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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1972 1
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1975 1
1976 5
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1978 2
1979 4
1980 2
1981 2
1983 2
1986 3
1987 1
1988 5
1989 3
1990 6
1991 7
1993 4
1994 2
1995 4
1996 1
1997 1
1998 2
2000 1
2001 1
2005 3
2008 2
2009 3
2010 4
2011 10
2012 4
2013 4
2014 2
2015 4
2016 6
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2026 32

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432 results

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Page 1
Metabolism and liver toxicity of cannabidiol.
Chen S, Li Y, Li X, Wu Q, Puig M, Moulin F, Gingrich J, Guo L. Chen S, et al. J Environ Sci Health C Toxicol Carcinog. 2024;42(3):238-254. doi: 10.1080/26896583.2024.2366741. Epub 2024 Jun 21. J Environ Sci Health C Toxicol Carcinog. 2024. PMID: 38904421 Free PMC article. Review.
Adverse effects related to exposure of humans to CBD include changes in appetite, gastrointestinal discomfort, fatigue, and elevated liver aminotransferase enzymes. Animal studies reported changes in organ weight, reproduction, liver function, and the immune system. …
Adverse effects related to exposure of humans to CBD include changes in appetite, gastrointestinal discomfort, fatigue, and elevated live …
The Role of Cannabidiol in Liver Disease: A Systemic Review.
Chen S, Kim JK. Chen S, et al. Int J Mol Sci. 2024 Feb 17;25(4):2370. doi: 10.3390/ijms25042370. Int J Mol Sci. 2024. PMID: 38397045 Free PMC article.
Cannabidiol (CBD), a non-psychoactive phytocannabinoid abundant in Cannabis sativa, has gained considerable attention for its anti-inflammatory, antioxidant, analgesic, and neuroprotective properties. ...Metabolic dysfunction-associated steatotic liver disease (MASL …
Cannabidiol (CBD), a non-psychoactive phytocannabinoid abundant in Cannabis sativa, has gained considerable attention for its anti-in …
Cannabidiol and Liver Enzyme Level Elevations in Healthy Adults: A Randomized Clinical Trial.
Florian J, Salcedo P, Burkhart K, Shah A, Chekka LMS, Keshishi D, Patel V, Yang S, Fein M, DePalma R, Matta M, Strauss DG, Rouse R. Florian J, et al. JAMA Intern Med. 2025 Sep 1;185(9):1070-1078. doi: 10.1001/jamainternmed.2025.2366. JAMA Intern Med. 2025. PMID: 40622698 Free PMC article. Clinical Trial.
IMPORTANCE: The wide use of unregulated cannabidiol (CBD) products among consumers raises safety concerns. Most research on CBD has studied the relatively high doses used by patients taking prescription CBD. ...OBJECTIVE: To study the effects of 4-weeks of twice-daily CBD …
IMPORTANCE: The wide use of unregulated cannabidiol (CBD) products among consumers raises safety concerns. Most research on CBD has s …
Trial of Cannabidiol for Drug-Resistant Seizures in the Dravet Syndrome.
Devinsky O, Cross JH, Laux L, Marsh E, Miller I, Nabbout R, Scheffer IE, Thiele EA, Wright S; Cannabidiol in Dravet Syndrome Study Group. Devinsky O, et al. N Engl J Med. 2017 May 25;376(21):2011-2020. doi: 10.1056/NEJMoa1611618. N Engl J Med. 2017. PMID: 28538134 Free article. Clinical Trial.
The frequency of total seizures of all types was significantly reduced with cannabidiol (P=0.03), but there was no significant reduction in nonconvulsive seizures. The percentage of patients who became seizure-free was 5% with cannabidiol and 0% with placebo (P=0.08 …
The frequency of total seizures of all types was significantly reduced with cannabidiol (P=0.03), but there was no significant reduct …
Cannabidiol.
[No authors listed] [No authors listed] 2023 Feb 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2023 Feb 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31644197 Free Books & Documents. Review.
High daily doses of cannabidiol are associated with frequent serum enzyme elevations during therapy, but has not been linked to cases of clinically apparent liver injury with jaundice. The lower doses of cannabidiol found typically in over-the-counter CBD pro …
High daily doses of cannabidiol are associated with frequent serum enzyme elevations during therapy, but has not been linked to cases …
Cannabidiol markedly alleviates skin and liver fibrosis.
Del Río C, Ruiz-Pino F, Prados ME, Fiebich BL, Tena-Sempere M, Muñoz E. Del Río C, et al. Front Pharmacol. 2022 Oct 19;13:981817. doi: 10.3389/fphar.2022.981817. eCollection 2022. Front Pharmacol. 2022. PMID: 36339540 Free PMC article.
Cannabidiol was demonstrated to reduce alcohol-induced liver inflammation and steatosis but its specific activity on the fibrotic process was not investigated. ...In a second model, non-alcoholic liver fibrosis was induced in mice by CCl(4) exposure. Canna …
Cannabidiol was demonstrated to reduce alcohol-induced liver inflammation and steatosis but its specific activity on the fibro …
Cannabidiol Adverse Effects and Toxicity.
Huestis MA, Solimini R, Pichini S, Pacifici R, Carlier J, Busardò FP. Huestis MA, et al. Curr Neuropharmacol. 2019;17(10):974-989. doi: 10.2174/1570159X17666190603171901. Curr Neuropharmacol. 2019. PMID: 31161980 Free PMC article. Review.
BACKGROUND: Currently, there is a great interest in the potential medical use of cannabidiol (CBD), a non-intoxicating cannabinoid. Productive pharmacological research on CBD occurred in the 1970s and intensified recently with many discoveries about the endocannabinoid sys …
BACKGROUND: Currently, there is a great interest in the potential medical use of cannabidiol (CBD), a non-intoxicating cannabinoid. P …
Effect of Cannabidiol on Drop Seizures in the Lennox-Gastaut Syndrome.
Devinsky O, Patel AD, Cross JH, Villanueva V, Wirrell EC, Privitera M, Greenwood SM, Roberts C, Checketts D, VanLandingham KE, Zuberi SM; GWPCARE3 Study Group. Devinsky O, et al. N Engl J Med. 2018 May 17;378(20):1888-1897. doi: 10.1056/NEJMoa1714631. N Engl J Med. 2018. PMID: 29768152 Free article. Clinical Trial.
Fourteen patients who received cannabidiol (9%) had elevated liver aminotransferase concentrations. CONCLUSIONS: Among children and adults with the Lennox-Gastaut syndrome, the addition of cannabidiol at a dose of 10 mg or 20 mg per kilogram per day to a conv …
Fourteen patients who received cannabidiol (9%) had elevated liver aminotransferase concentrations. CONCLUSIONS: Among childre …
Cannabidiol (CBD) as a potential therapeutic agent for liver cancer: a comprehensive review of current evidence.
Esmaeli M, Dehghanpour Dehabadi M. Esmaeli M, et al. Cancer Cell Int. 2025 Jun 18;25(1):215. doi: 10.1186/s12935-025-03870-3. Cancer Cell Int. 2025. PMID: 40533744 Free PMC article. Review.
Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality with limited treatment options. Cannabidiol (CBD), a non-psychoactive compound from Cannabis sativa, has shown anticancer properties. ...
Hepatocellular carcinoma (HCC) is a major cause of cancer-related mortality with limited treatment options. Cannabidiol (CBD), a non- …
Cannabidiol in canine epilepsy.
Potschka H, Bhatti SFM, Tipold A, McGrath S. Potschka H, et al. Vet J. 2022 Dec;290:105913. doi: 10.1016/j.tvjl.2022.105913. Epub 2022 Oct 6. Vet J. 2022. PMID: 36209995 Free article.
The anticonvulsant effect of cannabidiol (CBD), which has been confirmed by findings from animal models and human trials, has attracted the interest of veterinary practitioners and dog owners. ...Pharmacokinetic studies in dogs have demonstrated a low oral bioavailability …
The anticonvulsant effect of cannabidiol (CBD), which has been confirmed by findings from animal models and human trials, has attract …
432 results