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Minireview: GNAS: normal and abnormal functions.
Weinstein LS, Liu J, Sakamoto A, Xie T, Chen M. Weinstein LS, et al. Endocrinology. 2004 Dec;145(12):5459-64. doi: 10.1210/en.2004-0865. Epub 2004 Aug 26. Endocrinology. 2004. PMID: 15331575 Review.
Severe obesity and insulin resistance due to deletion of the maternal Gsalpha allele is reversed by paternal deletion of the Gsalpha imprint control region.
Xie T, Chen M, Gavrilova O, Lai EW, Liu J, Weinstein LS. Xie T, et al. Endocrinology. 2008 May;149(5):2443-50. doi: 10.1210/en.2007-1458. Epub 2008 Jan 17. Endocrinology. 2008. PMID: 18202131 Free PMC article.
Alternative Gnas gene products have opposite effects on glucose and lipid metabolism.
Chen M, Gavrilova O, Liu J, Xie T, Deng C, Nguyen AT, Nackers LM, Lorenzo J, Shen L, Weinstein LS. Chen M, et al. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7386-91. doi: 10.1073/pnas.0408268102. Epub 2005 May 9. Proc Natl Acad Sci U S A. 2005. PMID: 15883378 Free PMC article.
Fibroblast growth factor-23 is regulated by 1alpha,25-dihydroxyvitamin D.
Collins MT, Lindsay JR, Jain A, Kelly MH, Cutler CM, Weinstein LS, Liu J, Fedarko NS, Winer KK. Collins MT, et al. J Bone Miner Res. 2005 Nov;20(11):1944-50. doi: 10.1359/JBMR.050718. Epub 2005 Jul 18. J Bone Miner Res. 2005. PMID: 16234967
Genetic diseases associated with heterotrimeric G proteins.
Weinstein LS, Chen M, Xie T, Liu J. Weinstein LS, et al. Trends Pharmacol Sci. 2006 May;27(5):260-6. doi: 10.1016/ Epub 2006 Apr 5. Trends Pharmacol Sci. 2006. PMID: 16600389 Review.
Identification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunit.
Liu J, Chen M, Deng C, Bourc'his D, Nealon JG, Erlichman B, Bestor TH, Weinstein LS. Liu J, et al. Proc Natl Acad Sci U S A. 2005 Apr 12;102(15):5513-8. doi: 10.1073/pnas.0408262102. Epub 2005 Apr 5. Proc Natl Acad Sci U S A. 2005. PMID: 15811946 Free PMC article.
The stimulatory G protein alpha-subunit Gs alpha is imprinted in human thyroid glands: implications for thyroid function in pseudohypoparathyroidism types 1A and 1B.
Liu J, Erlichman B, Weinstein LS. Liu J, et al. J Clin Endocrinol Metab. 2003 Sep;88(9):4336-41. doi: 10.1210/jc.2003-030393. J Clin Endocrinol Metab. 2003. PMID: 12970307 Clinical Trial.
Gs(alpha) mutations and imprinting defects in human disease.
Weinstein LS, Chen M, Liu J. Weinstein LS, et al. Ann N Y Acad Sci. 2002 Jun;968:173-97. doi: 10.1111/j.1749-6632.2002.tb04335.x. Ann N Y Acad Sci. 2002. PMID: 12119276 Review.
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