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Mechanisms of resistance to the carbapenems.
Livingstone D, Gill MJ, Wise R. Livingstone D, et al. J Antimicrob Chemother. 1995 Jan;35(1):1-5. doi: 10.1093/jac/35.1.1. J Antimicrob Chemother. 1995. PMID: 7768757 No abstract available.
5α-Reductase type 1 deficiency or inhibition predisposes to insulin resistance, hepatic steatosis, and liver fibrosis in rodents.
Livingstone DE, Barat P, Di Rollo EM, Rees GA, Weldin BA, Rog-Zielinska EA, MacFarlane DP, Walker BR, Andrew R. Livingstone DE, et al. Diabetes. 2015 Feb;64(2):447-58. doi: 10.2337/db14-0249. Epub 2014 Sep 19. Diabetes. 2015. PMID: 25239636
Aromatase Inhibition Reduces Insulin Sensitivity in Healthy Men.
Gibb FW, Homer NZ, Faqehi AM, Upreti R, Livingstone DE, McInnes KJ, Andrew R, Walker BR. Gibb FW, et al. J Clin Endocrinol Metab. 2016 May;101(5):2040-6. doi: 10.1210/jc.2015-4146. Epub 2016 Mar 11. J Clin Endocrinol Metab. 2016. PMID: 26967690 Free PMC article. Clinical Trial.
Metformin Increases Cortisol Regeneration by 11βHSD1 in Obese Men With and Without Type 2 Diabetes Mellitus.
Anderson AJ, Andrew R, Homer NZ, Jones GC, Smith K, Livingstone DE, Walker BR, Stimson RH. Anderson AJ, et al. J Clin Endocrinol Metab. 2016 Oct;101(10):3787-3793. doi: 10.1210/jc.2016-2069. Epub 2016 Jul 26. J Clin Endocrinol Metab. 2016. PMID: 27459533 Free PMC article. Clinical Trial.
ABCC1 confers tissue-specific sensitivity to cortisol versus corticosterone: A rationale for safer glucocorticoid replacement therapy.
Nixon M, Mackenzie SD, Taylor AI, Homer NZ, Livingstone DE, Mouras R, Morgan RA, Mole DJ, Stimson RH, Reynolds RM, Elfick AP, Andrew R, Walker BR. Nixon M, et al. Sci Transl Med. 2016 Aug 17;8(352):352ra109. doi: 10.1126/scitranslmed.aaf9074. Sci Transl Med. 2016. PMID: 27535620
Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization.
Nixon M, Wake DJ, Livingstone DE, Stimson RH, Esteves CL, Seckl JR, Chapman KE, Andrew R, Walker BR. Nixon M, et al. Diabetes. 2012 Apr;61(4):790-6. doi: 10.2337/db11-0931. Epub 2012 Feb 22. Diabetes. 2012. PMID: 22357964 Free PMC article. Clinical Trial.
Bile acids modulate glucocorticoid metabolism and the hypothalamic-pituitary-adrenal axis in obstructive jaundice.
McNeilly AD, Macfarlane DP, O'Flaherty E, Livingstone DE, Mitić T, McConnell KM, McKenzie SM, Davies E, Reynolds RM, Thiesson HC, Skøtt O, Walker BR, Andrew R. McNeilly AD, et al. J Hepatol. 2010 May;52(5):705-11. doi: 10.1016/j.jhep.2009.10.037. Epub 2010 Mar 4. J Hepatol. 2010. PMID: 20347173 Free PMC article.
Glucocorticoid receptor gene expression in adipose tissue and associated metabolic risk in black and white South African women.
Goedecke JH, Chorell E, Livingstone DE, Stimson RH, Hayes P, Adams K, Dave JA, Victor H, Levitt NS, Kahn SE, Seckl JR, Walker BR, Olsson T. Goedecke JH, et al. Int J Obes (Lond). 2015 Feb;39(2):303-11. doi: 10.1038/ijo.2014.94. Epub 2014 May 20. Int J Obes (Lond). 2015. PMID: 24854429
Quantification of 11β-hydroxysteroid dehydrogenase 1 kinetics and pharmacodynamic effects of inhibitors in brain using mass spectrometry imaging and stable-isotope tracers in mice.
Cobice DF, Livingstone DEW, McBride A, MacKay CL, Walker BR, Webster SP, Andrew R. Cobice DF, et al. Biochem Pharmacol. 2018 Feb;148:88-99. doi: 10.1016/j.bcp.2017.12.013. Epub 2017 Dec 15. Biochem Pharmacol. 2018. PMID: 29248595 Free PMC article.
Role of Hepatic Glucocorticoid Receptor in Metabolism in Models of 5αR1 Deficiency in Male Mice.
Mak TCS, Livingstone DEW, Nixon M, Walker BR, Andrew R. Mak TCS, et al. Among authors: livingstone dew. Endocrinology. 2019 Sep 1;160(9):2061-2073. doi: 10.1210/en.2019-00236. Endocrinology. 2019. PMID: 31199473 Free PMC article.
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