Lipid biology of the podocyte--new perspectives offer new opportunities.
Nat Rev Nephrol. 2014.
PMID: 24861084
Free PMC article.
Review.
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Lipid biology of the podocyte--new perspectives offer new opportunities.
Nat Rev Nephrol. 2014 Jul;10(7):379-88. doi: 10.1038/nrneph.2014.87. Epub 2014 May 27.
Nat Rev Nephrol. 2014.
PMID: 24861084
Free PMC article.
Review.
In the past 15 years, major advances have been made in understanding the role of lipids in podocyte biology. First, susceptibility to focal segmental glomerulosclerosis (FSGS) and glomerular disease is associated with an APOL1 sequence variant, is expressed in podoc …
In the past 15 years, major advances have been made in understanding the role of lipids in podocyte biology. First, susceptibi …
Molecular Modeling for Nanomaterial-Biology Interactions: Opportunities, Challenges, and Perspectives.
Front Bioeng Biotechnol. 2019 Oct 17;7:268. doi: 10.3389/fbioe.2019.00268. eCollection 2019.
Front Bioeng Biotechnol. 2019.
PMID: 31681746
Free PMC article.
Review.
The protein corona and the resulting structural changes experienced by adsorbed proteins can lead to substantial deviations from the expected cellular uptake as well as biological responses such as NP aggregation and NP-induced protein fibrillation, NP interference with enzymatic …
The protein corona and the resulting structural changes experienced by adsorbed proteins can lead to substantial deviations from the expecte …
The impact of histone lactylation on the tumor microenvironment and metabolic pathways and its potential in cancer therapy.
Genes Genomics. 2024 Sep;46(9):991-1011. doi: 10.1007/s13258-024-01554-2. Epub 2024 Aug 10.
Genes Genomics. 2024.
PMID: 39127851
Review.
Various cell types within the TME, including T cells and macrophages, were found to regulate tumor growth and immune escape mechanisms through lactylation. CONCLUSION: Histone lactylation offers a novel perspective on tumor metabolism and its role in cancer developm …
Various cell types within the TME, including T cells and macrophages, were found to regulate tumor growth and immune escape mechanisms throu …
G Protein-Coupled Receptor Pharmacology-Insights from Mass Spectrometry.
Pharmacol Rev. 2023 May;75(3):397-415. doi: 10.1124/pharmrev.120.000237. Epub 2023 Mar 14.
Pharmacol Rev. 2023.
PMID: 36918259
Free article.
Review.
The ability of mass spectrometry (MS) to observe both the binding of ligand molecules, such as lipids, ions, or drugs, and their impact on interaction with transducers provides an exciting opportunity to probe many aspects that are difficult to track directly in cel …
The ability of mass spectrometry (MS) to observe both the binding of ligand molecules, such as lipids, ions, or drugs, and their impa …
Lipid Mediated Regulation of Adult Stem Cell Behavior.
Front Cell Dev Biol. 2020 Feb 28;8:115. doi: 10.3389/fcell.2020.00115. eCollection 2020.
Front Cell Dev Biol. 2020.
PMID: 32185173
Free PMC article.
Review.
Therefore, understanding how lipid metabolism affects stem cell behavior offers promising perspectives for the development of novel approaches to control stem cell behavior either in vitro or in patients, by modulating lipid metabolic pathways pharmaco …
Therefore, understanding how lipid metabolism affects stem cell behavior offers promising perspectives for the developm …
The dark side of lipid metabolism in prostate and renal carcinoma: novel insights into molecular diagnostic and biomarker discovery.
Expert Rev Mol Diagn. 2023 Apr;23(4):297-313. doi: 10.1080/14737159.2023.2195553. Epub 2023 Mar 28.
Expert Rev Mol Diagn. 2023.
PMID: 36960789
Review.
The increased intracellular accumulation of different classes of lipids in renal cell carcinoma (RCC) and prostate cancer (PCa) cells may be caused by elevated absorption or by increased de novo lipogenesis as a consequence of lipid metabolism reprogramming. ...Trac …
The increased intracellular accumulation of different classes of lipids in renal cell carcinoma (RCC) and prostate cancer (PCa) cells …
Metabolomics in endometriosis: challenges and perspectives for future studies.
Reprod Fertil. 2021 May 6;2(2):R35-R50. doi: 10.1530/RAF-20-0047. eCollection 2021 Apr.
Reprod Fertil. 2021.
PMID: 35128453
Free PMC article.
Review.
Reported metabolites included amino acids, lipids, organic acids, and other organic compounds. Differences in methods, analytical techniques, and the presence of confounding factors can interfere with results and interpretation of data. ...Biomarkers include cell growth, c …
Reported metabolites included amino acids, lipids, organic acids, and other organic compounds. Differences in methods, analytical tec …
Challenges and opportunities in exosome research-Perspectives from biology, engineering, and cancer therapy.
APL Bioeng. 2019 Mar 27;3(1):011503. doi: 10.1063/1.5087122. eCollection 2019 Mar.
APL Bioeng. 2019.
PMID: 31069333
Free PMC article.
Review.
Exosomes are small ( 30-140 nm) lipid bilayer-enclosed particles of endosomal origin. They are a subset of extracellular vesicles (EVs) that are secreted by most cell types. ...As a result, investigation of exosome cargo contents could offer opportunities for …
Exosomes are small ( 30-140 nm) lipid bilayer-enclosed particles of endosomal origin. They are a subset of extracellular vesicles (EV …
Lipid droplets and liver disease: from basic biology to clinical implications.
Nat Rev Gastroenterol Hepatol. 2017 Jun;14(6):343-355. doi: 10.1038/nrgastro.2017.32. Epub 2017 Apr 21.
Nat Rev Gastroenterol Hepatol. 2017.
PMID: 28428634
Free PMC article.
Review.
Here, we review the latest insights into the biology of lipid droplets and their role in maintaining lipid homeostasis in the liver. We also offer a perspective of liver diseases that feature lipid accumulation in these lipid stora …
Here, we review the latest insights into the biology of lipid droplets and their role in maintaining lipid homeostasis …
Myristate and the ecology of AM fungi: significance, opportunities, applications and challenges.
New Phytol. 2020 Sep;227(6):1610-1614. doi: 10.1111/nph.16527. Epub 2020 Apr 9.
New Phytol. 2020.
PMID: 32147825
Free article.
In addition, myristate may open up several avenues from a more applied perspective, including improved fungal culture and supplementation of AM fungi or inoculum in the field. We here map these potential opportunities, and additionally offer thoughts on poten …
In addition, myristate may open up several avenues from a more applied perspective, including improved fungal culture and supplementa …
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