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SU086, an inhibitor of HSP90, impairs glycolysis and represents a treatment strategy for advanced prostate cancer.
Rice MA, Kumar V, Tailor D, Garcia-Marques FJ, Hsu EC, Liu S, Bermudez A, Kanchustambham V, Shankar V, Inde Z, Alabi BR, Muruganantham A, Shen M, Pandrala M, Nolley R, Aslan M, Ghoochani A, Agarwal A, Buckup M, Kumar M, Going CC, Peehl DM, Dixon SJ, Zare RN, Brooks JD, Pitteri SJ, Malhotra SV, Stoyanova T. Rice MA, et al. Among authors: liu s. Cell Rep Med. 2022 Feb 2;3(2):100502. doi: 10.1016/j.xcrm.2021.100502. eCollection 2022 Feb 15. Cell Rep Med. 2022. PMID: 35243415 Free PMC article.
Trop2 is a driver of metastatic prostate cancer with neuroendocrine phenotype via PARP1.
Hsu EC, Rice MA, Bermudez A, Marques FJG, Aslan M, Liu S, Ghoochani A, Zhang CA, Chen YS, Zlitni A, Kumar S, Nolley R, Habte F, Shen M, Koul K, Peehl DM, Zoubeidi A, Gambhir SS, Kunder CA, Pitteri SJ, Brooks JD, Stoyanova T. Hsu EC, et al. Among authors: liu s. Proc Natl Acad Sci U S A. 2020 Jan 28;117(4):2032-2042. doi: 10.1073/pnas.1905384117. Epub 2020 Jan 13. Proc Natl Acad Sci U S A. 2020. PMID: 31932422 Free PMC article.
Plectin is a regulator of prostate cancer growth and metastasis.
Buckup M, Rice MA, Hsu EC, Garcia-Marques F, Liu S, Aslan M, Bermudez A, Huang J, Pitteri SJ, Stoyanova T. Buckup M, et al. Among authors: liu s. Oncogene. 2021 Jan;40(3):663-676. doi: 10.1038/s41388-020-01557-9. Epub 2020 Nov 20. Oncogene. 2021. PMID: 33219316 Free PMC article.
Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer.
Liu S, Shen M, Hsu EC, Zhang CA, Garcia-Marques F, Nolley R, Koul K, Rice MA, Aslan M, Pitteri SJ, Massie C, George A, Brooks JD, Gnanapragasam VJ, Stoyanova T. Liu S, et al. Br J Cancer. 2021 Mar;124(5):896-900. doi: 10.1038/s41416-020-01200-0. Epub 2020 Dec 8. Br J Cancer. 2021. PMID: 33288843 Free PMC article.
Oncogene-mediated metabolic gene signature predicts breast cancer outcome.
Aslan M, Hsu EC, Garcia-Marques FJ, Bermudez A, Liu S, Shen M, West M, Zhang CA, Rice MA, Brooks JD, West R, Pitteri SJ, Győrffy B, Stoyanova T. Aslan M, et al. Among authors: liu s. NPJ Breast Cancer. 2021 Oct 28;7(1):141. doi: 10.1038/s41523-021-00341-6. NPJ Breast Cancer. 2021. PMID: 34711841 Free PMC article.
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