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Expression of the E6 and E7 genes of human papillomavirus (HPV16) extends the life span of human myoblasts.
Lochmüller H, Johns T, Shoubridge EA. Lochmüller H, et al. Exp Cell Res. 1999 Apr 10;248(1):186-93. doi: 10.1006/excr.1999.4407. Exp Cell Res. 1999. PMID: 10094825
Adenovirus-mediated wild-type p53 gene transfer and overexpression induces apoptosis of human glioma cells independent of endogenous p53 status.
Li H, Lochmüller H, Yong VW, Karpati G, Nalbantoglu J. Li H, et al. Among authors: lochmuller h. J Neuropathol Exp Neurol. 1997 Aug;56(8):872-8. doi: 10.1097/00005072-199708000-00005. J Neuropathol Exp Neurol. 1997. PMID: 9258257
Intracerebral adenovirus-mediated p53 tumor suppressor gene therapy for experimental human glioma.
Li H, Alonso-Vanegas M, Colicos MA, Jung SS, Lochmuller H, Sadikot AF, Snipes GJ, Seth P, Karpati G, Nalbantoglu J. Li H, et al. Among authors: lochmuller h. Clin Cancer Res. 1999 Mar;5(3):637-42. Clin Cancer Res. 1999. PMID: 10100717
Muscle-specific overexpression of the adenovirus primary receptor CAR overcomes low efficiency of gene transfer to mature skeletal muscle.
Nalbantoglu J, Larochelle N, Wolf E, Karpati G, Lochmuller H, Holland PC. Nalbantoglu J, et al. Among authors: lochmuller h. J Virol. 2001 May;75(9):4276-82. doi: 10.1128/JVI.75.9.4276-4282.2001. J Virol. 2001. PMID: 11287577 Free PMC article.
Adenovirus-mediated gene transfer of the tumor suppressor, p53, induces apoptosis in postmitotic neurons.
Slack RS, Belliveau DJ, Rosenberg M, Atwal J, Lochmüller H, Aloyz R, Haghighi A, Lach B, Seth P, Cooper E, Miller FD. Slack RS, et al. Among authors: lochmuller h. J Cell Biol. 1996 Nov;135(4):1085-96. doi: 10.1083/jcb.135.4.1085. J Cell Biol. 1996. PMID: 8922388 Free PMC article.
Transient immunosuppression by FK506 permits a sustained high-level dystrophin expression after adenovirus-mediated dystrophin minigene transfer to skeletal muscles of adult dystrophic (mdx) mice.
Lochmüller H, Petrof BJ, Pari G, Larochelle N, Dodelet V, Wang Q, Allen C, Prescott S, Massie B, Nalbantoglu J, Karpati G. Lochmüller H, et al. Gene Ther. 1996 Aug;3(8):706-16. Gene Ther. 1996. PMID: 8854096
Toxicity of replication-defective adenoviral recombinants in dissociated cultures of nervous tissue.
Durham HD, Lochmüller H, Jani A, Acsadi G, Massie B, Karpati G. Durham HD, et al. Among authors: lochmuller h. Exp Neurol. 1996 Jul;140(1):14-20. doi: 10.1006/exnr.1996.0110. Exp Neurol. 1996. PMID: 8682175
Differential short-term transduction efficiency of adult versus newborn mouse tissues by adenoviral recombinants.
Huard J, Lochmüller H, Acsadi G, Jani A, Holland P, Guérin C, Massie B, Karpati G. Huard J, et al. Among authors: lochmuller h. Exp Mol Pathol. 1995 Apr;62(2):131-43. doi: 10.1006/exmp.1995.1015. Exp Mol Pathol. 1995. PMID: 8549697
Cultured human myoblasts and myotubes show markedly different transducibility by replication-defective adenovirus recombinants.
Acsadi G, Jani A, Huard J, Blaschuk K, Massie B, Holland P, Lochmüller H, Karpati G. Acsadi G, et al. Among authors: lochmuller h. Gene Ther. 1994 Sep;1(5):338-40. Gene Ther. 1994. PMID: 7584100
Immunosuppression by FK506 markedly prolongs expression of adenovirus-delivered transgene in skeletal muscles of adult dystrophic [mdx] mice.
Lochmüller H, Petrof BJ, Allen C, Prescott S, Massie B, Karpati G. Lochmüller H, et al. Biochem Biophys Res Commun. 1995 Aug 15;213(2):569-74. doi: 10.1006/bbrc.1995.2169. Biochem Biophys Res Commun. 1995. PMID: 7544122
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