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421 results
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P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways.
Huynh N, Liu KH, Baldwin GS, He H. Huynh N, et al. Among authors: liu kh. Biochim Biophys Acta. 2010 Sep;1803(9):1106-13. doi: 10.1016/j.bbamcr.2010.05.007. Epub 2010 Jun 1. Biochim Biophys Acta. 2010. PMID: 20595063
Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer.
Merino D, Whittle JR, Vaillant F, Serrano A, Gong JN, Giner G, Maragno AL, Chanrion M, Schneider E, Pal B, Li X, Dewson G, Gräsel J, Liu K, Lalaoui N, Segal D, Herold MJ, Huang DCS, Smyth GK, Geneste O, Lessene G, Visvader JE, Lindeman GJ. Merino D, et al. Sci Transl Med. 2017 Aug 2;9(401):eaam7049. doi: 10.1126/scitranslmed.aam7049. Sci Transl Med. 2017. PMID: 28768804
EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.
Fu NY, Rios AC, Pal B, Soetanto R, Lun AT, Liu K, Beck T, Best SA, Vaillant F, Bouillet P, Strasser A, Preiss T, Smyth GK, Lindeman GJ, Visvader JE. Fu NY, et al. Nat Cell Biol. 2015 Apr;17(4):365-75. doi: 10.1038/ncb3117. Epub 2015 Mar 2. Nat Cell Biol. 2015. PMID: 25730472
Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive.
Fu NY, Rios AC, Pal B, Law CW, Jamieson P, Liu R, Vaillant F, Jackling F, Liu KH, Smyth GK, Lindeman GJ, Ritchie ME, Visvader JE. Fu NY, et al. Among authors: liu r, liu kh. Nat Cell Biol. 2017 Mar;19(3):164-176. doi: 10.1038/ncb3471. Epub 2017 Feb 13. Nat Cell Biol. 2017. PMID: 28192422
Demonstration and biological significance of a gastrin-P21-activated kinase 1 feedback loop in colorectal cancer cells.
Huynh N, Liu KH, Yim M, Shulkes A, Baldwin GS, He H. Huynh N, et al. Among authors: liu kh. Physiol Rep. 2014 Jun 24;2(6):e12048. doi: 10.14814/phy2.12048. Print 2014 Jun 1. Physiol Rep. 2014. PMID: 24963032 Free PMC article.
P21-activated kinase 1 promotes colorectal cancer survival by up-regulation of hypoxia-inducible factor-1α.
Liu KH, Huynh N, Patel O, Shulkes A, Baldwin G, He H. Liu KH, et al. Cancer Lett. 2013 Oct 28;340(1):22-9. doi: 10.1016/j.canlet.2013.06.024. Epub 2013 Jun 26. Cancer Lett. 2013. PMID: 23811286
P-21 activated kinase 1 knockdown inhibits β-catenin signalling and blocks colorectal cancer growth.
He H, Huynh N, Liu KH, Malcontenti-Wilson C, Zhu J, Christophi C, Shulkes A, Baldwin GS. He H, et al. Among authors: liu kh. Cancer Lett. 2012 Apr 1;317(1):65-71. doi: 10.1016/j.canlet.2011.11.014. Epub 2011 Nov 15. Cancer Lett. 2012. PMID: 22100495
Involvement of G proteins of the Rho family in the regulation of Bcl-2-like protein expression and caspase 3 activation by Gastrins.
He H, Yim M, Liu KH, Cody SC, Shulkes A, Baldwin GS. He H, et al. Among authors: liu kh. Cell Signal. 2008 Jan;20(1):83-93. doi: 10.1016/j.cellsig.2007.08.018. Epub 2007 Sep 11. Cell Signal. 2008. PMID: 17936584
A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.
Sheridan JM, Ritchie ME, Best SA, Jiang K, Beck TJ, Vaillant F, Liu K, Dickins RA, Smyth GK, Lindeman GJ, Visvader JE. Sheridan JM, et al. BMC Cancer. 2015 Apr 3;15:221. doi: 10.1186/s12885-015-1187-z. BMC Cancer. 2015. PMID: 25879659 Free PMC article.
Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling.
Pal B, Chen Y, Vaillant F, Jamieson P, Gordon L, Rios AC, Wilcox S, Fu N, Liu KH, Jackling FC, Davis MJ, Lindeman GJ, Smyth GK, Visvader JE. Pal B, et al. Among authors: liu kh. Nat Commun. 2017 Nov 20;8(1):1627. doi: 10.1038/s41467-017-01560-x. Nat Commun. 2017. PMID: 29158510 Free PMC article.
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