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Therapeutic efficacy of an Fc-enhanced TCR-like antibody to the intracellular WT1 oncoprotein.
Veomett N, Dao T, Liu H, Xiang J, Pankov D, Dubrovsky L, Whitten JA, Park SM, Korontsvit T, Zakhaleva V, Casey E, Curcio M, Kharas MG, O'Reilly RJ, Liu C, Scheinberg DA. Veomett N, et al. Among authors: liu h, liu c. Clin Cancer Res. 2014 Aug 1;20(15):4036-46. doi: 10.1158/1078-0432.CCR-13-2756. Epub 2014 May 21. Clin Cancer Res. 2014. PMID: 24850840 Free PMC article.
Targeting the intracellular WT1 oncogene product with a therapeutic human antibody.
Dao T, Yan S, Veomett N, Pankov D, Zhou L, Korontsvit T, Scott A, Whitten J, Maslak P, Casey E, Tan T, Liu H, Zakhaleva V, Curcio M, Doubrovina E, O'Reilly RJ, Liu C, Scheinberg DA. Dao T, et al. Among authors: liu h, liu c. Sci Transl Med. 2013 Mar 13;5(176):176ra33. doi: 10.1126/scitranslmed.3005661. Sci Transl Med. 2013. PMID: 23486779 Free PMC article.
Targeting Alpha-Fetoprotein (AFP)-MHC Complex with CAR T-Cell Therapy for Liver Cancer.
Liu H, Xu Y, Xiang J, Long L, Green S, Yang Z, Zimdahl B, Lu J, Cheng N, Horan LH, Liu B, Yan S, Wang P, Diaz J, Jin L, Nakano Y, Morales JF, Zhang P, Liu LX, Staley BK, Priceman SJ, Brown CE, Forman SJ, Chan VW, Liu C. Liu H, et al. Among authors: liu c, liu b, liu lx. Clin Cancer Res. 2017 Jan 15;23(2):478-488. doi: 10.1158/1078-0432.CCR-16-1203. Epub 2016 Aug 17. Clin Cancer Res. 2017. PMID: 27535982
Generation of TCR-Like Antibodies Using Phage Display.
Santich BH, Liu H, Liu C, Cheung NK. Santich BH, et al. Among authors: liu h, liu c. Methods Mol Biol. 2015;1348:191-204. doi: 10.1007/978-1-4939-2999-3_17. Methods Mol Biol. 2015. PMID: 26424273
A novel antibody-TCR (AbTCR) platform combines Fab-based antigen recognition with gamma/delta-TCR signaling to facilitate T-cell cytotoxicity with low cytokine release.
Xu Y, Yang Z, Horan LH, Zhang P, Liu L, Zimdahl B, Green S, Lu J, Morales JF, Barrett DM, Grupp SA, Chan VW, Liu H, Liu C. Xu Y, et al. Among authors: liu h, liu l, liu c. Cell Discov. 2018 Nov 20;4:62. doi: 10.1038/s41421-018-0066-6. eCollection 2018. Cell Discov. 2018. PMID: 30479831 Free PMC article.
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