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Antiemetic Effects of Cannabinoid Agonists in Nonhuman Primates.
Wooldridge LM, Ji L, Liu Y, Nikas SP, Makriyannis A, Bergman J, Kangas BD. Wooldridge LM, et al. Among authors: liu y. J Pharmacol Exp Ther. 2020 Sep;374(3):462-468. doi: 10.1124/jpet.120.265710. Epub 2020 Jun 19. J Pharmacol Exp Ther. 2020. PMID: 32561684 Free PMC article.
( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.
Liu Y, Ji L, Eno M, Kudalkar S, Li AL, Schimpgen M, Benchama O, Morales P, Xu S, Hurst D, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis DP, Zhou H, Honrao C, Mackie K, Reggio P, Hohmann AG, Marnett LJ, Makriyannis A, Nikas SP. Liu Y, et al. J Med Chem. 2018 Oct 11;61(19):8639-8657. doi: 10.1021/acs.jmedchem.8b00611. Epub 2018 Sep 21. J Med Chem. 2018. PMID: 30196704
Synthesis of Functionalized Cannabilactones.
Liu Y, Ho TC, Baradwan M, Pascual Lopez-Alberca M, Iliopoulos-Tsoutsouvas C, Nikas SP, Makriyannis A. Liu Y, et al. Molecules. 2020 Feb 6;25(3):684. doi: 10.3390/molecules25030684. Molecules. 2020. PMID: 32041131 Free PMC article.
Cannabinoid-2 Agonism with AM2301 Mitigates Morphine-Induced Respiratory Depression.
Wiese BM, Liktor-Busa E, Levine A, Couture SA, Nikas SP, Ji L, Liu Y, Mackie K, Makriyannis A, Largent-Milnes TM, Vanderah TW. Wiese BM, et al. Among authors: liu y. Cannabis Cannabinoid Res. 2021 Oct;6(5):401-412. doi: 10.1089/can.2020.0076. Epub 2020 Nov 13. Cannabis Cannabinoid Res. 2021. PMID: 33998869 Free PMC article.
Brain Penetrant, but not Peripherally Restricted, Synthetic Cannabinoid 1 Receptor Agonists Promote Morphine-Mediated Respiratory Depression.
Wiese BM, Liktor-Busa E, Couture SA, Nikas SP, Ji L, Liu Y, Makriyannis A, Spigelman I, Vanderah TW, Largent-Milnes TM. Wiese BM, et al. Among authors: liu y. Cannabis Cannabinoid Res. 2022 Oct;7(5):621-627. doi: 10.1089/can.2021.0090. Epub 2021 Dec 17. Cannabis Cannabinoid Res. 2022. PMID: 34935460 Free PMC article.
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