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A chemical-inducible CRISPR-Cas9 system for rapid control of genome editing.
Liu KI, Ramli MN, Woo CW, Wang Y, Zhao T, Zhang X, Yim GR, Chong BY, Gowher A, Chua MZ, Jung J, Lee JH, Tan MH. Liu KI, et al. Nat Chem Biol. 2016 Nov;12(11):980-987. doi: 10.1038/nchembio.2179. Epub 2016 Sep 12. Nat Chem Biol. 2016. PMID: 27618190
Dynamic landscape and regulation of RNA editing in mammals.
Tan MH, Li Q, Shanmugam R, Piskol R, Kohler J, Young AN, Liu KI, Zhang R, Ramaswami G, Ariyoshi K, Gupte A, Keegan LP, George CX, Ramu A, Huang N, Pollina EA, Leeman DS, Rustighi A, Goh YPS; GTEx Consortium; Laboratory, Data Analysis &Coordinating Center (LDACC)—Analysis Working Group; Statistical Methods groups—Analysis Working Group; Enhancing GTEx (eGTEx) groups; NIH Common Fund; NIH/NCI; NIH/NHGRI; NIH/NIMH; NIH/NIDA; Biospecimen Collection Source Site—NDRI; Biospecimen Collection Source Site—RPCI; Biospecimen Core Resource—VARI; Brain Bank Repository—University of Miami Brain Endowment Bank; Leidos Biomedical—Project Management; ELSI Study; Genome Browser Data Integration &Visualization—EBI; Genome Browser Data Integration &Visualization—UCSC Genomics Institute, University of California Santa Cruz, Chawla A, Del Sal G, Peltz G, Brunet A, Conrad DF, Samuel CE, O'Connell MA, Walkley CR, Nishikura K, Li JB. Tan MH, et al. Among authors: Liu KI. Nature. 2017 Oct 11;550(7675):249-254. doi: 10.1038/nature24041. Nature. 2017. PMID: 29022589 Free PMC article.
Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells.
Wang Y, Liu KI, Sutrisnoh NB, Srinivasan H, Zhang J, Li J, Zhang F, Lalith CRJ, Xing H, Shanmugam R, Foo JN, Yeo HT, Ooi KH, Bleckwehl T, Par YYR, Lee SM, Ismail NNB, Sanwari NAB, Lee STV, Lew J, Tan MH. Wang Y, et al. Among authors: Liu KI. Genome Biol. 2018 May 29;19(1):62. doi: 10.1186/s13059-018-1445-x. Genome Biol. 2018. PMID: 29843790 Free PMC article.
SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates.
Shanmugam R, Zhang F, Srinivasan H, Charles Richard JL, Liu KI, Zhang X, Woo CWA, Chua ZHM, Buschdorf JP, Meaney MJ, Tan MH. Shanmugam R, et al. Among authors: Liu KI. Nucleic Acids Res. 2018 Aug 21;46(14):7379-7395. doi: 10.1093/nar/gky615. Nucleic Acids Res. 2018. PMID: 29992293 Free PMC article.
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