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Type 2 diabetes: new genes, new understanding.
Prokopenko I, McCarthy MI, Lindgren CM. Prokopenko I, et al. Among authors: lindgren cm. Trends Genet. 2008 Dec;24(12):613-21. doi: 10.1016/j.tig.2008.09.004. Epub 2008 Oct 25. Trends Genet. 2008. PMID: 18952314 Free PMC article. Review.
A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.
Frayling TM, Lindgren CM, Chevre JC, Menzel S, Wishart M, Benmezroua Y, Brown A, Evans JC, Rao PS, Dina C, Lecoeur C, Kanninen T, Almgren P, Bulman MP, Wang Y, Mills J, Wright-Pascoe R, Mahtani MM, Prisco F, Costa A, Cognet I, Hansen T, Pedersen O, Ellard S, Tuomi T, Groop LC, Froguel P, Hattersley AT, Vaxillaire M. Frayling TM, et al. Among authors: lindgren cm. Diabetes. 2003 Mar;52(3):872-81. doi: 10.2337/diabetes.52.3.872. Diabetes. 2003. PMID: 12606533
A meta-analysis of four European genome screens (GIFT Consortium) shows evidence for a novel region on chromosome 17p11.2-q22 linked to type 2 diabetes.
Demenais F, Kanninen T, Lindgren CM, Wiltshire S, Gaget S, Dandrieux C, Almgren P, Sjögren M, Hattersley A, Dina C, Tuomi T, McCarthy MI, Froguel P, Groop LC. Demenais F, et al. Among authors: lindgren cm. Hum Mol Genet. 2003 Aug 1;12(15):1865-73. doi: 10.1093/hmg/ddg195. Hum Mol Genet. 2003. PMID: 12874106
A genome wide scan for early onset primary hypertension in Scandinavians.
von Wowern F, Bengtsson K, Lindgren CM, Orho-Melander M, Fyhrquist F, Lindblad U, Råstam L, Forsblom C, Kanninen T, Almgren P, Burri P, Katzman P, Groop L, Hulthén UL, Melander O. von Wowern F, et al. Among authors: lindgren cm. Hum Mol Genet. 2003 Aug 15;12(16):2077-81. doi: 10.1093/hmg/ddg206. Hum Mol Genet. 2003. PMID: 12913078
Common variants in HNF-1 alpha and risk of type 2 diabetes.
Holmkvist J, Cervin C, Lyssenko V, Winckler W, Anevski D, Cilio C, Almgren P, Berglund G, Nilsson P, Tuomi T, Lindgren CM, Altshuler D, Groop L. Holmkvist J, et al. Among authors: lindgren cm. Diabetologia. 2006 Dec;49(12):2882-91. doi: 10.1007/s00125-006-0450-x. Epub 2006 Oct 11. Diabetologia. 2006. PMID: 17033837
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.
Frayling TM, Timpson NJ, Weedon MN, Zeggini E, Freathy RM, Lindgren CM, Perry JR, Elliott KS, Lango H, Rayner NW, Shields B, Harries LW, Barrett JC, Ellard S, Groves CJ, Knight B, Patch AM, Ness AR, Ebrahim S, Lawlor DA, Ring SM, Ben-Shlomo Y, Jarvelin MR, Sovio U, Bennett AJ, Melzer D, Ferrucci L, Loos RJ, Barroso I, Wareham NJ, Karpe F, Owen KR, Cardon LR, Walker M, Hitman GA, Palmer CN, Doney AS, Morris AD, Smith GD, Hattersley AT, McCarthy MI. Frayling TM, et al. Among authors: lindgren cm. Science. 2007 May 11;316(5826):889-94. doi: 10.1126/science.1141634. Epub 2007 Apr 12. Science. 2007. PMID: 17434869 Free PMC article.
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes.
Zeggini E, Weedon MN, Lindgren CM, Frayling TM, Elliott KS, Lango H, Timpson NJ, Perry JR, Rayner NW, Freathy RM, Barrett JC, Shields B, Morris AP, Ellard S, Groves CJ, Harries LW, Marchini JL, Owen KR, Knight B, Cardon LR, Walker M, Hitman GA, Morris AD, Doney AS; Wellcome Trust Case Control Consortium (WTCCC), McCarthy MI, Hattersley AT. Zeggini E, et al. Among authors: lindgren cm. Science. 2007 Jun 1;316(5829):1336-41. doi: 10.1126/science.1142364. Epub 2007 Apr 26. Science. 2007. PMID: 17463249 Free PMC article.
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