Molecular mechanisms involved in muscarinic acetylcholine receptor-mediated G protein activation studied by insertion mutagenesis.
Liu J, Blin N, Conklin BR, Wess J.
Liu J, et al.
J Biol Chem. 1996 Mar 15;271(11):6172-8. doi: 10.1074/jbc.271.11.6172.
J Biol Chem. 1996.
PMID: 8626406
Free article.
We have recently shown that a four-amino acid epitope (VTIL) on the m2 muscarinic receptor (corresponding to Val385, Thr386, Ile389, and Leu390) is essential for Gi/o coupling specificity and Gi/o activation (Liu, J., Conklin, B. R., Blin, N., Yun, J., and We …
We have recently shown that a four-amino acid epitope (VTIL) on the m2 muscarinic receptor (corresponding to Val385, Thr386, Ile389, and Leu …