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Discovery of INT131: a selective PPARγ modulator that enhances insulin sensitivity.
Taygerly JP, McGee LR, Rubenstein SM, Houze JB, Cushing TD, Li Y, Motani A, Chen JL, Frankmoelle W, Ye G, Learned MR, Jaen J, Miao S, Timmermans PB, Thoolen M, Kearney P, Flygare J, Beckmann H, Weiszmann J, Lindstrom M, Walker N, Liu J, Biermann D, Wang Z, Hagiwara A, Iida T, Aramaki H, Kitao Y, Shinkai H, Furukawa N, Nishiu J, Nakamura M. Taygerly JP, et al. Among authors: lindstrom m. Bioorg Med Chem. 2013 Feb 15;21(4):979-92. doi: 10.1016/j.bmc.2012.11.058. Epub 2012 Dec 10. Bioorg Med Chem. 2013. PMID: 23294830
Identification of potent, noncovalent fatty acid amide hydrolase (FAAH) inhibitors.
Gustin DJ, Ma Z, Min X, Li Y, Hedberg C, Guimaraes C, Porter AC, Lindstrom M, Lester-Zeiner D, Xu G, Carlson TJ, Xiao S, Meleza C, Connors R, Wang Z, Kayser F. Gustin DJ, et al. Among authors: lindstrom m. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2492-6. doi: 10.1016/j.bmcl.2011.02.052. Epub 2011 Feb 17. Bioorg Med Chem Lett. 2011. PMID: 21392988
Discovery of a new class of ghrelin receptor antagonists.
Mihalic JT, Kim YJ, Lizarzaburu M, Chen X, Deignan J, Wanska M, Yu M, Fu J, Chen X, Zhang A, Connors R, Liang L, Lindstrom M, Ma J, Tang L, Dai K, Li L. Mihalic JT, et al. Among authors: lindstrom m. Bioorg Med Chem Lett. 2012 Mar 1;22(5):2046-51. doi: 10.1016/j.bmcl.2012.01.014. Epub 2012 Jan 14. Bioorg Med Chem Lett. 2012. PMID: 22305493
Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity.
Yu M, Lizarzaburu M, Beckmann H, Connors R, Dai K, Haller K, Li C, Liang L, Lindstrom M, Ma J, Motani A, Wanska M, Zhang A, Li L, Medina JC. Yu M, et al. Among authors: lindstrom m. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1758-62. doi: 10.1016/j.bmcl.2010.01.043. Epub 2010 Jan 20. Bioorg Med Chem Lett. 2010. PMID: 20137933
675 results