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The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice.
List EO, Berryman DE, Funk K, Gosney ES, Jara A, Kelder B, Wang X, Kutz L, Troike K, Lozier N, Mikula V, Lubbers ER, Zhang H, Vesel C, Junnila RK, Frank SJ, Masternak MM, Bartke A, Kopchick JJ. List EO, et al. Mol Endocrinol. 2013 Mar;27(3):524-35. doi: 10.1210/me.2012-1330. Epub 2013 Jan 24. Mol Endocrinol. 2013. PMID: 23349524 Free PMC article.
GHR-/- mice also have elevated levels of leptin, resistin, and adiponectin, compared with controls leading some to suggest that GH may negatively regulate certain adipokines. To help clarify the role that GH exerts specifically on adipose tissue in vivo, we …
GHR-/- mice also have elevated levels of leptin, resistin, and adiponectin, compared with controls leading some to suggest that GH may negat …
Effects of canagliflozin versus glimepiride on adipokines and inflammatory biomarkers in type 2 diabetes.
Garvey WT, Van Gaal L, Leiter LA, Vijapurkar U, List J, Cuddihy R, Ren J, Davies MJ. Garvey WT, et al. Metabolism. 2018 Aug;85:32-37. doi: 10.1016/j.metabol.2018.02.002. Epub 2018 Feb 13. Metabolism. 2018. PMID: 29452178 Free article. Clinical Trial.
This post hoc, exploratory analysis assessed the effects of canagliflozin versus glimepiride on select adipokines, inflammatory biomarkers, and chemokines. METHODS: Changes from baseline to Week 52 in serum leptin, adiponectin, IL-6, TNFalpha, CRP, PAI-1, VCAM-1, an …
This post hoc, exploratory analysis assessed the effects of canagliflozin versus glimepiride on select adipokines, inflammator …
Identification and validation of novel adipokines released from primary human adipocytes.
Lehr S, Hartwig S, Lamers D, Famulla S, Müller S, Hanisch FG, Cuvelier C, Ruige J, Eckardt K, Ouwens DM, Sell H, Eckel J. Lehr S, et al. Mol Cell Proteomics. 2012 Jan;11(1):M111.010504. doi: 10.1074/mcp.M111.010504. Epub 2011 Sep 26. Mol Cell Proteomics. 2012. PMID: 21947364 Free PMC article.
Adipose tissue is a major endocrine organ, releasing signaling and mediator proteins, termed adipokines, via which adipose tissue communicates with other organs. Expansion of adipose tissue in obesity alters adipokine sec …
Adipose tissue is a major endocrine organ, releasing signaling and mediator proteins, termed adipokines, via which a …
Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles.
List EO, Berryman DE, Funk K, Jara A, Kelder B, Wang F, Stout MB, Zhi X, Sun L, White TA, LeBrasseur NK, Pirtskhalava T, Tchkonia T, Jensen EA, Zhang W, Masternak MM, Kirkland JL, Miller RA, Bartke A, Kopchick JJ. List EO, et al. Endocrinology. 2014 May;155(5):1793-805. doi: 10.1210/en.2013-2086. Epub 2014 Feb 11. Endocrinology. 2014. PMID: 24517230 Free PMC article.
Local IGF-I mRNA levels were significantly increased in skeletal muscle and select adipose tissue depots. Grip strength was increased in LiGHRKO mice. Finally, circulating levels of leptin, resistin, and adiponectin were increased in LiGHRKO mice. ...Furtherm …
Local IGF-I mRNA levels were significantly increased in skeletal muscle and select adipose tissue depots. Grip strength …