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407 results
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Preclinical efficacy of azacitidine and venetoclax for infant KMT2A-rearranged acute lymphoblastic leukemia reveals a new therapeutic strategy.
Cheung LC, Aya-Bonilla C, Cruickshank MN, Chiu SK, Kuek V, Anderson D, Chua GA, Singh S, Oommen J, Ferrari E, Hughes AM, Ford J, Kunold E, Hesselman MC, Post F, Faulk KE, Breese EH, Guest EM, Brown PA, Loh ML, Lock RB, Kees UR, Jafari R, Malinge S, Kotecha RS. Cheung LC, et al. Among authors: lock rb. Leukemia. 2022 Nov 15. doi: 10.1038/s41375-022-01746-3. Online ahead of print. Leukemia. 2022. PMID: 36380143
STK25 inhibits PKA signaling by phosphorylating PRKAR1A.
Zhang X, Wang BZ, Kim M, Nash TR, Liu B, Rao J, Lock R, Tamargo M, Soni RK, Belov J, Li E, Vunjak-Novakovic G, Fine B. Zhang X, et al. Among authors: lock r. Cell Rep. 2022 Aug 16;40(7):111203. doi: 10.1016/j.celrep.2022.111203. Cell Rep. 2022. PMID: 35977512 Free PMC article.
The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.
Xiao L, Karsa M, Ronca E, Bongers A, Kosciolek A, El-Ayoubi A, Revalde JL, Seneviratne JA, Cheung BB, Cheung LC, Kotecha RS, Newbold A, Bjelosevic S, Arndt GM, Lock RB, Johnstone RW, Gudkov AV, Gurova KV, Haber M, Norris MD, Henderson MJ, Somers K. Xiao L, et al. Among authors: lock rb. Front Oncol. 2022 May 23;12:863329. doi: 10.3389/fonc.2022.863329. eCollection 2022. Front Oncol. 2022. PMID: 35677155 Free PMC article.
Circulating Tumor DNA in Pediatric Cancer.
Doculara L, Trahair TN, Bayat N, Lock RB. Doculara L, et al. Among authors: lock rb. Front Mol Biosci. 2022 May 12;9:885597. doi: 10.3389/fmolb.2022.885597. eCollection 2022. Front Mol Biosci. 2022. PMID: 35647029 Free PMC article. Review.
In vitro and in vivo drug screens of tumor cells identify novel therapies for high-risk child cancer.
Lau LMS, Mayoh C, Xie J, Barahona P, MacKenzie KL, Wong M, Kamili A, Tsoli M, Failes TW, Kumar A, Mould EVA, Gifford A, Chow SO, Pinese M, Fletcher JI, Arndt GM, Khuong-Quang DA, Wadham C, Batey D, Eden G, Trebilcock P, Joshi S, Alfred S, Gopalakrishnan A, Khan A, Grebert Wade D, Strong PA, Manouvrier E, Morgan LT, Span M, Lim JY, Cadiz R, Ung C, Thomas DM, Tucker KM, Warby M, McCowage GB, Dalla-Pozza L, Byrne JA, Saletta F, Fellowes A, Fox SB, Norris MD, Tyrrell V, Trahair TN, Lock RB, Cowley MJ, Ekert PG, Haber M, Ziegler DS, Marshall GM. Lau LMS, et al. Among authors: lock rb. EMBO Mol Med. 2022 Apr 7;14(4):e14608. doi: 10.15252/emmm.202114608. Epub 2021 Dec 20. EMBO Mol Med. 2022. PMID: 34927798 Free PMC article.
407 results