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Design of novel antibiotics that bind to the ribosomal acyltransfer site.
Haddad J, Kotra LP, Llano-Sotelo B, Kim C, Azucena EF Jr, Liu M, Vakulenko SB, Chow CS, Mobashery S. Haddad J, et al. Among authors: llano sotelo b. J Am Chem Soc. 2002 Apr 3;124(13):3229-37. doi: 10.1021/ja011695m. J Am Chem Soc. 2002. PMID: 11916405
Selection of small peptides, inhibitors of translation.
Llano-Sotelo B, Klepacki D, Mankin AS. Llano-Sotelo B, et al. J Mol Biol. 2009 Sep 4;391(5):813-9. doi: 10.1016/j.jmb.2009.06.069. Epub 2009 Jul 2. J Mol Biol. 2009. PMID: 19576904 Free PMC article.
Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis.
Llano-Sotelo B, Dunkle J, Klepacki D, Zhang W, Fernandes P, Cate JH, Mankin AS. Llano-Sotelo B, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):4961-70. doi: 10.1128/AAC.00860-10. Epub 2010 Sep 20. Antimicrob Agents Chemother. 2010. PMID: 20855725 Free PMC article.
Fluorescently labeled ribosomes as a tool for analyzing antibiotic binding.
Llano-Sotelo B, Hickerson RP, Lancaster L, Noller HF, Mankin AS. Llano-Sotelo B, et al. RNA. 2009 Aug;15(8):1597-604. doi: 10.1261/rna.1681609. Epub 2009 Jun 24. RNA. 2009. PMID: 19553343 Free PMC article.