Lindquist SL - Search Results

1

HSP90 and the chaperoning of cancer.

Whitesell L, Lindquist SL. Whitesell L, et al. Among authors: lindquist sl. Nat Rev Cancer. 2005 Oct;5(10):761-72. doi: 10.1038/nrc1716. Nat Rev Cancer. 2005. PMID: 16175177 Review.

2

Protein folding sculpting evolutionary change.

Lindquist S. Lindquist S. Cold Spring Harb Symp Quant Biol. 2009;74:103-8. doi: 10.1101/sqb.2009.74.043. Epub 2010 Apr 7. Cold Spring Harb Symp Quant Biol. 2009. PMID: 20375316 Review.

3

Reduced levels of hsp90 compromise steroid receptor action in vivo.

Picard D, Khursheed B, Garabedian MJ, Fortin MG, Lindquist S, Yamamoto KR. Picard D, et al. Nature. 1990 Nov 8;348(6297):166-8. doi: 10.1038/348166a0. Nature. 1990. PMID: 2234079

4

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

Taipale M, Tucker G, Peng J, Krykbaeva I, Lin ZY, Larsen B, Choi H, Berger B, Gingras AC, Lindquist S. Taipale M, et al. Cell. 2014 Jul 17;158(2):434-448. doi: 10.1016/j.cell.2014.05.039. Cell. 2014. PMID: 25036637 Free PMC article.

5

Role of HSP90 in the Regulation of de Novo Purine Biosynthesis.

Pedley AM, Karras GI, Zhang X, Lindquist S, Benkovic SJ. Pedley AM, et al. Biochemistry. 2018 Jun 12;57(23):3217-3221. doi: 10.1021/acs.biochem.8b00140. Epub 2018 Mar 23. Biochemistry. 2018. PMID: 29553718 Free PMC article.

6

HSP90 empowers evolution of resistance to hormonal therapy in human breast cancer models.

Whitesell L, Santagata S, Mendillo ML, Lin NU, Proia DA, Lindquist S. Whitesell L, et al. Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):18297-302. doi: 10.1073/pnas.1421323111. Epub 2014 Dec 8. Proc Natl Acad Sci U S A. 2014. PMID: 25489079 Free PMC article.

7

Chaperones as thermodynamic sensors of drug-target interactions reveal kinase inhibitor specificities in living cells.

Taipale M, Krykbaeva I, Whitesell L, Santagata S, Zhang J, Liu Q, Gray NS, Lindquist S. Taipale M, et al. Nat Biotechnol. 2013 Jul;31(7):630-7. doi: 10.1038/nbt.2620. Epub 2013 Jun 30. Nat Biotechnol. 2013. PMID: 23811600 Free PMC article.

8

Phenotypic diversity and altered environmental plasticity in Arabidopsis thaliana with reduced Hsp90 levels.

Sangster TA, Bahrami A, Wilczek A, Watanabe E, Schellenberg K, McLellan C, Kelley A, Kong SW, Queitsch C, Lindquist S. Sangster TA, et al. PLoS One. 2007 Jul 25;2(7):e648. doi: 10.1371/journal.pone.0000648. PLoS One. 2007. PMID: 17653275 Free PMC article.

9

Inhibiting the transcription factor HSF1 as an anticancer strategy.

Whitesell L, Lindquist S. Whitesell L, et al. Expert Opin Ther Targets. 2009 Apr;13(4):469-78. doi: 10.1517/14728220902832697. Expert Opin Ther Targets. 2009. PMID: 19335068 Review.

10

HSP90 Shapes the Consequences of Human Genetic Variation.

Karras GI, Yi S, Sahni N, Fischer M, Xie J, Vidal M, D'Andrea AD, Whitesell L, Lindquist S. Karras GI, et al. Cell. 2017 Feb 23;168(5):856-866.e12. doi: 10.1016/j.cell.2017.01.023. Epub 2017 Feb 16. Cell. 2017. PMID: 28215707 Free PMC article.

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