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Inflammatory macrophages in pancreatic acinar cell metaplasia and initiation of pancreatic cancer.
Liou GY, Storz P. Liou GY, et al. Oncoscience. 2015 Mar 28;2(3):247-51. doi: 10.18632/oncoscience.151. eCollection 2015. Oncoscience. 2015. PMID: 25897428 Free PMC article.
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs.
Liou GY, Döppler H, Necela B, Krishna M, Crawford HC, Raimondo M, Storz P. Liou GY, et al. J Cell Biol. 2013 Aug 5;202(3):563-77. doi: 10.1083/jcb.201301001. J Cell Biol. 2013. PMID: 23918941 Free PMC article.
Pomalidomide Alters Pancreatic Macrophage Populations to Generate an Immune-Responsive Environment at Precancerous and Cancerous Lesions.
Bastea LI, Liou GY, Pandey V, Fleming AK, von Roemeling CA, Doeppler H, Li Z, Qiu Y, Edenfield B, Copland JA, Tun HW, Storz P. Bastea LI, et al. Among authors: liou gy. Cancer Res. 2019 Apr 1;79(7):1535-1548. doi: 10.1158/0008-5472.CAN-18-1153. Epub 2019 Jan 29. Cancer Res. 2019. PMID: 30696657 Free PMC article.
Paracrine Secretion of Transforming Growth Factor β by Ductal Cells Promotes Acinar-to-Ductal Metaplasia in Cultured Human Exocrine Pancreas Tissues.
Akanuma N, Liu J, Liou GY, Yin X, Bejar KR, Liu C, Sun LZ, Storz P, Wang P. Akanuma N, et al. Among authors: liou gy. Pancreas. 2017 Oct;46(9):1202-1207. doi: 10.1097/MPA.0000000000000913. Pancreas. 2017. PMID: 28902792 Free PMC article.
Glycogen synthase kinase-3β ablation limits pancreatitis-induced acinar-to-ductal metaplasia.
Ding L, Liou GY, Schmitt DM, Storz P, Zhang JS, Billadeau DD. Ding L, et al. Among authors: liou gy. J Pathol. 2017 Sep;243(1):65-77. doi: 10.1002/path.4928. Epub 2017 Jul 27. J Pathol. 2017. PMID: 28639695 Free PMC article.
The Presence of Interleukin-13 at Pancreatic ADM/PanIN Lesions Alters Macrophage Populations and Mediates Pancreatic Tumorigenesis.
Liou GY, Bastea L, Fleming A, Döppler H, Edenfield BH, Dawson DW, Zhang L, Bardeesy N, Storz P. Liou GY, et al. Cell Rep. 2017 May 16;19(7):1322-1333. doi: 10.1016/j.celrep.2017.04.052. Cell Rep. 2017. PMID: 28514653 Free PMC article.
A bright future for protein kinase D1 as a drug target to prevent or treat pancreatic cancer.
Liou GY, Storz P, Leitges M. Liou GY, et al. Mol Cell Oncol. 2015 Dec 10;3(1):e1035477. doi: 10.1080/23723556.2015.1035477. eCollection 2016 Jan. Mol Cell Oncol. 2015. PMID: 27308552 Free PMC article.
Mutant KRas-Induced Mitochondrial Oxidative Stress in Acinar Cells Upregulates EGFR Signaling to Drive Formation of Pancreatic Precancerous Lesions.
Liou GY, Döppler H, DelGiorno KE, Zhang L, Leitges M, Crawford HC, Murphy MP, Storz P. Liou GY, et al. Cell Rep. 2016 Mar 15;14(10):2325-36. doi: 10.1016/j.celrep.2016.02.029. Epub 2016 Mar 3. Cell Rep. 2016. PMID: 26947075 Free PMC article.
NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation.
Hessmann E, Zhang JS, Chen NM, Hasselluhn M, Liou GY, Storz P, Ellenrieder V, Billadeau DD, Koenig A. Hessmann E, et al. Among authors: liou gy. Stem Cells Int. 2016;2016:5272498. doi: 10.1155/2016/5272498. Epub 2015 Nov 30. Stem Cells Int. 2016. PMID: 26697077 Free PMC article.
Protein kinase D enzymes: novel kinase targets in pancreatic cancer.
Liou GY, Storz P. Liou GY, et al. Expert Rev Gastroenterol Hepatol. 2015;9(9):1143-6. doi: 10.1586/17474124.2015.1069706. Epub 2015 Jul 17. Expert Rev Gastroenterol Hepatol. 2015. PMID: 26174103 Free PMC article. Review.
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