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Cancer's insatiable appetite.
Locasale JW, Cantley LC, Vander Heiden MG. Locasale JW, et al. Nat Biotechnol. 2009 Oct;27(10):916-7. doi: 10.1038/nbt1009-916. Nat Biotechnol. 2009. PMID: 19816448 Free PMC article.
Altered metabolism in cancer.
Locasale JW, Cantley LC. Locasale JW, et al. BMC Biol. 2010 Jun 25;8:88. doi: 10.1186/1741-7007-8-88. BMC Biol. 2010. PMID: 20598111 Free PMC article.
Evidence for an alternative glycolytic pathway in rapidly proliferating cells.
Vander Heiden MG, Locasale JW, Swanson KD, Sharfi H, Heffron GJ, Amador-Noguez D, Christofk HR, Wagner G, Rabinowitz JD, Asara JM, Cantley LC. Vander Heiden MG, et al. Among authors: locasale jw. Science. 2010 Sep 17;329(5998):1492-9. doi: 10.1126/science.1188015. Science. 2010. PMID: 20847263 Free PMC article.
Rewiring of glycolysis in cancer cell metabolism.
Locasale JW, Vander Heiden MG, Cantley LC. Locasale JW, et al. Cell Cycle. 2010 Nov 1;9(21):4253. doi: 10.4161/cc.9.21.13925. Epub 2010 Nov 7. Cell Cycle. 2010. PMID: 21045562 No abstract available.
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis.
Locasale JW, Grassian AR, Melman T, Lyssiotis CA, Mattaini KR, Bass AJ, Heffron G, Metallo CM, Muranen T, Sharfi H, Sasaki AT, Anastasiou D, Mullarky E, Vokes NI, Sasaki M, Beroukhim R, Stephanopoulos G, Ligon AH, Meyerson M, Richardson AL, Chin L, Wagner G, Asara JM, Brugge JS, Cantley LC, Vander Heiden MG. Locasale JW, et al. Nat Genet. 2011 Jul 31;43(9):869-74. doi: 10.1038/ng.890. Nat Genet. 2011. PMID: 21804546 Free PMC article.
Metabolic regulation of protein N-alpha-acetylation by Bcl-xL promotes cell survival.
Yi CH, Pan H, Seebacher J, Jang IH, Hyberts SG, Heffron GJ, Vander Heiden MG, Yang R, Li F, Locasale JW, Sharfi H, Zhai B, Rodriguez-Mias R, Luithardt H, Cantley LC, Daley GQ, Asara JM, Gygi SP, Wagner G, Liu CF, Yuan J. Yi CH, et al. Among authors: locasale jw. Cell. 2011 Aug 19;146(4):607-20. doi: 10.1016/j.cell.2011.06.050. Cell. 2011. PMID: 21854985 Free PMC article.
PHGDH amplification and altered glucose metabolism in human melanoma.
Mullarky E, Mattaini KR, Vander Heiden MG, Cantley LC, Locasale JW. Mullarky E, et al. Among authors: locasale jw. Pigment Cell Melanoma Res. 2011 Dec;24(6):1112-5. doi: 10.1111/j.1755-148X.2011.00919.x. Epub 2011 Oct 28. Pigment Cell Melanoma Res. 2011. PMID: 21981974 Review.
216 results