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The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors.
Liu SK, Fang N, Koretzky GA, McGlade CJ. Liu SK, et al. Curr Biol. 1999 Jan 28;9(2):67-75. doi: 10.1016/s0960-9822(99)80017-7. Curr Biol. 1999. PMID: 10021361
A high-affinity Arg-X-X-Lys SH3 binding motif confers specificity for the interaction between Gads and SLP-76 in T cell signaling.
Berry DM, Nash P, Liu SK, Pawson T, McGlade CJ. Berry DM, et al. Among authors: liu sk. Curr Biol. 2002 Aug 6;12(15):1336-41. doi: 10.1016/s0960-9822(02)01038-2. Curr Biol. 2002. PMID: 12176364
Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells.
Schmandt R, Liu SK, McGlade CJ. Schmandt R, et al. Among authors: liu sk. Oncogene. 1999 Mar 11;18(10):1867-79. doi: 10.1038/sj.onc.1202507. Oncogene. 1999. PMID: 10086341
Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc.
Liu SK, McGlade CJ. Liu SK, et al. Oncogene. 1998 Dec 17;17(24):3073-82. doi: 10.1038/sj.onc.1202337. Oncogene. 1998. PMID: 9872323
Requirement for the SLP-76 adaptor GADS in T cell development.
Yoder J, Pham C, Iizuka YM, Kanagawa O, Liu SK, McGlade J, Cheng AM. Yoder J, et al. Among authors: liu sk. Science. 2001 Mar 9;291(5510):1987-91. doi: 10.1126/science.1057176. Science. 2001. PMID: 11239162
Association of Grb2, Gads, and phospholipase C-gamma 1 with phosphorylated LAT tyrosine residues. Effect of LAT tyrosine mutations on T cell angigen receptor-mediated signaling.
Zhang W, Trible RP, Zhu M, Liu SK, McGlade CJ, Samelson LE. Zhang W, et al. Among authors: liu sk. J Biol Chem. 2000 Jul 28;275(30):23355-61. doi: 10.1074/jbc.M000404200. J Biol Chem. 2000. PMID: 10811803
The adaptor protein Gads (Grb2-related adaptor downstream of Shc) is implicated in coupling hemopoietic progenitor kinase-1 to the activated TCR.
Liu SK, Smith CA, Arnold R, Kiefer F, McGlade CJ. Liu SK, et al. J Immunol. 2000 Aug 1;165(3):1417-26. doi: 10.4049/jimmunol.165.3.1417. J Immunol. 2000. PMID: 10903746
The role of Gads in hematopoietic cell signalling.
Liu SK, Berry DM, McGlade CJ. Liu SK, et al. Oncogene. 2001 Oct 1;20(44):6284-90. doi: 10.1038/sj.onc.1204771. Oncogene. 2001. PMID: 11607830 Review.
Interaction of linker for activation of T cells with multiple adapter proteins in platelets activated by the glycoprotein VI-selective ligand, convulxin.
Asazuma N, Wilde JI, Berlanga O, Leduc M, Leo A, Schweighoffer E, Tybulewicz V, Bon C, Liu SK, McGlade CJ, Schraven B, Watson SP. Asazuma N, et al. Among authors: liu sk. J Biol Chem. 2000 Oct 27;275(43):33427-34. doi: 10.1074/jbc.M001439200. J Biol Chem. 2000. PMID: 10942756
Characterization of miR-200 family members as blood biomarkers for human and laying hen ovarian cancer.
Choi PW, Bahrampour A, Ng SK, Liu SK, Qiu W, Xie F, Kuo WP, Kwong J, Hales KH, Hales DB, Wong KK, Norwitz ER, Chow CK, Berkowitz RS, Ng SW. Choi PW, et al. Among authors: liu sk. Sci Rep. 2020 Nov 18;10(1):20071. doi: 10.1038/s41598-020-77068-0. Sci Rep. 2020. PMID: 33208870 Free PMC article.
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