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Anxioselective anxiolytics: can less be more?
Basile AS, Lippa AS, Skolnick P. Basile AS, et al. Among authors: lippa as. Eur J Pharmacol. 2004 Oct 1;500(1-3):441-51. doi: 10.1016/j.ejphar.2004.07.043. Eur J Pharmacol. 2004. PMID: 15464051 Review.
Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator.
Lippa A, Czobor P, Stark J, Beer B, Kostakis E, Gravielle M, Bandyopadhyay S, Russek SJ, Gibbs TT, Farb DH, Skolnick P. Lippa A, et al. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7380-5. doi: 10.1073/pnas.0502579102. Epub 2005 May 3. Proc Natl Acad Sci U S A. 2005. PMID: 15870187 Free PMC article. Clinical Trial.
The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors.
Popik P, Kostakis E, Krawczyk M, Nowak G, Szewczyk B, Krieter P, Chen Z, Russek SJ, Gibbs TT, Farb DH, Skolnick P, Lippa AS, Basile AS. Popik P, et al. Among authors: lippa as. J Pharmacol Exp Ther. 2006 Dec;319(3):1244-52. doi: 10.1124/jpet.106.107201. Epub 2006 Sep 13. J Pharmacol Exp Ther. 2006. PMID: 16971504
Introduction. Overview of citalopram.
Lippa AS, Beer B, Cancro R. Lippa AS, et al. J Clin Psychopharmacol. 1999 Oct;19(5 Suppl 1):1S-3S. doi: 10.1097/00004714-199910001-00001. J Clin Psychopharmacol. 1999. PMID: 10507504 No abstract available.
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