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Patient-iPSC-Derived Kidney Organoids Show Functional Validation of a Ciliopathic Renal Phenotype and Reveal Underlying Pathogenetic Mechanisms.
Forbes TA, Howden SE, Lawlor K, Phipson B, Maksimovic J, Hale L, Wilson S, Quinlan C, Ho G, Holman K, Bennetts B, Crawford J, Trnka P, Oshlack A, Patel C, Mallett A, Simons C, Little MH. Forbes TA, et al. Among authors: little mh. Am J Hum Genet. 2018 May 3;102(5):816-831. doi: 10.1016/j.ajhg.2018.03.014. Epub 2018 Apr 26. Am J Hum Genet. 2018. PMID: 29706353 Free PMC article.
Reprogramming somatic cells to a kidney fate.
Takasato M, Vanslambrouck JM, Little MH. Takasato M, et al. Among authors: little mh. Semin Nephrol. 2014 Jul;34(4):462-80. doi: 10.1016/j.semnephrol.2014.06.012. Epub 2014 Jun 13. Semin Nephrol. 2014. PMID: 25217274 Review.
Direct transcriptional reprogramming to nephron progenitors.
Vanslambrouck JM, Little MH. Vanslambrouck JM, et al. Among authors: little mh. Curr Opin Genet Dev. 2015 Oct;34:10-6. doi: 10.1016/j.gde.2015.06.001. Epub 2015 Jul 12. Curr Opin Genet Dev. 2015. PMID: 26177475 Review.
A protocol for the identification and validation of novel genetic causes of kidney disease.
Mallett A, Patel C, Maier B, McGaughran J, Gabbett M, Takasato M, Cameron A, Trnka P, Alexander SI, Rangan G, Tchan MC, Caruana G, John G, Quinlan C, McCarthy HJ, Hyland V, Hoy WE, Wolvetang E, Taft R, Simons C, Healy H, Little M. Mallett A, et al. BMC Nephrol. 2015 Sep 15;16:152. doi: 10.1186/s12882-015-0148-8. BMC Nephrol. 2015. PMID: 26374634 Free PMC article.
227 results