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Black mamba venom peptides target acid-sensing ion channels to abolish pain.
Diochot S, Baron A, Salinas M, Douguet D, Scarzello S, Dabert-Gay AS, Debayle D, Friend V, Alloui A, Lazdunski M, Lingueglia E. Diochot S, et al. Among authors: lingueglia e. Nature. 2012 Oct 25;490(7421):552-5. doi: 10.1038/nature11494. Epub 2012 Oct 3. Nature. 2012. PMID: 23034652
Non-acidic activation of pain-related Acid-Sensing Ion Channel 3 by lipids.
Marra S, Ferru-Clément R, Breuil V, Delaunay A, Christin M, Friend V, Sebille S, Cognard C, Ferreira T, Roux C, Euller-Ziegler L, Noel J, Lingueglia E, Deval E. Marra S, et al. Among authors: lingueglia e. EMBO J. 2016 Feb 15;35(4):414-28. doi: 10.15252/embj.201592335. Epub 2016 Jan 15. EMBO J. 2016. PMID: 26772186 Free PMC article.
Mambalgin-1 Pain-relieving Peptide, Stepwise Solid-phase Synthesis, Crystal Structure, and Functional Domain for Acid-sensing Ion Channel 1a Inhibition.
Mourier G, Salinas M, Kessler P, Stura EA, Leblanc M, Tepshi L, Besson T, Diochot S, Baron A, Douguet D, Lingueglia E, Servent D. Mourier G, et al. Among authors: lingueglia e. J Biol Chem. 2016 Feb 5;291(6):2616-29. doi: 10.1074/jbc.M115.702373. Epub 2015 Dec 17. J Biol Chem. 2016. PMID: 26680001 Free PMC article.
Acid-Sensing Ion Channels in the nervous system. Foreword.
Lingueglia E, Lazdunski M. Lingueglia E, et al. Neuropharmacology. 2015 Jul;94:1. doi: 10.1016/j.neuropharm.2015.03.011. Epub 2015 Mar 24. Neuropharmacology. 2015. PMID: 25813612 No abstract available.
[Acid-Sensing Ion Channels (ASICs) in pain].
Lingueglia E. Lingueglia E. Biol Aujourdhui. 2014;208(1):13-20. doi: 10.1051/jbio/2014001. Epub 2014 Jun 23. Biol Aujourdhui. 2014. PMID: 24948015 Review. French.
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