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EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis.
Mygland A, Ljøstad U, Fingerle V, Rupprecht T, Schmutzhard E, Steiner I; European Federation of Neurological Societies. Mygland A, et al. Eur J Neurol. 2010 Jan;17(1):8-16, e1-4. doi: 10.1111/j.1468-1331.2009.02862.x. Epub 2009 Nov 23. Eur J Neurol. 2010. PMID: 19930447
BACKGROUND: Lyme neuroborreliosis (LNB) is a nervous system infection caused by Borrelia burgdorferi sensu lato (Bb). ...Children should be treated as adults, except that doxycycline is contraindicated under 8 years of age (nine in some countries). If symptoms persi …
BACKGROUND: Lyme neuroborreliosis (LNB) is a nervous system infection caused by Borrelia burgdorferi sensu lato (Bb). ...Children sho …
Management of neuroborreliosis in European adult patients.
Ljøstad U, Henriksen TH. Ljøstad U, et al. Acta Neurol Scand Suppl. 2008;188:22-8. doi: 10.1111/j.1600-0404.2008.01027.x. Acta Neurol Scand Suppl. 2008. PMID: 18439217 Review.
Two to three weeks courses of IV penicillin or ceftriaxone are highly effective in neuroborreliosis. Oral doxycyclin is probably equally effective. Remaining symptoms five years after treatment for neuroborreliosis are reported in 25-50% of patients. ...The p …
Two to three weeks courses of IV penicillin or ceftriaxone are highly effective in neuroborreliosis. Oral doxycyclin is probab …
Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blinded, randomised and placebo-controlled trial.
Solheim AM, Lorentzen ÅR, Dahlberg AO, Flemmen HØ, Brune S, Forselv KJN, Pripp AH, Bø MH, Eikeland R, Reiso H, Mygland Å, Ljøstad U. Solheim AM, et al. J Neurol Neurosurg Psychiatry. 2022 Jul 27;93(11):1222-8. doi: 10.1136/jnnp-2022-329724. Online ahead of print. J Neurol Neurosurg Psychiatry. 2022. PMID: 35896378 Free PMC article.
BACKGROUND: There is limited evidence regarding optimal duration of antibiotic treatment in neuroborreliosis. We aimed to compare efficacy and safety of oral doxycycline for 2 and 6 weeks in European Lyme neuroborreliosis (LNB). ...Patients with LNB were recr …
BACKGROUND: There is limited evidence regarding optimal duration of antibiotic treatment in neuroborreliosis. We aimed to compare eff …
Six versus two weeks treatment with doxycycline in Lyme neuroborreliosis: the protocol of a multicentre, non-inferiority, double-blinded and randomised controlled trial.
Solheim AM, Ljøstad U, Mygland Å. Solheim AM, et al. BMJ Open. 2019 Jun 14;9(6):e027083. doi: 10.1136/bmjopen-2018-027083. BMJ Open. 2019. PMID: 31201188 Free PMC article.
INTRODUCTION: Current treatment guidelines for European Lyme neuroborreliosis (LNB) recommend cephalosporins, penicillin or doxycycline for 14-28 days but evidence for optimal treatment length is poor. ...The main purpose of our trial is to address the hypothesis of …
INTRODUCTION: Current treatment guidelines for European Lyme neuroborreliosis (LNB) recommend cephalosporins, penicillin or doxycy …
[Lyme borreliosis in adults].
Ljøstad U, Mygland A. Ljøstad U, et al. Tidsskr Nor Laegeforen. 2008 May 15;128(10):1175-8. Tidsskr Nor Laegeforen. 2008. PMID: 18480867 Free article. Norwegian.
Serum neurofilament light chain associates with symptom burden in Lyme neuroborreliosis patients: a longitudinal cohort study from Norway.
Skarstein I, Ulvestad E, Solheim AM, Vedeler C, Ljøstad U, Mygland Å, Eikeland R, Reiso H, Lorentzen ÅR, Bos SD. Skarstein I, et al. J Neurol. 2024 May;271(5):2768-2775. doi: 10.1007/s00415-024-12237-z. Epub 2024 Feb 26. J Neurol. 2024. PMID: 38407594 Free PMC article. Clinical Trial.
In this study, we wanted to investigate sNfL as a prognostic marker in a large, well-defined population of 90 patients with Lyme neuroborreliosis (LNB). In addition, we sought to explore associations between symptoms and sNfL levels during the acute phase of LNB. MATERIALS …
In this study, we wanted to investigate sNfL as a prognostic marker in a large, well-defined population of 90 patients with Lyme neurobor …
Remaining complaints 1 year after treatment for acute Lyme neuroborreliosis; frequency, pattern and risk factors.
Ljøstad U, Mygland A. Ljøstad U, et al. Eur J Neurol. 2010 Jan;17(1):118-23. doi: 10.1111/j.1468-1331.2009.02756.x. Epub 2009 Jul 23. Eur J Neurol. 2010. PMID: 19645771
BACKGROUND AND PURPOSE: To chart remaining complaints 1 year after treatment for neuroborreliosis, and to identify risk factors for a non-favorable outcome. METHODS: We followed patients treated for neuroborreliosis prospectively, and assessed outcome by a composite …
BACKGROUND AND PURPOSE: To chart remaining complaints 1 year after treatment for neuroborreliosis, and to identify risk factors for a …
Risk factors for a non-favorable outcome after treated European neuroborreliosis.
Eikeland R, Mygland Å, Herlofson K, Ljøstad U. Eikeland R, et al. Acta Neurol Scand. 2013 Mar;127(3):154-60. doi: 10.1111/j.1600-0404.2012.01690.x. Epub 2012 Jun 12. Acta Neurol Scand. 2013. PMID: 22690926
AIM: To identify possible risk factors for reduced health-related quality of life (HRQoL) and fatigue after treated Lyme neuroborreliosis (LNB). METHODS: We included 50 patients with LNB and analyzed associations between their demographic, clinical, and laboratory characte …
AIM: To identify possible risk factors for reduced health-related quality of life (HRQoL) and fatigue after treated Lyme neuroborreliosis …
Oral doxycycline versus intravenous ceftriaxone for European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blind, randomised trial.
Ljøstad U, Skogvoll E, Eikeland R, Midgard R, Skarpaas T, Berg A, Mygland A. Ljøstad U, et al. Lancet Neurol. 2008 Aug;7(8):690-5. doi: 10.1016/S1474-4422(08)70119-4. Epub 2008 Jun 21. Lancet Neurol. 2008. PMID: 18567539 Clinical Trial.
BACKGROUND: Use of intravenous penicillin and ceftriaxone to treat Lyme neuroborreliosis is well documented, although oral doxycycline could be a cost-effective alternative. ...Three patients discontinued ceftriaxone treatment owing to adverse events. INTERPRETATION …
BACKGROUND: Use of intravenous penicillin and ceftriaxone to treat Lyme neuroborreliosis is well documented, although oral doxycyc …