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A de novo protein binding pair by computational design and directed evolution.
Karanicolas J, Corn JE, Chen I, Joachimiak LA, Dym O, Peck SH, Albeck S, Unger T, Hu W, Liu G, Delbecq S, Montelione GT, Spiegel CP, Liu DR, Baker D. Karanicolas J, et al. Among authors: liu g, liu dr. Mol Cell. 2011 Apr 22;42(2):250-60. doi: 10.1016/j.molcel.2011.03.010. Epub 2011 Mar 31. Mol Cell. 2011. PMID: 21458342 Free PMC article.
Principles for designing ideal protein structures.
Koga N, Tatsumi-Koga R, Liu G, Xiao R, Acton TB, Montelione GT, Baker D. Koga N, et al. Among authors: liu g. Nature. 2012 Nov 8;491(7423):222-7. doi: 10.1038/nature11600. Nature. 2012. PMID: 23135467 Free PMC article.
Control over overall shape and size in de novo designed proteins.
Lin YR, Koga N, Tatsumi-Koga R, Liu G, Clouser AF, Montelione GT, Baker D. Lin YR, et al. Among authors: liu g. Proc Natl Acad Sci U S A. 2015 Oct 6;112(40):E5478-85. doi: 10.1073/pnas.1509508112. Epub 2015 Sep 22. Proc Natl Acad Sci U S A. 2015. PMID: 26396255 Free PMC article.
Introduction of a polar core into the de novo designed protein Top7.
Basanta B, Chan KK, Barth P, King T, Sosnick TR, Hinshaw JR, Liu G, Everett JK, Xiao R, Montelione GT, Baker D. Basanta B, et al. Among authors: liu g. Protein Sci. 2016 Jul;25(7):1299-307. doi: 10.1002/pro.2899. Epub 2016 Mar 7. Protein Sci. 2016. PMID: 26873166 Free PMC article.
NMR structure determination for larger proteins using backbone-only data.
Raman S, Lange OF, Rossi P, Tyka M, Wang X, Aramini J, Liu G, Ramelot TA, Eletsky A, Szyperski T, Kennedy MA, Prestegard J, Montelione GT, Baker D. Raman S, et al. Among authors: liu g. Science. 2010 Feb 19;327(5968):1014-8. doi: 10.1126/science.1183649. Epub 2010 Feb 4. Science. 2010. PMID: 20133520 Free PMC article.
De novo protein design by citizen scientists.
Koepnick B, Flatten J, Husain T, Ford A, Silva DA, Bick MJ, Bauer A, Liu G, Ishida Y, Boykov A, Estep RD, Kleinfelter S, Nørgård-Solano T, Wei L, Players F, Montelione GT, DiMaio F, Popović Z, Khatib F, Cooper S, Baker D. Koepnick B, et al. Among authors: liu g. Nature. 2019 Jun;570(7761):390-394. doi: 10.1038/s41586-019-1274-4. Epub 2019 Jun 5. Nature. 2019. PMID: 31168091 Free PMC article.
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