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A candidate vaccine against influenza virus intensively improved the immunogenicity of a neutralizing epitope.
Lu Y, Ding J, Liu W, Chen YH. Lu Y, et al. Among authors: liu w. Int Arch Allergy Immunol. 2002 Mar;127(3):245-50. doi: 10.1159/000053869. Int Arch Allergy Immunol. 2002. PMID: 11979050
N-terminus of M2 protein could induce antibodies with inhibitory activity against influenza virus replication.
Liu W, Li H, Chen YH. Liu W, et al. FEMS Immunol Med Microbiol. 2003 Mar 20;35(2):141-6. doi: 10.1016/S0928-8244(03)00009-9. FEMS Immunol Med Microbiol. 2003. PMID: 12628550
Monoclonal antibodies recognizing EVETPIRN epitope of influenza A virus M2 protein could protect mice from lethal influenza A virus challenge.
Liu W, Zou P, Chen YH. Liu W, et al. Immunol Lett. 2004 May 15;93(2-3):131-6. doi: 10.1016/j.imlet.2004.03.003. Immunol Lett. 2004. PMID: 15158608
High epitope density in a single recombinant protein molecule of the extracellular domain of influenza A virus M2 protein significantly enhances protective immunity.
Liu W, Peng Z, Liu Z, Lu Y, Ding J, Chen YH. Liu W, et al. Among authors: liu z. Vaccine. 2004 Dec 2;23(3):366-71. doi: 10.1016/j.vaccine.2004.05.028. Vaccine. 2004. PMID: 15530682
The epitope recognized by a monoclonal antibody in influenza A virus M2 protein is immunogenic and confers immune protection.
Zou P, Liu W, Chen YH. Zou P, et al. Among authors: liu w. Int Immunopharmacol. 2005 Apr;5(4):631-5. doi: 10.1016/j.intimp.2004.12.005. Int Immunopharmacol. 2005. PMID: 15710332
Sequence comparison between the extracellular domain of M2 protein human and avian influenza A virus provides new information for bivalent influenza vaccine design.
Liu W, Zou P, Ding J, Lu Y, Chen YH. Liu W, et al. Microbes Infect. 2005 Feb;7(2):171-7. doi: 10.1016/j.micinf.2004.10.006. Epub 2004 Dec 25. Microbes Infect. 2005. PMID: 15777646
Fine-epitope mapping of an antibody that binds the ectodomain of influenza matrix protein 2.
Zou P, Liu W, Wu F, Chen YH. Zou P, et al. Among authors: liu w. FEMS Immunol Med Microbiol. 2008 Jun;53(1):79-84. doi: 10.1111/j.1574-695X.2008.00402.x. Epub 2008 Apr 9. FEMS Immunol Med Microbiol. 2008. PMID: 18400009
Discrimination of membrane antigen affinity by B cells requires dominance of kinetic proofreading over serial engagement.
Tsourkas PK, Liu W, Das SC, Pierce SK, Raychaudhuri S. Tsourkas PK, et al. Among authors: liu w. Cell Mol Immunol. 2012 Jan;9(1):62-74. doi: 10.1038/cmi.2011.29. Epub 2011 Sep 12. Cell Mol Immunol. 2012. PMID: 21909127 Free PMC article.
The growth of B cell receptor microcluster is a universal response of B cells encountering antigens with different motion features.
Wan Z, Liu W. Wan Z, et al. Among authors: liu w. Protein Cell. 2012 Jul;3(7):545-58. doi: 10.1007/s13238-012-2054-1. Epub 2012 Jul 10. Protein Cell. 2012. PMID: 22773344 Free PMC article.
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