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Probiotics for Prevention and Treatment of Diarrhea.
Guarino A, Guandalini S, Lo Vecchio A. Guarino A, et al. J Clin Gastroenterol. 2015 Nov-Dec;49 Suppl 1:S37-45. doi: 10.1097/MCG.0000000000000349. J Clin Gastroenterol. 2015. PMID: 26447963 Review.
Guidelines did not support a routine use of probiotics and asked for further data for such sensitive implications. In conclusion, there is strong and solid proof of efficacy of probiotics as active treatment of gastroenteritis in addition to rehydration. ...
Guidelines did not support a routine use of probiotics and asked for further data for such sensitive implications. In conclusion, the …
Probiotics as prevention and treatment for diarrhea.
Guarino A, Lo Vecchio A, Canani RB. Guarino A, et al. Curr Opin Gastroenterol. 2009 Jan;25(1):18-23. doi: 10.1097/MOG.0b013e32831b4455. Curr Opin Gastroenterol. 2009. PMID: 19114770 Review.
Selected Lactobacillus strains had a modest, although significant effect in primary prevention. Saccharomyces boulardii was effective in antibiotic-associated and in Clostridium difficile diarrhea. ...However, evidence of efficacy is limited to a few strains....
Selected Lactobacillus strains had a modest, although significant effect in primary prevention. Saccharomyces boulardii was effective …
Clinical role of diosmectite in the management of diarrhea.
Guarino A, Lo Vecchio A, Pirozzi MR. Guarino A, et al. Expert Opin Drug Metab Toxicol. 2009 Apr;5(4):433-40. doi: 10.1517/17425250902865594. Expert Opin Drug Metab Toxicol. 2009. PMID: 19379128 Review.
However, it definitely may play a role in infectious colitis, where treatment options are less convincing. Some available evidences demonstrate a role of DS in functional diarrhea....
However, it definitely may play a role in infectious colitis, where treatment options are less convincing. Some available evidences d …
The applicability and efficacy of guidelines for the management of acute gastroenteritis in outpatient children: a field-randomized trial on primary care pediatricians.
Albano F, Lo Vecchio A, Guarino A. Albano F, et al. J Pediatr. 2010 Feb;156(2):226-30. doi: 10.1016/j.jpeds.2009.07.065. Epub 2009 Oct 15. J Pediatr. 2010. PMID: 19836027 Clinical Trial.
STUDY DESIGN: This was a national, open, randomized, controlled intervention trial. The intervention consisted of a 2-hour course based on the guidelines for management of AGE. ...RESULTS: The baseline features of the children were similar in groups A (n = 61 …
STUDY DESIGN: This was a national, open, randomized, controlled intervention trial. The intervention consisted of a 2-hour cou …
Evaluation of the quality of guidelines for acute gastroenteritis in children with the AGREE instrument.
Lo Vecchio A, Giannattasio A, Duggan C, De Masi S, Ortisi MT, Parola L, Guarino A. Lo Vecchio A, et al. J Pediatr Gastroenterol Nutr. 2011 Feb;52(2):183-9. doi: 10.1097/MPG.0b013e3181e233ac. J Pediatr Gastroenterol Nutr. 2011. PMID: 20808248 Free PMC article.
AIM: The aim of the study was to assess the quality of clinical practice guidelines (CPGs) using the Appraisal of Guidelines for Research and Evaluation (AGREE) instrument, a validated international tool. ...AGREE consists of 6 domains for a total of 23 items. RESUL …
AIM: The aim of the study was to assess the quality of clinical practice guidelines (CPGs) using the Appraisal of Guidelines for Research an …
Flu and pneumococcal immunisations in HIV-infected children: methodological quality of current recommendations.
Giannattasio A, Lo Vecchio A, Albano F, Giacomet V, Barbarino A, Guarino A. Giannattasio A, et al. BMJ Qual Saf. 2011 May;20(5):432-9. doi: 10.1136/bmjqs.2010.047316. Epub 2011 Feb 2. BMJ Qual Saf. 2011. PMID: 21292690 Review.
The management of acute diarrhea in children in developed and developing areas: from evidence base to clinical practice.
Guarino A, Dupont C, Gorelov AV, Gottrand F, Lee JK, Lin Z, Lo Vecchio A, Nguyen TD, Salazar-Lindo E. Guarino A, et al. Expert Opin Pharmacother. 2012 Jan;13(1):17-26. doi: 10.1517/14656566.2011.634800. Epub 2011 Nov 22. Expert Opin Pharmacother. 2012. PMID: 22106840 Review.
INTRODUCTION: Acute diarrhea remains a major problem in children and is associated with substantial morbidity, mortality and costs. ...Transfer to clinical practice should result from the implementation of guidelines tailored at a local level, with an eye on costs.. …
INTRODUCTION: Acute diarrhea remains a major problem in children and is associated with substantial morbidity, mortality and costs. . …
Clostridium difficile infection: an update on epidemiology, risk factors, and therapeutic options.
Lo Vecchio A, Zacur GM. Lo Vecchio A, et al. Curr Opin Gastroenterol. 2012 Jan;28(1):1-9. doi: 10.1097/MOG.0b013e32834bc9a9. Curr Opin Gastroenterol. 2012. PMID: 22134217 Review.
New antibiotics with selected action on C. difficile and limited effect on microflora (fidaxomicin) and donor fecal transplantation seem to have a relevant efficacy in treating CDI and reducing its recurrence. The use of selected monoclonal antibodies directed against C. d …
New antibiotics with selected action on C. difficile and limited effect on microflora (fidaxomicin) and donor fecal transplantation seem to …
Hospital management of children with acute gastroenteritis.
Bruzzese E, Lo Vecchio A, Guarino A. Bruzzese E, et al. Curr Opin Gastroenterol. 2013 Jan;29(1):23-30. doi: 10.1097/MOG.0b013e32835a352f. Curr Opin Gastroenterol. 2013. PMID: 23196854 Review.
The need of intravenous (i.v.) rehydration is the main cause of hospital admission yet a standardized rehydration scheme is not available. ...SUMMARY: Inappropriate medical interventions are still common in the hospital setting and have a high impact on costs. A
The need of intravenous (i.v.) rehydration is the main cause of hospital admission yet a standardized rehydration scheme is not avail …
Chronic diarrhoea in children.
Guarino A, Lo Vecchio A, Berni Canani R. Guarino A, et al. Best Pract Res Clin Gastroenterol. 2012 Oct;26(5):649-61. doi: 10.1016/j.bpg.2012.11.004. Best Pract Res Clin Gastroenterol. 2012. PMID: 23384809
Coeliac disease is a major cause of diarrhoea throughout childhood. In neonates, congenital diarrhoea is a rare but severe syndrome that includes several highly complex diseases. ...A stepwise approach may reduce the need of endoscopy, also in the light of it …
Coeliac disease is a major cause of diarrhoea throughout childhood. In neonates, congenital diarrhoea is a rare but severe syn …
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