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Adeno-associated viruses as liver-directed gene delivery vehicles: focus on lipoprotein metabolism.
Lagor WR, Johnston JC, Lock M, Vandenberghe LH, Rader DJ. Lagor WR, et al. Among authors: lock m. Methods Mol Biol. 2013;1027:273-307. doi: 10.1007/978-1-60327-369-5_13. Methods Mol Biol. 2013. PMID: 23912992
Efficient serotype-dependent release of functional vector into the culture medium during adeno-associated virus manufacturing.
Vandenberghe LH, Xiao R, Lock M, Lin J, Korn M, Wilson JM. Vandenberghe LH, et al. Among authors: lock m. Hum Gene Ther. 2010 Oct;21(10):1251-7. doi: 10.1089/hum.2010.107. Hum Gene Ther. 2010. PMID: 20649475 Free PMC article.
Rapid, simple, and versatile manufacturing of recombinant adeno-associated viral vectors at scale.
Lock M, Alvira M, Vandenberghe LH, Samanta A, Toelen J, Debyser Z, Wilson JM. Lock M, et al. Hum Gene Ther. 2010 Oct;21(10):1259-71. doi: 10.1089/hum.2010.055. Hum Gene Ther. 2010. PMID: 20497038 Free PMC article.
Characterization of a recombinant adeno-associated virus type 2 Reference Standard Material.
Lock M, McGorray S, Auricchio A, Ayuso E, Beecham EJ, Blouin-Tavel V, Bosch F, Bose M, Byrne BJ, Caton T, Chiorini JA, Chtarto A, Clark KR, Conlon T, Darmon C, Doria M, Douar A, Flotte TR, Francis JD, Francois A, Giacca M, Korn MT, Korytov I, Leon X, Leuchs B, Lux G, Melas C, Mizukami H, Moullier P, Müller M, Ozawa K, Philipsberg T, Poulard K, Raupp C, Rivière C, Roosendaal SD, Samulski RJ, Soltys SM, Surosky R, Tenenbaum L, Thomas DL, van Montfort B, Veres G, Wright JF, Xu Y, Zelenaia O, Zentilin L, Snyder RO. Lock M, et al. Hum Gene Ther. 2010 Oct;21(10):1273-85. doi: 10.1089/hum.2009.223. Hum Gene Ther. 2010. PMID: 20486768 Free PMC article.
Production of recombinant adeno-associated type 5 (rAAV5) vectors using recombinant herpes simplex viruses containing rep and cap.
Wustner JT, Arnold S, Lock M, Richardson JC, Himes VB, Kurtzman G, Peluso RW. Wustner JT, et al. Among authors: lock m. Mol Ther. 2002 Oct;6(4):510-8. doi: 10.1006/mthe.2002.0695. Mol Ther. 2002. PMID: 12377193
Deamidation of Amino Acids on the Surface of Adeno-Associated Virus Capsids Leads to Charge Heterogeneity and Altered Vector Function.
Giles AR, Sims JJ, Turner KB, Govindasamy L, Alvira MR, Lock M, Wilson JM. Giles AR, et al. Among authors: lock m. Mol Ther. 2018 Dec 5;26(12):2848-2862. doi: 10.1016/j.ymthe.2018.09.013. Epub 2018 Oct 18. Mol Ther. 2018. PMID: 30343890 Free PMC article.
Corrigendum to "Biology of AAV Serotype Vectors in Liver-Directed Gene Transfer to Nonhuman Primates".
Gao G, Lu Y, Calcedo R, Grant RL, Bell P, Wang L, Figueredo J, Lock M, Wilson JM. Gao G, et al. Among authors: lock m. Mol Ther. 2006 Jul;14(1):150. doi: 10.1016/j.ymthe.2006.04.002. Epub 2006 May 30. Mol Ther. 2006. PMID: 28192691 No abstract available.
Identification of an adeno-associated virus binding epitope for AVB sepharose affinity resin.
Wang Q, Lock M, Prongay AJ, Alvira MR, Petkov B, Wilson JM. Wang Q, et al. Among authors: lock m. Mol Ther Methods Clin Dev. 2015 Nov 4;2:15040. doi: 10.1038/mtm.2015.40. eCollection 2015. Mol Ther Methods Clin Dev. 2015. PMID: 26605372 Free PMC article.
Absolute determination of single-stranded and self-complementary adeno-associated viral vector genome titers by droplet digital PCR.
Lock M, Alvira MR, Chen SJ, Wilson JM. Lock M, et al. Hum Gene Ther Methods. 2014 Apr;25(2):115-25. doi: 10.1089/hgtb.2013.131. Epub 2014 Feb 14. Hum Gene Ther Methods. 2014. PMID: 24328707 Free PMC article.
Biodistribution of AAV8 vectors expressing human low-density lipoprotein receptor in a mouse model of homozygous familial hypercholesterolemia.
Chen SJ, Sanmiguel J, Lock M, McMenamin D, Draper C, Limberis MP, Kassim SH, Somanathan S, Bell P, Johnston JC, Rader DJ, Wilson JM. Chen SJ, et al. Among authors: lock m. Hum Gene Ther Clin Dev. 2013 Dec;24(4):154-60. doi: 10.1089/humc.2013.082. Epub 2013 Nov 9. Hum Gene Ther Clin Dev. 2013. PMID: 24070336 Free PMC article.
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