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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1963 1
1964 2
1965 1
1969 1
1973 2
1974 1
1977 1
1978 1
1980 1
1981 1
1982 2
1983 1
1984 2
1986 1
1987 2
1988 3
1989 4
1990 4
1991 5
1992 5
1993 2
1994 13
1995 2
1996 6
1997 2
1998 2
1999 8
2000 4
2001 3
2002 3
2003 5
2004 6
2005 8
2006 12
2007 9
2008 15
2009 16
2010 28
2011 25
2012 38
2013 35
2014 49
2015 48
2016 73
2017 69
2018 33
2019 29
2020 42
2021 35
2022 27
2023 27
2024 37
2025 15

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690 results

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Page 1
Cholangiocarcinoma.
Brindley PJ, Bachini M, Ilyas SI, Khan SA, Loukas A, Sirica AE, Teh BT, Wongkham S, Gores GJ. Brindley PJ, et al. Nat Rev Dis Primers. 2021 Sep 9;7(1):65. doi: 10.1038/s41572-021-00300-2. Nat Rev Dis Primers. 2021. PMID: 34504109 Free PMC article. Review.
Each anatomic subtype has distinct genetic aberrations, clinical presentations and therapeutic approaches. In endemic regions, liver fluke infection is associated with CCA, owing to the oncogenic effect of the associated chronic biliary tract inflammation. ...CCA is …
Each anatomic subtype has distinct genetic aberrations, clinical presentations and therapeutic approaches. In endemic regions, liver …
The Role of Cancer-Associated Fibroblasts and Fibrosis in Liver Cancer.
Affo S, Yu LX, Schwabe RF. Affo S, et al. Annu Rev Pathol. 2017 Jan 24;12:153-186. doi: 10.1146/annurev-pathol-052016-100322. Epub 2016 Dec 5. Annu Rev Pathol. 2017. PMID: 27959632 Free PMC article. Review.
Liver cancer is the second leading cause of cancer mortality worldwide, causing more than 700,000 deaths annually. Because of the wide landscape of genomic alterations and limited therapeutic success of targeting tumor cells, a recent focus has been on better …
Liver cancer is the second leading cause of cancer mortality worldwide, causing more than 700,000 deaths annually. Beca …
Updated epidemiology of gastrointestinal cancers in East Asia.
Huang J, Lucero-Prisno DE 3rd, Zhang L, Xu W, Wong SH, Ng SC, Wong MCS. Huang J, et al. Nat Rev Gastroenterol Hepatol. 2023 May;20(5):271-287. doi: 10.1038/s41575-022-00726-3. Epub 2023 Jan 11. Nat Rev Gastroenterol Hepatol. 2023. PMID: 36631716 Review.
Although there has been much progress in screening colorectal cancer, the prognosis of other gastrointestinal cancers tends to be poor. The highest burden of gastrointestinal cancers, including stomach, liver, oesophageal and gallbladder cancers …
Although there has been much progress in screening colorectal cancer, the prognosis of other gastrointestinal cancers tends to …
Liver Fluke-Associated Biliary Tract Cancer.
Prueksapanich P, Piyachaturawat P, Aumpansub P, Ridtitid W, Chaiteerakij R, Rerknimitr R. Prueksapanich P, et al. Gut Liver. 2018 May 15;12(3):236-245. doi: 10.5009/gnl17102. Gut Liver. 2018. PMID: 28783896 Free PMC article. Review.
A diagnosis of liver fluke infection often relies on stool samples, including microscopic examination, polymerase chain reaction-based assays, and fluke antigen detection. ...The "liver fluke-cholangiocarcinoma" carcinogenesis pathways consist o …
A diagnosis of liver fluke infection often relies on stool samples, including microscopic examination, polymerase chain reacti …
Parasite-associated morbidity: liver fluke infection and bile duct cancer in northeast Thailand.
Sithithaworn P, Haswell-Elkins MR, Mairiang P, Satarug S, Mairiang E, Vatanasapt V, Elkins DB. Sithithaworn P, et al. Int J Parasitol. 1994 Sep;24(6):833-43. doi: 10.1016/0020-7519(94)90009-4. Int J Parasitol. 1994. PMID: 7982745 Review.
The most severe consequence of liver fluke infection is cholangiocarcinoma, i.e. cancer of the bile duct epithelium. ...Finally, the paper will close with a brief commentary on the prospects for control of the parasite and its likely impact on the frequency o …
The most severe consequence of liver fluke infection is cholangiocarcinoma, i.e. cancer of the bile duct epithelium. .. …
Editorial: Parasites and Cancer.
Botelho MC, Richter J. Botelho MC, et al. Front Med (Lausanne). 2019 Mar 22;6:55. doi: 10.3389/fmed.2019.00055. eCollection 2019. Front Med (Lausanne). 2019. PMID: 30968025 Free PMC article. No abstract available.
Mechanistic insights into liver-fluke-induced bile-duct cancer.
Smout MJ, Laha T, Chaiyadet S, Brindley PJ, Loukas A. Smout MJ, et al. Trends Parasitol. 2024 Dec;40(12):1183-1196. doi: 10.1016/j.pt.2024.10.012. Epub 2024 Nov 8. Trends Parasitol. 2024. PMID: 39521672 Free PMC article. Review.
Liver fluke infection is a major risk for cholangiocarcinoma (CCA). It has been established that the Asian liver flukes, Clonorchis sinensis and Opisthorchis viverrini secrete growth factors, digestive enzymes, and extracellular vesicles (EVs) which contribut …
Liver fluke infection is a major risk for cholangiocarcinoma (CCA). It has been established that the Asian liver flukes …
Associations of Liver Fluke Infection and Cholangiocarcinoma: A Scoping Review.
Sivanand A, Talati D, Kalariya Y, Patel P, Gandhi SK. Sivanand A, et al. Cureus. 2023 Oct 3;15(10):e46400. doi: 10.7759/cureus.46400. eCollection 2023 Oct. Cureus. 2023. PMID: 37927641 Free PMC article.
Multistep processes underlie carcinogenesis induced by chronic infection with the fish-borne liver fluke. Mechanical injury from fluke feeding and migrating in the bile duct causes damage to the bile duct epithelial cells. ...Improvements in hygiene, health e …
Multistep processes underlie carcinogenesis induced by chronic infection with the fish-borne liver fluke. Mechanical injury fr …
Liver fluke-associated cholangiocarcinoma.
Watanapa P, Watanapa WB. Watanapa P, et al. Br J Surg. 2002 Aug;89(8):962-70. doi: 10.1046/j.1365-2168.2002.02143.x. Br J Surg. 2002. PMID: 12153620 Review.
Early detection of bile duct malignancy is difficult and not clinically available at present, although cholangiocarcinoma-associated soluble antigen has been reported in an experimental study to be a useful early marker of cancer development. Long-term survival after surgi …
Early detection of bile duct malignancy is difficult and not clinically available at present, although cholangiocarcinoma-associated soluble …
Liver Flukes: Clonorchis and Opisthorchis.
Saijuntha W, Sithithaworn P, Wangboon C, Andrews RH, Petney TN. Saijuntha W, et al. Adv Exp Med Biol. 2024;1454:239-284. doi: 10.1007/978-3-031-60121-7_7. Adv Exp Med Biol. 2024. PMID: 39008268 Review.
To reduce hepatobiliary morbidity and CCA, the primary intervention measures focus on control and elimination of the liver fluke. Accurate diagnosis of liver fluke infections in both human and other mammalian, snail and fish intermediate hosts is impor …
To reduce hepatobiliary morbidity and CCA, the primary intervention measures focus on control and elimination of the liver fluke …
690 results