Lo DC - Search Results

1

MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling.

Venkatesh D, O'Brien NA, Zandkarimi F, Tong DR, Stokes ME, Dunn DE, Kengmana ES, Aron AT, Klein AM, Csuka JM, Moon SH, Conrad M, Chang CJ, Lo DC, D'Alessandro A, Prives C, Stockwell BR. Venkatesh D, et al. Among authors: lo dc. Genes Dev. 2020 Apr 1;34(7-8):526-543. doi: 10.1101/gad.334219.119. Epub 2020 Feb 20. Genes Dev. 2020. PMID: 32079652 Free PMC article.

2

Small molecule-induced oxidation of protein disulfide isomerase is neuroprotective.

Kaplan A, Gaschler MM, Dunn DE, Colligan R, Brown LM, Palmer AG 3rd, Lo DC, Stockwell BR. Kaplan A, et al. Among authors: lo dc. Proc Natl Acad Sci U S A. 2015 Apr 28;112(17):E2245-52. doi: 10.1073/pnas.1500439112. Epub 2015 Apr 6. Proc Natl Acad Sci U S A. 2015. PMID: 25848045 Free PMC article.

3

Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells.

Shimada K, Reznik E, Stokes ME, Krishnamoorthy L, Bos PH, Song Y, Quartararo CE, Pagano NC, Carpizo DR, deCarvalho AC, Lo DC, Stockwell BR. Shimada K, et al. Among authors: lo dc. Cell Chem Biol. 2018 May 17;25(5):585-594.e7. doi: 10.1016/j.chembiol.2018.02.010. Epub 2018 Mar 22. Cell Chem Biol. 2018. PMID: 29576531 Free PMC article.

4

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models.

Skouta R, Dixon SJ, Wang J, Dunn DE, Orman M, Shimada K, Rosenberg PA, Lo DC, Weinberg JM, Linkermann A, Stockwell BR. Skouta R, et al. Among authors: lo dc. J Am Chem Soc. 2014 Mar 26;136(12):4551-6. doi: 10.1021/ja411006a. Epub 2014 Mar 14. J Am Chem Soc. 2014. PMID: 24592866 Free PMC article.

5

Tumoricidal stem cell therapy enables killing in novel hybrid models of heterogeneous glioblastoma.

Satterlee AB, Dunn DE, Lo DC, Khagi S, Hingtgen S. Satterlee AB, et al. Among authors: lo dc. Neuro Oncol. 2019 Dec 17;21(12):1552-1564. doi: 10.1093/neuonc/noz138. Neuro Oncol. 2019. PMID: 31420675 Free PMC article.

6

High throughput screening for neurodegeneration and complex disease phenotypes.

Varma H, Lo DC, Stockwell BR. Varma H, et al. Among authors: lo dc. Comb Chem High Throughput Screen. 2008 Mar;11(3):238-48. doi: 10.2174/138620708783877753. Comb Chem High Throughput Screen. 2008. PMID: 18336216 Free PMC article. Review.

7

Inhibitors of protein disulfide isomerase suppress apoptosis induced by misfolded proteins.

Hoffstrom BG, Kaplan A, Letso R, Schmid RS, Turmel GJ, Lo DC, Stockwell BR. Hoffstrom BG, et al. Among authors: lo dc. Nat Chem Biol. 2010 Dec;6(12):900-6. doi: 10.1038/nchembio.467. Epub 2010 Oct 31. Nat Chem Biol. 2010. PMID: 21079601 Free PMC article.

8

In vitro and in vivo neuroprotective activity of the cardiac glycoside oleandrin from Nerium oleander in brain slice-based stroke models.

Dunn DE, He DN, Yang P, Johansen M, Newman RA, Lo DC. Dunn DE, et al. Among authors: lo dc. J Neurochem. 2011 Nov;119(4):805-14. doi: 10.1111/j.1471-4159.2011.07439.x. Epub 2011 Sep 26. J Neurochem. 2011. PMID: 21950737 Free article.

9

Selective inhibitors of death in mutant huntingtin cells.

Varma H, Voisine C, DeMarco CT, Cattaneo E, Lo DC, Hart AC, Stockwell BR. Varma H, et al. Among authors: lo dc. Nat Chem Biol. 2007 Feb;3(2):99-100. doi: 10.1038/nchembio852. Epub 2006 Dec 31. Nat Chem Biol. 2007. PMID: 17195849

10

IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance.

Rinkenbaugh AL, Cogswell PC, Calamini B, Dunn DE, Persson AI, Weiss WA, Lo DC, Baldwin AS. Rinkenbaugh AL, et al. Among authors: lo dc. Oncotarget. 2016 Oct 25;7(43):69173-69187. doi: 10.18632/oncotarget.12507. Oncotarget. 2016. PMID: 27732951 Free PMC article.

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