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Neuroprotective effect of Lithospermum officinale callus extract on inflamed primary microglial cells.
Kheyrollah M, Farhadpour M, Sabouni F, Haghbeen K. Kheyrollah M, et al. Curr Pharm Biotechnol. 2023 Aug 16. doi: 10.2174/1389201024666230816154639. Online ahead of print. Curr Pharm Biotechnol. 2023. PMID: 37587806
They produce secondary metabolites with antioxidant, antimicrobial and/or anti-cancer effects. Lithospermum officinale, known as European stone seed, is a famous medicinal herb. ...RESULTS: Methanolic extract of the 17-day-old callus of L. officinale exhibite …
They produce secondary metabolites with antioxidant, antimicrobial and/or anti-cancer effects. Lithospermum officinale, known …
Root-associated bacteria modulate the specialised metabolome of Lithospermum officinale L.
Varela Alonso A, Naranjo HD, Rat A, Rodić N, Nannou CI, Lambropoulou DA, Assimopoulou AN, Declerck S, Rödel P, Schneider C, Willems A. Varela Alonso A, et al. Front Plant Sci. 2022 Aug 30;13:908669. doi: 10.3389/fpls.2022.908669. eCollection 2022. Front Plant Sci. 2022. PMID: 36110355 Free PMC article.
Here we assessed, for the first time, the effects of bacteria on the modulation of SM production in the medicinal plant Lithospermum officinale (Boraginaceae family) with a focus on the naphthoquinones alkannin/shikonin and their derivatives (A/Sd). ...This work hig …
Here we assessed, for the first time, the effects of bacteria on the modulation of SM production in the medicinal plant Lithospermum
Development and Validation of a Method to Quantify Flavonoids in Leaves of Lithospermum officinale (Boraginaceae).
Adamtsevich NY, Zakrzheuskaya YI, Feskova EV, Leontiev VN, Titok VV. Adamtsevich NY, et al. Dokl Biol Sci. 2023 Oct;512(1):354-359. doi: 10.1134/S001249662370062X. Epub 2023 Dec 12. Dokl Biol Sci. 2023. PMID: 38087026
The common gromwell Lithospermum officinale L. is a valuable medicinal plant that has been used in traditional medicine since ancient times. ...The flavonoid content expressed in terms of rutin was found to exceed 2% of the absolutely dry weight in L. officinale
The common gromwell Lithospermum officinale L. is a valuable medicinal plant that has been used in traditional medicine since …
Transcriptional dynamics of Chitinophaga sp. strain R-73072-mediated alkannin/shikonin biosynthesis in Lithospermum officinale.
Ahmad M, Varela Alonso A, Koletti AE, Assimopoulou AN, Declerck S, Schneider C, Molin EM. Ahmad M, et al. Front Microbiol. 2022 Aug 22;13:978021. doi: 10.3389/fmicb.2022.978021. eCollection 2022. Front Microbiol. 2022. PMID: 36071973 Free PMC article.
To gain insight into these mechanisms, we analyzed the molecular responses of Lithospermum officinale, an alkannin/shikonin producing member of Boraginaceae, to inoculation with R-73072 in a gnotobiotic system using comparative transcriptomics and targeted metabolit …
To gain insight into these mechanisms, we analyzed the molecular responses of Lithospermum officinale, an alkannin/shikonin pr …
Dynamics of alkannin/shikonin biosynthesis in response to jasmonate and salicylic acid in Lithospermum officinale.
Ahmad M, Varela Alonso A, Koletti AE, Rodić N, Reichelt M, Rödel P, Assimopoulou AN, Paun O, Declerck S, Schneider C, Molin EM. Ahmad M, et al. Sci Rep. 2022 Oct 12;12(1):17093. doi: 10.1038/s41598-022-21322-0. Sci Rep. 2022. PMID: 36224205 Free PMC article.
In the present study, we generated the first comprehensive transcriptomic dataset and metabolite profiles of Lithospermum officinale plants treated with methyl jasmonate and salicylic acid to shed light on the underlying mechanisms. Our results highlight the diverse …
In the present study, we generated the first comprehensive transcriptomic dataset and metabolite profiles of Lithospermum officina
The Effect of Lithospermum officinale, Silver Sulfadiazine and Alpha Ointments in Healing of Burn Wound Injuries in Rat.
Mohtasham Amiri Z, Tanideh N, Seddighi A, Mokhtari M, Amini M, Shakouri Partovi A, Manafi A, Hashemi SS, Mehrabani D. Mohtasham Amiri Z, et al. World J Plast Surg. 2017 Sep;6(3):313-318. World J Plast Surg. 2017. PMID: 29218280 Free PMC article.
BACKGROUND: Burn is the most devastating condition in emergency medicine leading to chronic disabilities. This study aimed to compare the effect of Lithospermum officinale, silver sulfadiazine and alpha ointments on healing of burn wounds in rat. ...The number of ma …
BACKGROUND: Burn is the most devastating condition in emergency medicine leading to chronic disabilities. This study aimed to compare the ef …
Pyrrolizidine Alkaloids-Free Extract from the Cell Culture of Lithospermum officinale with High Antioxidant Capacity.
Khosravi E, Mousavi A, Farhadpour M, Ghashghaie J, Ghanati F, Haghbeen K. Khosravi E, et al. Appl Biochem Biotechnol. 2019 Mar;187(3):744-752. doi: 10.1007/s12010-018-2830-3. Epub 2018 Jul 27. Appl Biochem Biotechnol. 2019. PMID: 30054862
The benefits of Lithospermum officinale has encouraged people to continue using its extract (CAS 90063-58-4) in both medicinal and cosmetic industries despite the fact that chemical analysis confirms the presence of pyrrolizidine alkaloids (PAs) in the extract. Whil …
The benefits of Lithospermum officinale has encouraged people to continue using its extract (CAS 90063-58-4) in both medicinal …
Urolithiasis and phytotherapy.
Grases F, Melero G, Costa-Bauzá A, Prieto R, March JG. Grases F, et al. Int Urol Nephrol. 1994;26(5):507-11. doi: 10.1007/BF02767650. Int Urol Nephrol. 1994. PMID: 7860196
The effects of seven plants with suspected application to prevent and treat stone kidney formation (Verbena officinalis, Lithospermum officinale, Taraxacum officinale, Equisetum arvense, Arctostaphylos uva-ursi, Arctium lappa and Silene saxifraga) have been s …
The effects of seven plants with suspected application to prevent and treat stone kidney formation (Verbena officinalis, Lithospermum
De Novo Transcriptome Assembly and Characterization of Lithospermum officinale to Discover Putative Genes Involved in Specialized Metabolites Biosynthesis.
Rai A, Nakaya T, Shimizu Y, Rai M, Nakamura M, Suzuki H, Saito K, Yamazaki M. Rai A, et al. Planta Med. 2018 Aug;84(12-13):920-934. doi: 10.1055/a-0630-5925. Epub 2018 May 29. Planta Med. 2018. PMID: 29843181
Lithospermum officinale is a valuable source of bioactive metabolites with medicinal and industrial values. ...Using over 4Gbps of RNA-sequencing datasets, we obtained de novo transcriptome assembly of L. officinale, consisting of 77,047 unigenes with assembl
Lithospermum officinale is a valuable source of bioactive metabolites with medicinal and industrial values. ...Using over 4Gbp
48 results