Pyridine Derivatives as Potent Phosphoinositide 3-Kinase Inhibitors.
Xia L, Zhang Y, Zhang J, Lin S, Zhang K, Tian H, Dong Y, Xu H. Xia L, et al. Molecules. 2020 Oct 12;25(20):4630. doi: 10.3390/molecules25204630. Molecules. 2020. PMID: 33053730 Free PMC article.
Novel cathepsin B-sensitive paclitaxel conjugate: Higher water solubility, better efficacy and lower toxicity.
Liang L, Lin SW, Dai W, Lu JK, Yang TY, Xiang Y, Zhang Y, Li RT, Zhang Q. Liang L, et al. Among authors: lin sw. J Control Release. 2012 Jun 28;160(3):618-29. doi: 10.1016/j.jconrel.2012.02.020. Epub 2012 Mar 3. J Control Release. 2012. PMID: 22410114
A novel PI3K/mTOR dual inhibitor XH002 exhibited robust antitumor activity in NSCLC.
Lv Y, Du T, Ji M, Wang C, Lin S, Xue N, Jin J, Xu H, Chen X. Lv Y, et al. J Drug Target. 2019 Apr;27(4):451-459. doi: 10.1080/1061186X.2018.1542533. Epub 2018 Nov 11. J Drug Target. 2019. PMID: 30381967
Switching the site-selectivity of C-H activation in aryl sulfonamides containing strongly coordinating N-heterocycles.
Dong Y, Zhang X, Chen J, Zou W, Lin S, Xu H. Dong Y, et al. Chem Sci. 2019 Aug 12;10(38):8744-8751. doi: 10.1039/c9sc03691a. eCollection 2019 Oct 14. Chem Sci. 2019. PMID: 31762973 Free PMC article.
Bt354 as a new STAT3 signaling pathway inhibitor against triple negative breast cancer.
Chen Y, Ji M, Zhang S, Xue N, Xu H, Lin S, Chen X. Chen Y, et al. J Drug Target. 2018 Dec;26(10):920-930. doi: 10.1080/1061186X.2018.1452244. Epub 2018 Apr 6. J Drug Target. 2018. PMID: 29595328
Targeted sequencing to identify genetic alterations and prognostic markers in pediatric T-cell acute lymphoblastic leukemia.
Chang YH, Yu CH, Jou ST, Lin CY, Lin KH, Lu MY, Wu KH, Chang HH, Lin DT, Lin SW, Chen HY, Yang YL. Chang YH, et al. Among authors: lin sw. Sci Rep. 2021 Jan 12;11(1):769. doi: 10.1038/s41598-020-80613-6. Sci Rep. 2021. PMID: 33436855 Free PMC article.
Mechanical power during extracorporeal membrane oxygenation and hospital mortality in patients with acute respiratory distress syndrome.
Chiu LC, Lin SW, Chuang LP, Li HH, Liu PH, Tsai FC, Chang CH, Hung CY, Lee CS, Leu SW, Hu HC, Huang CC, Wu HP, Kao KC. Chiu LC, et al. Among authors: lin sw. Crit Care. 2021 Jan 6;25(1):13. doi: 10.1186/s13054-020-03428-x. Crit Care. 2021. PMID: 33407733 Free PMC article.
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