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Table representation of search results timeline featuring number of search results per year.

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1951 1
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1958 32
1959 35
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1963 54
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1968 29
1969 36
1970 35
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1972 40
1973 28
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1982 28
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1988 22
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1992 47
1993 45
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1995 63
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1999 116
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2002 128
2003 154
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Page 1
Insights on the Use of α-Lipoic Acid for Therapeutic Purposes.
Salehi B, Berkay Yılmaz Y, Antika G, Boyunegmez Tumer T, Fawzi Mahomoodally M, Lobine D, Akram M, Riaz M, Capanoglu E, Sharopov F, Martins N, Cho WC, Sharifi-Rad J. Salehi B, et al. Biomolecules. 2019 Aug 9;9(8):356. doi: 10.3390/biom9080356. Biomolecules. 2019. PMID: 31405030 Free PMC article. Review.
alpha-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. ...
alpha-lipoic acid (ALA, thioctic acid) is an organosulfur component produced from plants, animals, and humans. . …
Lipoic acid metabolism and mitochondrial redox regulation.
Solmonson A, DeBerardinis RJ. Solmonson A, et al. J Biol Chem. 2018 May 18;293(20):7522-7530. doi: 10.1074/jbc.TM117.000259. Epub 2017 Nov 30. J Biol Chem. 2018. PMID: 29191830 Free PMC article. Review.
Lipoic acid is an essential cofactor for mitochondrial metabolism and is synthesized de novo using intermediates from mitochondrial fatty-acid synthesis type II, S-adenosylmethionine and iron-sulfur clusters. ...Many of these dehydrogenases are regulated by r …
Lipoic acid is an essential cofactor for mitochondrial metabolism and is synthesized de novo using intermediates from mitochon …
alpha-Lipoic acid as a biological antioxidant.
Packer L, Witt EH, Tritschler HJ. Packer L, et al. Free Radic Biol Med. 1995 Aug;19(2):227-50. doi: 10.1016/0891-5849(95)00017-r. Free Radic Biol Med. 1995. PMID: 7649494 Review.
alpha-Lipoic acid, which plays an essential role in mitochondrial dehydrogenase reactions, has recently gained considerable attention as an antioxidant. ...In addition to its antioxidant activities, dihydrolipoate may exert prooxidant actions through reduction of ir …
alpha-Lipoic acid, which plays an essential role in mitochondrial dehydrogenase reactions, has recently gained considerable at …
Efficacy of α-lipoic acid in diabetic neuropathy.
Papanas N, Ziegler D. Papanas N, et al. Expert Opin Pharmacother. 2014 Dec;15(18):2721-31. doi: 10.1517/14656566.2014.972935. Epub 2014 Nov 10. Expert Opin Pharmacother. 2014. PMID: 25381809 Review.
AREAS COVERED: The objective of this review is assessment of efficacy and safety of alpha lipoic acid (ALA, also thioctic acid) in pathogenesis-oriented treatment of diabetic neuropathy. ...
AREAS COVERED: The objective of this review is assessment of efficacy and safety of alpha lipoic acid (ALA, also thioctic …
Alpha-lipoic acid: molecular mechanisms and therapeutic potential in diabetes.
Rochette L, Ghibu S, Muresan A, Vergely C. Rochette L, et al. Can J Physiol Pharmacol. 2015 Dec;93(12):1021-7. doi: 10.1139/cjpp-2014-0353. Epub 2015 Sep 25. Can J Physiol Pharmacol. 2015. PMID: 26406389 Review.
It is widely accepted that diabetes impairs endothelial nitric oxide synthase (eNOS) activity and increases the production of ROS, thus resulting in diminished NO bioavailability and increased oxidative stress. Alpha-lipoic acid (LA) possesses beneficial effects bot …
It is widely accepted that diabetes impairs endothelial nitric oxide synthase (eNOS) activity and increases the production of ROS, thus resu …
Effect of α-lipoic acid on symptoms and quality of life in patients with painful diabetic neuropathy.
Agathos E, Tentolouris A, Eleftheriadou I, Katsaouni P, Nemtzas I, Petrou A, Papanikolaou C, Tentolouris N. Agathos E, et al. J Int Med Res. 2018 May;46(5):1779-1790. doi: 10.1177/0300060518756540. Epub 2018 Mar 8. J Int Med Res. 2018. PMID: 29517942 Free PMC article. Clinical Trial.
Objective To examine the effect of alpha-lipoic acid on neuropathic symptoms in patients with diabetic neuropathy (DN). ...Conclusions A-lipoic acid administration was associated with reduced neuropathic symptoms and triglycerides, and improved quality …
Objective To examine the effect of alpha-lipoic acid on neuropathic symptoms in patients with diabetic neuropathy (DN). ...Con …
Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential.
Shay KP, Moreau RF, Smith EJ, Smith AR, Hagen TM. Shay KP, et al. Biochim Biophys Acta. 2009 Oct;1790(10):1149-60. doi: 10.1016/j.bbagen.2009.07.026. Epub 2009 Aug 4. Biochim Biophys Acta. 2009. PMID: 19664690 Free PMC article. Review.
Alpha-lipoic acid (LA) has become a common ingredient in multivitamin formulas, anti-aging supplements, and even pet food. ...Though LA has long been touted as an antioxidant, it has also been shown to improve glucose and ascorbate handling, increase eNOS activity, …
Alpha-lipoic acid (LA) has become a common ingredient in multivitamin formulas, anti-aging supplements, and even pet food. ... …
Lipoic acid. Kinetics and pluripotent biological properties and derivatives.
Theodosis-Nobelos P, Papagiouvannis G, Tziona P, Rekka EA. Theodosis-Nobelos P, et al. Mol Biol Rep. 2021 Sep;48(9):6539-6550. doi: 10.1007/s11033-021-06643-z. Epub 2021 Aug 22. Mol Biol Rep. 2021. PMID: 34420148 Review.
Lipoic acid (LA) is globally known and its supplements are widely used. ...Furthermore, the safety and the toxicological profile of the compound are commented, together with its stability issues. Mechanisms of lipoic acid intervention in the human body …
Lipoic acid (LA) is globally known and its supplements are widely used. ...Furthermore, the safety and the toxicological profi …
Role of lipoic acid in multiple sclerosis.
Xie H, Yang X, Cao Y, Long X, Shang H, Jia Z. Xie H, et al. CNS Neurosci Ther. 2022 Mar;28(3):319-331. doi: 10.1111/cns.13793. Epub 2021 Dec 28. CNS Neurosci Ther. 2022. PMID: 34964271 Free PMC article. Review.
Lipoic acid (LA) is an endogenous antioxidant that exists widely in nature. ...
Lipoic acid (LA) is an endogenous antioxidant that exists widely in nature. ...
The Immunomodulatory Effect of Alpha-Lipoic Acid in Autoimmune Diseases.
Liu W, Shi LJ, Li SG. Liu W, et al. Biomed Res Int. 2019 Mar 20;2019:8086257. doi: 10.1155/2019/8086257. eCollection 2019. Biomed Res Int. 2019. PMID: 31016198 Free PMC article. Review.
alphalpha-lipoic acid is a naturally occurring antioxidant in human body and has been widely used as an antioxidant clinically. Accumulating evidences suggested that alpha-lipoic acid might have immunomodulatory effects on both adaptive and innate immu …
alphalpha-lipoic acid is a naturally occurring antioxidant in human body and has been widely used as an antioxidant clinically …
6,780 results