Lochner M - Search Results

1

Characterization of Novel Fluorescent Bile Salt Derivatives for Studying Human Bile Salt and Organic Anion Transporters.

Leuenberger M, Häusler S, Höhn V, Euler A, Stieger B, Lochner M. Leuenberger M, et al. Among authors: lochner m. J Pharmacol Exp Ther. 2021 Jun;377(3):346-357. doi: 10.1124/jpet.120.000449. Epub 2021 Mar 29. J Pharmacol Exp Ther. 2021. PMID: 33782042 Free article.

2

The binding orientations of structurally-related ligands can differ; A cautionary note.

Ruepp MD, Wei H, Leuenberger M, Lochner M, Thompson AJ. Ruepp MD, et al. Among authors: lochner m. Neuropharmacology. 2017 Jun;119:48-61. doi: 10.1016/j.neuropharm.2017.01.023. Epub 2017 Jan 27. Neuropharmacology. 2017. PMID: 28137449 Free PMC article.

3

Concise Asymmetric Synthesis and Pharmacological Characterization of All Stereoisomers of Glutamate Transporter Inhibitor TFB-TBOA and Synthesis of EAAT Photoaffinity Probes.

Leuenberger M, Ritler A, Simonin A, Hediger MA, Lochner M. Leuenberger M, et al. Among authors: lochner m. ACS Chem Neurosci. 2016 May 18;7(5):534-9. doi: 10.1021/acschemneuro.5b00311. Epub 2016 Mar 3. ACS Chem Neurosci. 2016. PMID: 26918289

4

Design, synthesis and pharmacological characterization of analogs of 2-aminoethyl diphenylborinate (2-APB), a known store-operated calcium channel blocker, for inhibition of TRPV6-mediated calcium transport.

Hofer A, Kovacs G, Zappatini A, Leuenberger M, Hediger MA, Lochner M. Hofer A, et al. Among authors: lochner m. Bioorg Med Chem. 2013 Jun 1;21(11):3202-13. doi: 10.1016/j.bmc.2013.03.037. Epub 2013 Apr 1. Bioorg Med Chem. 2013. PMID: 23602525

5

Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity.

Knight A, Hemmings JL, Winfield I, Leuenberger M, Frattini E, Frenguelli BG, Dowell SJ, Lochner M, Ladds G. Knight A, et al. Among authors: lochner m. J Med Chem. 2016 Feb 11;59(3):947-64. doi: 10.1021/acs.jmedchem.5b01402. Epub 2016 Feb 1. J Med Chem. 2016. PMID: 26756468 Free article.

6

Mapping the Orthosteric Binding Site of the Human 5-HT₃ Receptor Using Photo-cross-linking Antagonists.

Jack T, Leuenberger M, Ruepp MD, Vernekar SKV, Thompson AJ, Braga-Lagache S, Heller M, Lochner M. Jack T, et al. Among authors: lochner m. ACS Chem Neurosci. 2019 Jan 16;10(1):438-450. doi: 10.1021/acschemneuro.8b00327. Epub 2018 Sep 11. ACS Chem Neurosci. 2019. PMID: 30149702

7

The SLC1 high-affinity glutamate and neutral amino acid transporter family.

Kanai Y, Clémençon B, Simonin A, Leuenberger M, Lochner M, Weisstanner M, Hediger MA. Kanai Y, et al. Among authors: lochner m. Mol Aspects Med. 2013 Apr-Jun;34(2-3):108-20. doi: 10.1016/j.mam.2013.01.001. Mol Aspects Med. 2013. PMID: 23506861 Review.

8

Correction to Discovery of Novel Adenosine Receptor Agonists That Exhibit Subtype Selectivity.

Knight A, Hemmings JL, Winfield I, Leuenberger M, Frattini E, Frenguelli BG, Dowell SJ, Lochner M, Ladds G. Knight A, et al. Among authors: lochner m. J Med Chem. 2020 Sep 24;63(18):10531. doi: 10.1021/acs.jmedchem.0c01416. Epub 2020 Sep 1. J Med Chem. 2020. PMID: 32870678 No abstract available.

9

The antimalarial drug proguanil is an antagonist at 5-HT3 receptors.

Lochner M, Thompson AJ. Lochner M, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):674-84. doi: 10.1124/jpet.114.218461. Epub 2014 Oct 2. J Pharmacol Exp Ther. 2014. PMID: 25277140

10

A review of fluorescent ligands for studying 5-HT3 receptors.

Lochner M, Thompson AJ. Lochner M, et al. Neuropharmacology. 2015 Nov;98:31-40. doi: 10.1016/j.neuropharm.2015.04.002. Epub 2015 Apr 16. Neuropharmacology. 2015. PMID: 25892507 Review.

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