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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1949 3
1950 9
1951 13
1952 18
1953 15
1954 15
1955 16
1956 14
1957 6
1958 7
1959 11
1960 10
1961 4
1962 13
1963 36
1964 68
1965 81
1966 72
1967 59
1968 77
1969 93
1970 76
1971 82
1972 98
1973 61
1974 116
1975 130
1976 112
1977 114
1978 104
1979 118
1980 130
1981 113
1982 129
1983 136
1984 145
1985 169
1986 165
1987 167
1988 193
1989 234
1990 271
1991 264
1992 278
1993 276
1994 267
1995 354
1996 471
1997 476
1998 531
1999 498
2000 491
2001 459
2002 464
2003 438
2004 492
2005 470
2006 534
2007 557
2008 565
2009 605
2010 601
2011 566
2012 636
2013 596
2014 610
2015 541
2016 591
2017 545
2018 581
2019 577
2020 630
2021 630
2022 481
2023 463
2024 560
2025 208

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19,332 results

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Page 1
Perioperative Use of Intravenous Lidocaine.
Beaussier M, Delbos A, Maurice-Szamburski A, Ecoffey C, Mercadal L. Beaussier M, et al. Drugs. 2018 Aug;78(12):1229-1246. doi: 10.1007/s40265-018-0955-x. Drugs. 2018. PMID: 30117019 Review.
Lidocaine is an amide local anaesthetic initially used intravenously as an antiarrhythmic agent. ...IVL is rapidly distributed in the body and metabolized by the liver. With the commonly recommended doses, lidocaine's therapeutic index remains very hig …
Lidocaine is an amide local anaesthetic initially used intravenously as an antiarrhythmic agent. ...IVL is rapidly distributed …
The role of lidocaine in cancer progression and patient survival.
Chida K, Kanazawa H, Kinoshita H, Roy AM, Hakamada K, Takabe K. Chida K, et al. Pharmacol Ther. 2024 Jul;259:108654. doi: 10.1016/j.pharmthera.2024.108654. Epub 2024 May 1. Pharmacol Ther. 2024. PMID: 38701900 Review.
Since its development in 1943, lidocaine has been one of the most commonly used local anesthesia agents for surgical procedures. ...Taken together, there remains significant ambiguity surrounding lidocaine's functions and roles in cancer biology, parti …
Since its development in 1943, lidocaine has been one of the most commonly used local anesthesia agents for surgical procedure …
Lidocaine and seizures.
DeToledo JC. DeToledo JC. Ther Drug Monit. 2000 Jun;22(3):320-2. doi: 10.1097/00007691-200006000-00014. Ther Drug Monit. 2000. PMID: 10850400 Review.
Seizures induced by lidocaine in experimental conditions invariably start in the amygdala. Despite the clear focal onset in these experimental models, the seizures emerging in patients given intravenous (i.v.) lidocaine are almost invariably generalized and w …
Seizures induced by lidocaine in experimental conditions invariably start in the amygdala. Despite the clear focal onset in th …
Eutectic lidocaine/prilocaine cream. A review of the topical anaesthetic/analgesic efficacy of a eutectic mixture of local anaesthetics (EMLA).
Buckley MM, Benfield P. Buckley MM, et al. Drugs. 1993 Jul;46(1):126-51. doi: 10.2165/00003495-199346010-00008. Drugs. 1993. PMID: 7691503 Review.
Eutectic lidocaine/prilocaine cream 5% is a eutectic mixture of the local anaesthetics lidocaine (lignocaine) 25 mg/g and prilocaine 25 mg/g that provides dermal anaesthesia/analgesia following topical application. ...Particular benefit has also been s …
Eutectic lidocaine/prilocaine cream 5% is a eutectic mixture of the local anaesthetics lidocaine (lignocaine) 25 …
Local anesthetic systemic toxicity in the pediatric patient.
McMahon K, Paster J, Baker KA. McMahon K, et al. Am J Emerg Med. 2022 Apr;54:325.e3-325.e6. doi: 10.1016/j.ajem.2021.10.021. Epub 2021 Oct 25. Am J Emerg Med. 2022. PMID: 34742600 Review.
Lidocaine and prilocaine are local anesthetics, a class of medications which are frequently used in clinical medicine to minimize pain in a variety of procedures. ...Methemoglobinemia may also be associated with local anesthetic toxicity. Our case involves a …
Lidocaine and prilocaine are local anesthetics, a class of medications which are frequently used in clinical medicine to minim …
Targeted local anesthesia: a novel slow-release Fe(3)O(4)-lidocaine-PLGA microsphere endowed with a magnetic targeting function.
Zheng LX, Yu Q, Li Q, Zheng CD. Zheng LX, et al. J Anesth. 2024 Apr;38(2):232-243. doi: 10.1007/s00540-023-03305-1. Epub 2024 Feb 4. J Anesth. 2024. PMID: 38310577
Therefore, we added Fe(3)O(4) to the lidocaine microspheres and used an applied magnetic field to attract Fe(3)O(4) to fix the microspheres around the target nerves, reducing the diffusion of magnetic lidocaine microspheres to the surrounding tissues and prolonging …
Therefore, we added Fe(3)O(4) to the lidocaine microspheres and used an applied magnetic field to attract Fe(3)O(4) to fix the micros …
Population Pharmacokinetics of Intravenous Lidocaine in Adults: A Systematic Review.
Foong KW, Chaw SH, Lo YL, Loh PS. Foong KW, et al. Clin Pharmacokinet. 2024 May;63(5):623-643. doi: 10.1007/s40262-024-01373-4. Epub 2024 May 4. Clin Pharmacokinet. 2024. PMID: 38703307
OBJECTIVES: This systematic review compiles the existing knowledge on lidocaine's PK properties and published popPK models, with a focus on significant covariates. ...This comprehensive review advances our understanding of lidocaine's pharmacokinetics …
OBJECTIVES: This systematic review compiles the existing knowledge on lidocaine's PK properties and published popPK models, wi …
Buffering lidocaine heightens aversion to cornual nerve injections in dairy calves.
Adcock SJJ, Tucker CB. Adcock SJJ, et al. J Dairy Sci. 2022 May;105(5):4490-4497. doi: 10.3168/jds.2021-21012. Epub 2022 Mar 26. J Dairy Sci. 2022. PMID: 35346475 Free article.
Best practice is to numb the horn buds before disbudding dairy calves, which can be achieved by injecting lidocaine, a local anesthetic, around the cornual nerve. In humans, the acute pain that occurs upon injection of lidocaine can be reduced by neutralizing …
Best practice is to numb the horn buds before disbudding dairy calves, which can be achieved by injecting lidocaine, a local a …
Lidocaine for Cancer Pain in Adults: A Systematic Review and Meta-Analysis.
Lee JT, Sanderson CR, Xuan W, Agar M. Lee JT, et al. J Palliat Med. 2019 Mar;22(3):326-334. doi: 10.1089/jpm.2018.0257. Epub 2019 Jan 7. J Palliat Med. 2019. PMID: 30614748
BACKGROUND: Internationally, use of lidocaine infusions to treat cancer pain varies by center. Existing systematic reviews do not adequately inform use of lidocaine in cancer pain. ...RESULTS: One positive (n = 50) and three negative (n = 10 each) crossover trials e …
BACKGROUND: Internationally, use of lidocaine infusions to treat cancer pain varies by center. Existing systematic reviews do not ade …
Intratympanic Lidocaine as a Potent Remedy for Tinnitus in Sudden Sensorineural Hearing Loss: A Double-Blind, Randomized Clinical Trial.
Zhang D, Li D, Chen T, Feng X, Zhang J. Zhang D, et al. Otol Neurotol. 2024 Sep 1;45(8):849-854. doi: 10.1097/MAO.0000000000004283. Epub 2024 Jul 25. Otol Neurotol. 2024. PMID: 39052899 Clinical Trial.
OBJECTIVE: This study evaluates intratympanic lidocaine's efficacy and safety for tinnitus relief in sudden sensorineural hearing loss (SSNHL) patients. ...CONCLUSION: Intratympanic lidocaine provides a safe, efficacious treatment option for SSNHL tinnitus. F …
OBJECTIVE: This study evaluates intratympanic lidocaine's efficacy and safety for tinnitus relief in sudden sensorineural hear …
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